Metabolic regulation is important for spermatogenesis L Rato, MG Alves, S Socorro, AI Duarte, JE Cavaco, PF Oliveira Nature Reviews Urology 9 (6), 330-338, 2012 | 479 | 2012 |
Insulin in central nervous system: more than just a peripheral hormone AI Duarte, PI Moreira, CR Oliveira Journal of aging research 2012, 2012 | 371 | 2012 |
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease PI Moreira, AI Duarte, MS Santos, AC Rego, CR Oliveira Journal of Alzheimer's Disease 16 (4), 741-761, 2009 | 247 | 2009 |
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3β signaling pathways and changes in protein expression AI Duarte, P Santos, CR Oliveira, MS Santos, AC Rego Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (6), 994-1002, 2008 | 177 | 2008 |
Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration AI Duarte, E Candeias, SC Correia, RX Santos, C Carvalho, S Cardoso, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (4), 527-541, 2013 | 175 | 2013 |
Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress L Rato, AI Duarte, GD Tomás, MS Santos, PI Moreira, S Socorro, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (3), 335-344, 2014 | 152 | 2014 |
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes S Correia, C Carvalho, MS Santos, T Proença, E Nunes, AI Duarte, ... Medicinal chemistry 4 (4), 358-364, 2008 | 146 | 2008 |
The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease AI Plácido, CMF Pereira, AI Duarte, E Candeias, SC Correia, RX Santos, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014 | 129 | 2014 |
Insulin as a bridge between type 2 diabetes and Alzheimer disease–how anti-diabetics could be a solution for dementia I Sebastião, E Candeias, MS Santos, CR de Oliveira, PI Moreira, ... Frontiers in endocrinology 5, 97029, 2014 | 113 | 2014 |
Insulin neuroprotection against oxidative stress in cortical neurons—involvement of uric acid and glutathione antioxidant defenses AI Duarte, MS Santos, CR Oliveira, AC Rego Free Radical Biology and Medicine 39 (7), 876-889, 2005 | 113 | 2005 |
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress AI Duarte, T Proença, CR Oliveira, MS Santos, AC Rego Diabetes 55 (10), 2863-2870, 2006 | 110 | 2006 |
Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide EM Candeias, IC Sebastião, SM Cardoso, SC Correia, CI Carvalho, ... World journal of diabetes 6 (6), 807, 2015 | 107 | 2015 |
The impairment of insulin signaling in Alzheimer's disease E Candeias, AI Duarte, C Carvalho, SC Correia, S Cardoso, RX Santos, ... IUBMB life, 2012 | 105 | 2012 |
Synaptosomal response to oxidative stress: effect of vinpocetine MS Santos, AI Duarte, PI Moreira, CR Oliveira Free radical research 32 (1), 57-66, 2000 | 93 | 2000 |
Brain GLP-1/IGF-1 signaling and autophagy mediate exendin-4 protection against apoptosis in type 2 diabetic rats E Candeias, I Sebastião, S Cardoso, C Carvalho, MS Santos, CR Oliveira, ... Molecular neurobiology 55, 4030-4050, 2018 | 84 | 2018 |
Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells L Rato, MG Alves, AI Duarte, MS Santos, PI Moreira, JE Cavaco, ... The international journal of biochemistry & cell biology 66, 1-10, 2015 | 79 | 2015 |
Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington’s Disease human lymphoblasts L Naia, IL Ferreira, T Cunha-Oliveira, AI Duarte, M Ribeiro, ... Molecular neurobiology 51, 331-348, 2015 | 77 | 2015 |
Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease-from clinical features to the bench T R Rosenstock, A I Duarte, A Cristina Rego Current drug targets 11 (10), 1218-1236, 2010 | 74 | 2010 |
IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice C Lopes, M Ribeiro, AI Duarte, S Humbert, F Saudou, ... Molecular neurobiology 49, 1126-1142, 2014 | 73 | 2014 |
Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia P Monteiro, AI Duarte, LM Gonçalves, A Moreno, LA Providência European journal of pharmacology 503 (1-3), 123-128, 2004 | 73 | 2004 |