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David Lodowski
David Lodowski
Assistant Professor Center for Proteomics and Bioinformatics, Case Western Reserve University
Verified email at case.edu - Homepage
Title
Cited by
Cited by
Year
Microbial and animal rhodopsins: structures, functions, and molecular mechanisms
OP Ernst, DT Lodowski, M Elstner, P Hegemann, LS Brown, H Kandori
Chemical reviews 114 (1), 126-163, 2014
11052014
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
D Salom, DT Lodowski, RE Stenkamp, IL Trong, M Golczak, ...
Proceedings of the National Academy of Sciences 103 (44), 16123-16128, 2006
5362006
Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gßγ
DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer
Science 300 (5623), 1256-1262, 2003
4622003
The significance of G protein-coupled receptor crystallography for drug discovery
JA Salon, DT Lodowski, K Palczewski
Pharmacological reviews 63 (4), 901-937, 2011
2622011
Structure of the full-length TRPV2 channel by cryo-EM
KW Huynh, MR Cohen, J Jiang, A Samanta, DT Lodowski, ZH Zhou, ...
Nature communications 7 (1), 11130, 2016
2082016
Assembly of a GPCR-G protein complex
Y Du, NM Duc, SGF Rasmussen, D Hilger, X Kubiak, L Wang, J Bohon, ...
Cell 177 (5), 1232-1242. e11, 2019
1862019
Activation of G protein–coupled receptors: beyond two-state models and tertiary conformational changes
PSH Park, DT Lodowski, K Palczewski
Annu. Rev. Pharmacol. Toxicol. 48, 107-141, 2008
1832008
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle
PD Kiser, M Golczak, DT Lodowski, MR Chance, K Palczewski
Proceedings of the National Academy of Sciences 106 (41), 17325-17330, 2009
1612009
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1
N Mast, AJ Annalora, DT Lodowski, K Palczewski, CD Stout, IA Pikuleva
Journal of biological chemistry 286 (7), 5607-5613, 2011
1392011
The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs
DT Lodowski, VM Tesmer, JL Benovic, JJG Tesmer
Journal of Biological Chemistry 281 (24), 16785-16793, 2006
1222006
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
TET Hughes, DT Lodowski, KW Huynh, A Yazici, J Del Rosario, A Kapoor, ...
Nature structural & molecular biology 25 (1), 53-60, 2018
1172018
Structural basis for the acyltransferase activity of lecithin: retinol acyltransferase-like proteins
M Golczak, PD Kiser, AE Sears, DT Lodowski, WS Blaner, K Palczewski
Journal of biological chemistry 287 (28), 23790-23807, 2012
822012
Chemokine receptors and other G protein-coupled receptors
DT Lodowski, K Palczewski
Current opinion in HIV and AIDS 4 (2), 88-95, 2009
802009
Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol
JJG Tesmer, VM Tesmer, DT Lodowski, H Steinhagen, J Huber
Journal of medicinal chemistry 53 (4), 1867-1870, 2010
752010
Importance of membrane structural integrity for RPE65 retinoid isomerization activity
M Golczak, PD Kiser, DT Lodowski, A Maeda, K Palczewski
Journal of biological chemistry 285 (13), 9667-9682, 2010
742010
The role of Gβγ and domain interfaces in the activation of G protein-coupled receptor kinase 2
DT Lodowski, JF Barnhill, RM Pyskadlo, R Ghirlando, R Sterne-Marr, ...
Biochemistry 44 (18), 6958-6970, 2005
692005
Comparative Analysis of GPCR Crystal Structures
DT Lodowski, TE Angel, K Palczewski
Photochemistry and photobiology 85 (2), 425-430, 2009
672009
Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals
D Salom, I Le Trong, E Pohl, JA Ballesteros, RE Stenkamp, K Palczewski, ...
Journal of structural biology 156 (3), 497-504, 2006
652006
Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations
W Sun, C Gerth, A Maeda, DT Lodowski, L Van Der Kraak, DA Saperstein, ...
Vision research 47 (15), 2055-2066, 2007
612007
Rhodopsin–transducin heteropentamer: Three-dimensional structure and biochemical characterization
B Jastrzebska, P Ringler, DT Lodowski, V Moiseenkova-Bell, M Golczak, ...
Journal of structural biology 176 (3), 387-394, 2011
602011
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