| Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling* 210 X Lin, M Liang, XH Feng Journal of Biological Chemistry 275 (47), 36818-36822, 2000 | 626 | 2000 |
| PPM1A functions as a Smad phosphatase to terminate TGFβ signaling X Lin, X Duan, YY Liang, Y Su, KH Wrighton, J Long, M Hu, CM Davis, ... Cell 125 (5), 915-928, 2006 | 607 | 2006 |
| Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF-β XH Feng, X Lin, R Derynck The EMBO journal 19 (19), 5178-5193, 2000 | 538 | 2000 |
| Phospho-control of TGF-β superfamily signaling KH Wrighton, X Lin, XH Feng Cell research 19 (1), 8-20, 2009 | 427 | 2009 |
| Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-β-mediated induction of the CDK inhibitor p15Ink4B XH Feng, YY Liang, M Liang, W Zhai, X Lin Molecular cell 9 (1), 133-143, 2002 | 336 | 2002 |
| Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding X Lin, B Sun, M Liang, YY Liang, A Gast, J Hildebrand, FC Brunicardi, ... Molecular cell 11 (5), 1389-1396, 2003 | 233 | 2003 |
| SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4 X Lin, M Liang, YY Liang, FC Brunicardi, XH Feng Journal of Biological Chemistry 278 (33), 31043-31048, 2003 | 222 | 2003 |
| A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. X Lin, DL Barber Proceedings of the National Academy of Sciences 93 (22), 12631-12636, 1996 | 215 | 1996 |
| Smad7 protein interacts with receptor-regulated Smads (R-Smads) to inhibit transforming growth factor-β (TGF-β)/Smad signaling X Yan, H Liao, M Cheng, X Shi, X Lin, XH Feng, YG Chen Journal of Biological Chemistry 291 (1), 382-392, 2016 | 203 | 2016 |
| COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis J Qin, SP Wu, CJ Creighton, F Dai, X Xie, CM Cheng, A Frolov, G Ayala, ... Nature 493 (7431), 236-240, 2013 | 199 | 2013 |
| Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β–dependent cancer metastasis J Xue, X Lin, WT Chiu, YH Chen, G Yu, M Liu, XH Feng, R Sawaya, ... The Journal of clinical investigation 124 (2), 564-579, 2014 | 194 | 2014 |
| Activation of transforming growth factor-β signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4 X Lin, M Liang, YY Liang, FC Brunicardi, F Melchior, XH Feng Journal of Biological Chemistry 278 (21), 18714-18719, 2003 | 192 | 2003 |
| Smad7-induced β-catenin degradation alters epidermal appendage development G Han, AG Li, YY Liang, P Owens, W He, S Lu, Y Yoshimatsu, D Wang, ... Developmental cell 11 (3), 301-312, 2006 | 182 | 2006 |
| Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ... The Journal of clinical investigation 128 (4), 1283-1299, 2018 | 178 | 2018 |
| Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein X Lin, RA Sikkink, F Rusnak, DL Barber Journal of Biological Chemistry 274 (51), 36125-36131, 1999 | 166 | 1999 |
| Transforming growth factor β can stimulate Smad1 phosphorylation independently of bone morphogenic protein receptors KH Wrighton, X Lin, BY Paul, XH Feng Journal of Biological Chemistry 284 (15), 9755-9763, 2009 | 164 | 2009 |
| Critical regulation of TGFβ signaling by Hsp90 KH Wrighton, X Lin, XH Feng Proceedings of the National Academy of Sciences 105 (27), 9244-9249, 2008 | 150 | 2008 |
| Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription X Lin, YY Liang, B Sun, M Liang, Y Shi, FC Brunicardi, Y Shi, XH Feng Molecular and cellular biology 23 (24), 9081-9093, 2003 | 140 | 2003 |
| Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling KH Wrighton, D Willis, J Long, F Liu, X Lin, XH Feng Journal of biological chemistry 281 (50), 38365-38375, 2006 | 128 | 2006 |
| Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway X Duan, YY Liang, XH Feng, X Lin Journal of biological chemistry 281 (48), 36526-36532, 2006 | 127 | 2006 |
