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Paul S Kelly
Paul S Kelly
National Institute for Bioprocessing Research and Training
Verified email at nibrt.ie
Title
Cited by
Cited by
Year
Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate
C Clarke, M Henry, P Doolan, S Kelly, S Aherne, N Sanchez, P Kelly, ...
BMC genomics 13, 1-14, 2012
1012012
MicroRNAs: tiny targets for engineering CHO cell phenotypes?
N Barron, N Sanchez, P Kelly, M Clynes
Biotechnology letters 33, 11-21, 2011
812011
CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR‐7 activity via sponge decoy vectors
N Sanchez, P Kelly, C Gallagher, NT Lao, C Clarke, M Clynes, N Barron
Biotechnology journal 9 (3), 396-404, 2014
562014
Re‐programming CHO cell metabolism using miR‐23 tips the balance towards a highly productive phenotype
PS Kelly, L Breen, C Gallagher, S Kelly, M Henry, NT Lao, P Meleady, ...
Biotechnology Journal 10 (7), 1029-1040, 2015
522015
Conserved microRNA function as a basis for Chinese hamster ovary cell engineering
PS Kelly, C Gallagher, M Clynes, N Barron
Biotechnology letters 37, 787-798, 2015
362015
Process‐relevant concentrations of the leachable b D t BPP impact negatively on C HO cell production characteristics
PS Kelly, S McSweeney, O Coleman, S Carillo, M Henry, D Chandran, ...
Biotechnology progress 32 (6), 1547-1558, 2016
252016
Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells
PS Kelly, C Clarke, A Costello, C Monger, J Meiller, H Dhiman, N Borth, ...
Metabolic engineering 41, 11-22, 2017
242017
Towards next generation CHO cell biology: Bioinformatics methods for RNA‐Seq‐based expression profiling
C Monger, PS Kelly, C Gallagher, M Clynes, N Barron, C Clarke
Biotechnology Journal 10 (7), 950-966, 2015
222015
Selection of high-producing clones using FACS for CHO cell line development
C Gallagher, PS Kelly
Heterologous Protein Production in CHO Cells: Methods and Protocols, 143-152, 2017
152017
From media to mitochondria–rewiring cellular energy metabolism of Chinese hamster ovary cells for the enhanced production of biopharmaceuticals
PS Kelly, AA Miguez, C Alves, N Barron
Current opinion in chemical engineering 22, 71-80, 2018
142018
Improvements in single‐use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance
PS Kelly, N Dorival‐García, S Paré, S Carillo, C Ta, A Alarcon Miguez, ...
Biotechnology Progress 35 (4), e2824, 2019
122019
miR‐CATCH Identifies Biologically Active miRNA Regulators of the Pro‐Survival Gene XIAP, in Chinese Hamster Ovary Cells
A Griffith, PS Kelly, S Vencken, NT Lao, CM Greene, M Clynes, N Barron
Biotechnology Journal 13 (3), 1700299, 2018
112018
Bioprocess engineering: micromanaging Chinese hamster ovary cell phenotypes
PS Kelly, C Clarke, M Clynes, N Barron
Pharmaceutical Bioprocessing 2 (4), 323-337, 2014
112014
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells
I Tzani, C Monger, K Motheramgari, C Gallagher, R Hagan, P Kelly, ...
Biotechnology and Bioengineering 117 (8), 2489-2503, 2020
72020
Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling
I Tzani, C Monger, P Kelly, N Barron, RM Kelly, C Clarke
Current opinion in biotechnology 53, 182-190, 2018
72018
Enhancing CHO cell productivity through the stable depletion of microRNA-23
PS Kelly
Dublin City University, 2014
22014
Radiation curing coating composition
V Maurin, P Kelly
US Patent 10,167,359, 2019
12019
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity
M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ...
2022
Found in translation: Microproteins are a new class of potential host cell impurity in mAb drug products
M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ...
bioRxiv, 2022.01. 20.475618, 2022
2022
miR-CATCH identifies biologically active miRNA regulators of the pro-survival gene XIAP, in Chinese hamster ovary cells
PS Kelly, A Griffith, S Vencken, NT Lao, M Clynes, N Barron
2018
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