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Angad P. Mehta
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Anaerobic biosynthesis of the lower ligand of vitamin B12
AB Hazra, AW Han, AP Mehta, KC Mok, V Osadchiy, TP Begley, ME Taga
Proceedings of the National Academy of Sciences 112 (34), 10792-10797, 2015
1192015
Radical SAM Enzymes in Cofactor Biosynthesis: a treasure trove of complex organic radical rearrangement reactions
AP Mehta, S Abdelwahed, N Mahanta, D Fedoseyenko, B Philmus, ...
Journal of Biological Chemistry, jbc. R114. 623793, 2014
75*2014
Catalysis of a new ribose carbon-insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA
AP Mehta, JW Hanes, SH Abdelwahed, DG Hilmey, P Hänzelmann, ...
Biochemistry 52 (7), 1134-1136, 2013
572013
Enhancing protein stability with genetically encoded noncanonical amino acids
JC Li, T Liu, Y Wang, AP Mehta, PG Schultz
Journal of the American Chemical Society 140 (47), 15997-16000, 2018
532018
Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids
C Zambaldo, X Luo, AP Mehta, PG Schultz
Journal of the american chemical society 139 (34), 11646-11649, 2017
442017
Engineering yeast endosymbionts as a step toward the evolution of mitochondria
AP Mehta, L Supekova, JH Chen, K Pestonjamasp, P Webster, Y Ko, ...
Proceedings of the National Academy of Sciences 115 (46), 11796-11801, 2018
412018
Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase
MK Fenwick, AP Mehta, Y Zhang, SH Abdelwahed, TP Begley, SE Ealick
Nature communications 6 (1), 6480, 2015
342015
Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B12 Biosynthesis
AP Mehta, SH Abdelwahed, MK Fenwick, AB Hazra, ME Taga, Y Zhang, ...
Journal of the American Chemical Society 137 (33), 10444-10447, 2015
332015
Molybdopterin biosynthesis: trapping an unusual purine ribose adduct in the MoaA-catalyzed reaction
AP Mehta, SH Abdelwahed, TP Begley
Journal of the American Chemical Society 135 (30), 10883-10885, 2013
322013
Molybdopterin biosynthesis: Trapping of intermediates for the MoaA-catalyzed reaction using 2′-deoxyGTP and 2′-chloroGTP as substrate analogues.
AP Mehta, SH Abdelwahed, H Xu, TP Begley
Journal of the American Chemical Society 136 (30), 10609-10614, 2014
282014
High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana
S Coquille, C Roux, A Mehta, TP Begley, TB Fitzpatrick, S Thore
Journal of structural biology 184 (3), 438-444, 2013
242013
Replacement of 2′-Deoxycytidine by 2′-Deoxycytidine Analogues in the E. coli Genome
AP Mehta, H Li, SA Reed, L Supekova, T Javahishvili, PG Schultz
Journal of the American Chemical Society 138 (43), 14230-14233, 2016
222016
Replacement of Thymidine by a Modified Base in the Escherichia coli Genome
AP Mehta, H Li, SA Reed, L Supekova, T Javahishvili, PG Schultz
Journal of the American Chemical Society 138 (23), 7272-7275, 2016
202016
Identification of the first riboflavin catabolic gene cluster isolated from Microbacterium maritypicum G10
H Xu, Y Chakrabarty, B Philmus, AP Mehta, D Bhandari, HP Hohmann, ...
Journal of Biological Chemistry 291 (45), 23506-23515, 2016
182016
Engineering artificial photosynthetic life-forms through endosymbiosis
JE Cournoyer, SD Altman, Y Gao, CL Wallace, D Zhang, GH Lo, ...
Nature communications 13 (1), 2254, 2022
162022
An aminoimidazole radical intermediate in the anaerobic biosynthesis of the 5, 6-dimethylbenzimidazole ligand to vitamin B12
DM Gagnon, TA Stich, AP Mehta, SH Abdelwahed, TP Begley, RD Britt
Journal of the American Chemical Society 140 (40), 12798-12807, 2018
122018
Toward a synthetic yeast endosymbiont with a minimal genome
AP Mehta, Y Ko, L Supekova, K Pestonjamasp, J Li, PG Schultz
Journal of the American Chemical Society 141 (35), 13799-13802, 2019
102019
Bacterial genome containing chimeric DNA–RNA sequences
AP Mehta, Y Wang, SA Reed, L Supekova, T Javahishvili, JC Chaput, ...
Journal of the American Chemical Society 140 (36), 11464-11473, 2018
92018
Molybdopterin biosynthesis—Mechanistic studies on a novel MoaA catalyzed insertion of a purine carbon into the ribose of GTP
AP Mehta, SH Abdelwahed, TP Begley
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (9), 1073-1077, 2015
72015
Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes
MY Ornelas, AY Thomas, LI Johnson Rosas, RO Scoville, AP Mehta
ACS synthetic biology 11 (11), 3759-3771, 2022
32022
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Articles 1–20