| Genome-wide mutational signatures of aristolochic acid and its application as a screening tool SL Poon, ST Pang, JR McPherson, W Yu, KK Huang, P Guan, WH Weng, ... Science translational medicine 5 (197), 197ra101-197ra101, 2013 | 313 | 2013 |
| Activation of transforming growth factor beta 1 signaling in gastric cancer-associated fibroblasts increases their motility, via expression of rhomboid 5 homolog 2, and ability … T Ishimoto, K Miyake, T Nandi, M Yashiro, N Onishi, KK Huang, SJ Lin, ... Gastroenterology 153 (1), 191-204. e16, 2017 | 197 | 2017 |
| Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer V Kumar, K Ramnarayanan, R Sundar, N Padmanabhan, S Srivastava, ... Cancer discovery 12 (3), 670-691, 2022 | 194 | 2022 |
| Genomic and epigenomic profiling of high-risk intestinal metaplasia reveals molecular determinants of progression to gastric cancer KK Huang, K Ramnarayanan, F Zhu, S Srivastava, C Xu, ALK Tan, M Lee, ... Cancer cell 33 (1), 137-150. e5, 2018 | 188 | 2018 |
| Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance AL Vettore, K Ramnarayanan, G Poore, K Lim, CK Ong, KK Huang, ... Genome medicine 7, 1-15, 2015 | 85 | 2015 |
| Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma A Okabe, KK Huang, K Matsusaka, M Fukuyo, M Xing, X Ong, T Hoshii, ... Nature Genetics 52 (9), 919-930, 2020 | 70 | 2020 |
| Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer KK Huang, J Huang, JKL Wu, M Lee, ST Tay, V Kumar, K Ramnarayanan, ... Genome biology 22, 1-24, 2021 | 61 | 2021 |
| SETD2 histone modifier loss in aggressive GI stromal tumours KK Huang, JR McPherson, ST Tay, K Das, IB Tan, CCY Ng, NY Chia, ... Gut 65 (12), 1960-1972, 2016 | 54 | 2016 |
| Epigenomic promoter alterations predict for benefit from immune checkpoint inhibition in metastatic gastric cancer R Sundar, KK Huang, A Qamra, KM Kim, ST Kim, WK Kang, ALK Tan, ... Annals of Oncology 30 (3), 424-430, 2019 | 49 | 2019 |
| The Glaciozyma antarctica genome reveals an array of systems that provide sustained responses towards temperature variations in a persistently cold habitat M Firdaus-Raih, NHF Hashim, I Bharudin, MF Abu Bakar, KK Huang, ... PLoS One 13 (1), e0189947, 2018 | 48 | 2018 |
| Acquired resistance to FGFR inhibitor in diffuse-type gastric cancer through an AKT-independent PKC-mediated phosphorylation of GSK3β WM Lau, E Teng, KK Huang, JW Tan, K Das, Z Zang, T Chia, M Teh, ... Molecular cancer therapeutics 17 (1), 232-242, 2018 | 47 | 2018 |
| Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck KK Huang, KW Jang, S Kim, HS Kim, SM Kim, HJ Kwon, HR Kim, HJ Yun, ... Scientific reports 6 (1), 19552, 2016 | 38 | 2016 |
| HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer C Xu, WF Ooi, A Qamra, J Tan, BYJ Chua, SWT Ho, K Das, ZFA Isa, Z Li, ... Gut 69 (2), 231-242, 2020 | 33 | 2020 |
| Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition R Sundar, KK Huang, V Kumar, K Ramnarayanan, D Demircioglu, Z Her, ... Gut 71 (7), 1277-1288, 2022 | 25 | 2022 |
| CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies R Davies, L Liu, S Taotao, N Tuano, R Chaturvedi, KK Huang, C Itman, ... Genome biology 22, 1-19, 2021 | 15 | 2021 |
| Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer M Xing, WF Ooi, J Tan, A Qamra, PH Lee, Z Li, C Xu, N Padmanabhan, ... The Journal of clinical investigation 130 (6), 3005-3020, 2020 | 15 | 2020 |
| Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation N Padmanabhan, HK Kyon, A Boot, K Lim, S Srivastava, S Chen, Z Wu, ... Genome biology 22, 1-29, 2021 | 14 | 2021 |
| DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia V Krishnan, DXE Lim, PM Hoang, S Srivastava, J Matsuo, KK Huang, ... Gut 69 (10), 1738-1749, 2020 | 14 | 2020 |
| Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ... Gut 72 (2), 226-241, 2023 | 13 | 2023 |
| Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression KK Huang, H Ma, RHH Chong, T Uchihara, BSX Lian, F Zhu, T Sheng, ... Cancer cell 41 (12), 2019-2037. e8, 2023 | 11 | 2023 |
