Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate C Clarke, M Henry, P Doolan, S Kelly, S Aherne, N Sanchez, P Kelly, ... BMC genomics 13, 1-14, 2012 | 101 | 2012 |
MicroRNAs: tiny targets for engineering CHO cell phenotypes? N Barron, N Sanchez, P Kelly, M Clynes Biotechnology letters 33, 11-21, 2011 | 81 | 2011 |
CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR‐7 activity via sponge decoy vectors N Sanchez, P Kelly, C Gallagher, NT Lao, C Clarke, M Clynes, N Barron Biotechnology journal 9 (3), 396-404, 2014 | 56 | 2014 |
Re‐programming CHO cell metabolism using miR‐23 tips the balance towards a highly productive phenotype PS Kelly, L Breen, C Gallagher, S Kelly, M Henry, NT Lao, P Meleady, ... Biotechnology Journal 10 (7), 1029-1040, 2015 | 52 | 2015 |
Conserved microRNA function as a basis for Chinese hamster ovary cell engineering PS Kelly, C Gallagher, M Clynes, N Barron Biotechnology letters 37, 787-798, 2015 | 36 | 2015 |
Process‐relevant concentrations of the leachable b D t BPP impact negatively on C HO cell production characteristics PS Kelly, S McSweeney, O Coleman, S Carillo, M Henry, D Chandran, ... Biotechnology progress 32 (6), 1547-1558, 2016 | 25 | 2016 |
Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells PS Kelly, C Clarke, A Costello, C Monger, J Meiller, H Dhiman, N Borth, ... Metabolic engineering 41, 11-22, 2017 | 24 | 2017 |
Towards next generation CHO cell biology: Bioinformatics methods for RNA‐Seq‐based expression profiling C Monger, PS Kelly, C Gallagher, M Clynes, N Barron, C Clarke Biotechnology Journal 10 (7), 950-966, 2015 | 22 | 2015 |
Selection of high-producing clones using FACS for CHO cell line development C Gallagher, PS Kelly Heterologous Protein Production in CHO Cells: Methods and Protocols, 143-152, 2017 | 15 | 2017 |
From media to mitochondria–rewiring cellular energy metabolism of Chinese hamster ovary cells for the enhanced production of biopharmaceuticals PS Kelly, AA Miguez, C Alves, N Barron Current opinion in chemical engineering 22, 71-80, 2018 | 14 | 2018 |
Improvements in single‐use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance PS Kelly, N Dorival‐García, S Paré, S Carillo, C Ta, A Alarcon Miguez, ... Biotechnology Progress 35 (4), e2824, 2019 | 12 | 2019 |
miR‐CATCH Identifies Biologically Active miRNA Regulators of the Pro‐Survival Gene XIAP, in Chinese Hamster Ovary Cells A Griffith, PS Kelly, S Vencken, NT Lao, CM Greene, M Clynes, N Barron Biotechnology Journal 13 (3), 1700299, 2018 | 11 | 2018 |
Bioprocess engineering: micromanaging Chinese hamster ovary cell phenotypes PS Kelly, C Clarke, M Clynes, N Barron Pharmaceutical Bioprocessing 2 (4), 323-337, 2014 | 11 | 2014 |
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells I Tzani, C Monger, K Motheramgari, C Gallagher, R Hagan, P Kelly, ... Biotechnology and Bioengineering 117 (8), 2489-2503, 2020 | 7 | 2020 |
Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling I Tzani, C Monger, P Kelly, N Barron, RM Kelly, C Clarke Current opinion in biotechnology 53, 182-190, 2018 | 7 | 2018 |
Enhancing CHO cell productivity through the stable depletion of microRNA-23 PS Kelly Dublin City University, 2014 | 2 | 2014 |
Radiation curing coating composition V Maurin, P Kelly US Patent 10,167,359, 2019 | 1 | 2019 |
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ... | | 2022 |
Found in translation: Microproteins are a new class of potential host cell impurity in mAb drug products M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ... bioRxiv, 2022.01. 20.475618, 2022 | | 2022 |
miR-CATCH identifies biologically active miRNA regulators of the pro-survival gene XIAP, in Chinese hamster ovary cells PS Kelly, A Griffith, S Vencken, NT Lao, M Clynes, N Barron | | 2018 |