Progressive muscular dystrophy in α-sarcoglycan–deficient mice F Duclos, V Straub, SA Moore, DP Venzke, RF Hrstka, RH Crosbie, ... The Journal of cell biology 142 (6), 1461-1471, 1998 | 424 | 1998 |
Membrane targeting and stabilization of sarcospan is mediated by the sarcoglycan subcomplex RH Crosbie, CS Lebakken, KH Holt, DP Venzke, V Straub, JC Lee, ... The Journal of cell biology 145 (1), 153-165, 1999 | 206 | 1999 |
Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1 J Reiland, VL Ott, CS Lebakken, C Yeaman, J McCARTHY, ... Biochemical journal 319 (1), 39-47, 1996 | 130 | 1996 |
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion EH Nguyen, WT Daly, NNT Le, M Farnoodian, DG Belair, MP Schwartz, ... Nature biomedical engineering 1 (7), 0096, 2017 | 113 | 2017 |
Syndecan-1 mediates cell spreading in transfected human lymphoblastoid (Raji) cells. CS Lebakken, AC Rapraeger The Journal of cell biology 132 (6), 1209-1221, 1996 | 107 | 1996 |
Sarcospan-deficient mice maintain normal muscle function CS Lebakken, DP Venzke, RF Hrstka, CM Consolino, JA Faulkner, ... Molecular and cellular biology 20 (5), 1669-1677, 2000 | 99 | 2000 |
Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform CS Lebakken, SM Riddle, U Singh, WJ Frazee, HC Eliason, Y Gao, ... SLAS Discovery 14 (8), 924-935, 2009 | 97 | 2009 |
LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status A Reynolds, EA Doggett, SM Riddle, CS Lebakken, RJ Nichols Frontiers in molecular neuroscience 7, 54, 2014 | 81 | 2014 |
Elevated levels of syndecan-1 expression confer potent serum-dependent growth in human 293T cells F Numa, K Hirabashi, N Tsunaga, H Kato, K O'Rourke, S Haining, ... Cancer research 55 (20), 4676-4680, 1995 | 65 | 1995 |
Analysis of ligand-dependent recruitment of coactivator peptides to estrogen receptor using fluorescence polarization MS Ozers, KM Ervin, CL Steffen, JA Fronczak, CS Lebakken, ... Molecular Endocrinology 19 (1), 25-34, 2005 | 57 | 2005 |
Sarcoglycan complex: implications for metabolic defects in muscular dystrophies S Groh, H Zong, MM Goddeeris, CS Lebakken, D Venzke, JE Pessin, ... Journal of biological chemistry 284 (29), 19178-19182, 2009 | 54 | 2009 |
A fluorescence lifetime–based binding assay to characterize kinase inhibitors CS Lebakken, HC Kang, KW Vogel SLAS Discovery 12 (6), 828-841, 2007 | 51 | 2007 |
A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate BD Marks, RW Smith, HA Braun, TA Goossens, M Christenson, MS Ozers, ... Assay and drug development technologies 1 (1), 73-81, 2002 | 40 | 2002 |
High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells Y Iwata, WD Klaren, CS Lebakken, FA Grimm, I Rusyn Assay and drug development technologies 15 (6), 267-279, 2017 | 32 | 2017 |
Syndecan-1 signals independently of β1 integrins during Raji cell spreading CS Lebakken, KJ McQuade, AC Rapraeger Experimental Cell Research 259 (2), 315-325, 2000 | 32 | 2000 |
High-Throughput screeening assays for CYP2B6 metabolism and inhibition usuing fluorogenic vivid substrates BD Marks, TA Goossens, HA Braun, MS Ozers, RW Smith, C Lebakken, ... Aaps Pharmsci 5 (2), 18, 2003 | 20 | 2003 |
Detection of allosteric kinase inhibitors by displacement of active site probes CS Lebakken, LJ Reichling, JM Ellefson, SM Riddle Journal of Biomolecular Screening 17 (6), 813-821, 2012 | 18 | 2012 |
Multi-pathway cellular analysis of compound selectivity MK Hancock, CS Lebakken, J Wang, K Bi Molecular BioSystems 6 (10), 1834-1843, 2010 | 18 | 2010 |
Sarcospan-deficient mouse as a model for clinical disorders associated with sarcospan mutations KP Campbell, C Lebakken, R Crosbie, R Williamson US Patent 6,207,878, 2001 | 16 | 2001 |
An improved β-lactamase reporter assay: multiplexing with a cytotoxicity readout for enhanced accuracy of hit identification TM Hallis, AL Kopp, J Gibson, CS Lebakken, M Hancock, ... Journal of biomolecular screening 12 (5), 635-644, 2007 | 15 | 2007 |