| Microfluidic formulation of nanoparticles for biomedical applications SJ Shepherd, D Issadore, MJ Mitchell Biomaterials 274, 120826, 2021 | 183 | 2021 |
| Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device SJ Shepherd, CC Warzecha, S Yadavali, R El-Mayta, MG Alameh, ... Nano Letters 21 (13), 5671-5680, 2021 | 140 | 2021 |
| Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver R Zhang, R El-Mayta, TJ Murdoch, CC Warzecha, MM Billingsley, ... Biomaterials Science 9 (4), 1449-1463, 2021 | 107 | 2021 |
| Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment L Xue, N Gong, SJ Shepherd, X Xiong, X Liao, X Han, G Zhao, C Song, ... Journal of the American Chemical Society 144 (22), 9926-9937, 2022 | 56 | 2022 |
| Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis X Han, N Gong, L Xue, MM Billingsley, R El-Mayta, SJ Shepherd, ... Nature Communications 14 (1), 75, 2023 | 41 | 2023 |
| Nanoparticle protein corona: from structure and function to therapeutic targeting G Bashiri, MS Padilla, KL Swingle, SJ Shepherd, MJ Mitchell, K Wang, ... Lab Chip 23, 1531, 2023 | 36 | 2023 |
| Rational design of anti‐inflammatory lipid nanoparticles for mRNA delivery H Zhang, X Han, MG Alameh, SJ Shepherd, MS Padilla, L Xue, ... Journal of Biomedical Materials Research Part A 110 (5), 1101-1108, 2022 | 28 | 2022 |
| A Nanoparticle Platform for Accelerated In Vivo Oral Delivery Screening of Nucleic Acids R El‐Mayta, R Zhang, SJ Shepherd, F Wang, MM Billingsley, V Dudkin, ... Advanced Therapeutics 4 (1), 2000111, 2021 | 21 | 2021 |
| RGD peptide-based lipids for targeted mRNA delivery and gene editing applications J Qin, L Xue, N Gong, H Zhang, SJ Shepherd, RM Haley, KL Swingle, ... RSC Advances 12 (39), 25397-25404, 2022 | 20 | 2022 |
| Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ... Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023 | 16 | 2023 |
| In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy PPG Guimarães, CG Figueroa-Espada, RS Riley, N Gong, L Xue, ... Proceedings of the National Academy of Sciences 120 (25), e2215711120, 2023 | 15 | 2023 |
| High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models L Xue, AG Hamilton, G Zhao, Z Xiao, R El-Mayta, X Han, N Gong, X Xiong, ... Nature Communications 15 (1), 1884, 2024 | 1 | 2024 |
| Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models LC Guimaraes, PAC Costa, SRA Scalzo Júnior, HAS Ferreira, ACS Braga, ... Nature Communications 15 (1), 590, 2024 | 1 | 2024 |
| Microfluidic platforms for large scale nanoparticle formulations MJ Mitchell, DA Issadore, SP Yadavali, SJ Shepherd US Patent App. 18/259,439, 2024 | | 2024 |
| Microfluidics for throughput scalable formulation of mRNA lipid nanoparticle technology S Shepherd University of Pennsylvania, 2023 | | 2023 |
| Towards the Clinical Translation of a Silver Sulfide Nanoparticle Contrast Agent: Large Scale Production with a Highly Parallelized Microfluidic Chip KJ Mossburg, SJ Shepherd, D Barragan, NH O, EK Berkow, ... bioRxiv, 2023.12. 02.569706, 2023 | | 2023 |
| Redefining the characterization paradigm of RNA lipid nanoparticles SJ Shepherd, MS Padilla, K Gupta, D Issadore, MJ Mitchell Acta Crystallographica Section A: Foundations of Crystallography 79, a118-a118, 2022 | | 2022 |
Michael J. MitchellAssociate Professor of Bioengineering, University of PennsylvaniaVerified email at seas.upenn.edu
