| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13142* | 2021 |
| Regulation of androgen receptor activity by tyrosine phosphorylation Z Guo, B Dai, T Jiang, K Xu, Y Xie, O Kim, I Nesheiwat, X Kong, ... Cancer cell 10 (4), 309-319, 2006 | 450 | 2006 |
| Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development RD Bruno, VCO Njar Bioorganic & medicinal chemistry 15 (15), 5047-5060, 2007 | 345 | 2007 |
| Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate … VD Handratta, TS Vasaitis, VCO Njar, LK Gediya, R Kataria, P Chopra, ... Journal of medicinal chemistry 48 (8), 2972-2984, 2005 | 330 | 2005 |
| CYP17 inhibitors for prostate cancer therapy TS Vasaitis, RD Bruno, VCO Njar The Journal of steroid biochemistry and molecular biology 125 (1-2), 23-31, 2011 | 255 | 2011 |
| Promise and challenges in drug discovery and development of hybrid anticancer drugs LK Gediya, VCO Njar Expert opinion on drug discovery 4 (11), 1099-1111, 2009 | 225 | 2009 |
| Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer VCO Njar, AMH Brodie Journal of medicinal chemistry 58 (5), 2077-2087, 2015 | 213 | 2015 |
| Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases VCO Njar, L Gediya, P Purushottamachar, P Chopra, TS Vasaitis, ... Bioorganic & medicinal chemistry 14 (13), 4323-4340, 2006 | 205 | 2006 |
| Mechanistic studies on aromatase and related C C bond cleaving P-450 enzymes M Akhtar, VCO Njar, JN Wright The Journal of steroid biochemistry and molecular biology 44 (4-6), 375-387, 1993 | 194 | 1993 |
| Androgen receptor inactivation contributes to antitumor efficacy of 17α-hydroxylase/17,20-lyase inhibitor 3β-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16 … T Vasaitis, A Belosay, A Schayowitz, A Khandelwal, P Chopra, LK Gediya, ... Molecular cancer therapeutics 7 (8), 2348-2357, 2008 | 169 | 2008 |
| Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17α-hydroxylase-C17, 20-lyase (P45017α): potential agents for the treatment of prostate cancer VCO Njar, K Kato, IP Nnane, DN Grigoryev, BJ Long, AMH Brodie Journal of medicinal chemistry 41 (6), 902-912, 1998 | 165 | 1998 |
| Aromatase inhibitors and their application in breast cancer treatment☆ AMH Brodie, VCO Njar Steroids 65 (4), 171-179, 2000 | 162 | 2000 |
| A new simple and high-yield synthesis of suberoylanilide hydroxamic acid and its inhibitory effect alone or in combination with retinoids on proliferation of human prostate … LK Gediya, P Chopra, P Purushottamachar, N Maheshwari, VCO Njar Journal of medicinal chemistry 48 (15), 5047-5051, 2005 | 131 | 2005 |
| Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy OO Clement, CM Freeman, RW Hartmann, VD Handratta, TS Vasaitis, ... Journal of medicinal chemistry 46 (12), 2345-2351, 2003 | 129 | 2003 |
| Inhibitors of 170-Hydroxylase/17, 20-Lyase (CYP17): Potential Agents for V Njar, A Brodie Current pharmaceutical design 5 (3), 163, 1999 | 128 | 1999 |
| Systematic structure modifications of multitarget prostate cancer drug candidate galeterone to produce novel androgen receptor down-regulating agents as an approach to … P Purushottamachar, AM Godbole, LK Gediya, MS Martin, TS Vasaitis, ... Journal of medicinal chemistry 56 (12), 4880-4898, 2013 | 126 | 2013 |
| Comprehensive pharmacology and clinical efficacy of aromatase inhibitors VCO Njar, AMH Brodie Drugs 58, 233-255, 1999 | 124 | 1999 |
| Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate … AK Kwegyir-Afful, S Ramalingam, P Purushottamachar, VP Ramamurthy, ... Oncotarget 6 (29), 27440, 2015 | 116 | 2015 |
| Aromatase inhibitors in advanced breast cancer: mechanism of action and clinical implications AMH Brodie, VCO Njar The Journal of steroid biochemistry and molecular biology 66 (1-2), 1-10, 1998 | 114 | 1998 |
| Methyl angolensate: the antiulcer agent of the stem bark of Entandrophragma angolense VCO Njar, JK Adesanwo, Y Raji Planta medica 61 (01), 91-92, 1995 | 108 | 1995 |
Lalji GediyaResearch AssociateVerified email at som.umaryland.edu
