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Belén Rubio-Ruiz
Belén Rubio-Ruiz
Universidad de Granada, Departamento de Química Farmacéutica y Orgánica
Verified email at ugr.es
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Cited by
Cited by
Year
Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum
NMB Brancucci, JP Gerdt, CQ Wang, M De Niz, N Philip, SR Adapa, ...
Cell 171 (7), 1532-1544. e15, 2017
2942017
Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis
M Sancho-Albero, B Rubio-Ruiz, AM Pérez-López, V Sebastián, ...
Nature catalysis 2 (10), 864-872, 2019
2242019
Gold‐triggered uncaging chemistry in living systems
AM Pérez‐López, B Rubio‐Ruiz, V Sebastián, L Hamilton, C Adam, ...
Angewandte Chemie International Edition 56 (41), 12548-12552, 2017
1542017
Efficient palladium-triggered release of vorinostat from a bioorthogonal precursor
B Rubio-Ruiz, JT Weiss, A Unciti-Broceta
Journal of Medicinal Chemistry 59 (21), 9974-9980, 2016
1102016
Bright insights into palladium-triggered local chemotherapy
TL Bray, M Salji, A Brombin, AM Pérez-López, B Rubio-Ruiz, ...
Chemical Science 9 (37), 7354-7361, 2018
822018
Bioorthogonal uncaging of the active metabolite of irinotecan by palladium‐functionalized microdevices
C Adam, AM Pérez‐López, L Hamilton, B Rubio‐Ruiz, TL Bray, D Sieger, ...
Chemistry–A European Journal 24 (63), 16783-16790, 2018
552018
The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor
M Sahún‐Roncero, B Rubio‐Ruiz, G Saladino, A Conejo‐García, ...
Angewandte Chemie International Edition 52 (17), 4582-4586, 2013
472013
Effects of indomethacin, nimesulide, and diclofenac on human MG-63 osteosarcoma cell line
L Díaz-Rodríguez, O García-Martínez, MA Morales, L Rodríguez-Pérez, ...
Biological research for nursing 14 (1), 98-107, 2012
452012
Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action
JM Hearn, GM Hughes, I Romero-Canelón, AF Munro, B Rubio-Ruiz, ...
Metallomics 10 (1), 93-107, 2018
412018
High-precision photothermal ablation using biocompatible palladium nanoparticles and laser scanning microscopy
B Rubio-Ruiz, AM Pérez-López, TL Bray, M Lee, A Serrels, M Prieto, ...
ACS applied materials & interfaces 10 (4), 3341-3348, 2018
372018
Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death
L Serrán-Aguilera, H Denton, B Rubio-Ruiz, B López-Gutiérrez, A Entrena, ...
Scientific reports 6 (1), 33189, 2016
372016
N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture
JT Weiss, C Fraser, B Rubio-Ruiz, SH Myers, R Crispin, JC Dawson, ...
Frontiers in Chemistry 2, 56, 2014
352014
Bioorthogonal uncaging of cytotoxic paclitaxel through Pd nanosheet–hydrogel frameworks
AM Pérez-López, B Rubio-Ruiz, T Valero, R Contreras-Montoya, ...
Journal of Medicinal Chemistry 63 (17), 9650-9659, 2020
342020
Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors
B Rubio-Ruíz, A Conejo-García, P Ríos-Marco, MP Carrasco-Jiménez, ...
European journal of medicinal chemistry 50, 154-162, 2012
332012
Discovery of a new binding site on human choline kinase α1: design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives
B Rubio-Ruiz, A Figuerola-Conchas, J Ramos-Torrecillas, ...
Journal of medicinal chemistry 57 (2), 507-515, 2014
292014
Effect of acetaminophen (paracetamol) on human osteosarcoma cell line MG63
L Díaz-Rodríguez, O García-Martínez, M Arroyo-Morales, B Rubio-Ruiz, ...
Acta Pharmacologica Sinica 31 (11), 1495-1499, 2010
272010
Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies
M SAHUN RONCERO, B Rubio Ruíz, A Conejo García, ...
ChemBioChem 14 (11), 1291-1295, 2013
252013
A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo
C Adam, TL Bray, AM Pérez-López, EH Tan, B Rubio-Ruiz, DJ Baillache, ...
Journal of Medicinal Chemistry 65 (1), 552-561, 2022
222022
Recent advances in the design of choline kinase α inhibitors and the molecular basis of their inhibition
B Rubio‐Ruiz, L Serrán‐Aguilera, R Hurtado‐Guerrero, A Conejo‐García
Medicinal Research Reviews 41 (2), 902-927, 2021
182021
Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents
C Torres-Sánchez, AM Pérez-López, MN Alqahtani, A Unciti-Broceta, ...
New Journal of Chemistry 43 (3), 1449-1458, 2019
182019
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