Anaerobic biosynthesis of the lower ligand of vitamin B12 AB Hazra, AW Han, AP Mehta, KC Mok, V Osadchiy, TP Begley, ME Taga Proceedings of the National Academy of Sciences 112 (34), 10792-10797, 2015 | 119 | 2015 |
Radical SAM Enzymes in Cofactor Biosynthesis: a treasure trove of complex organic radical rearrangement reactions AP Mehta, S Abdelwahed, N Mahanta, D Fedoseyenko, B Philmus, ... Journal of Biological Chemistry, jbc. R114. 623793, 2014 | 75* | 2014 |
Catalysis of a new ribose carbon-insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA AP Mehta, JW Hanes, SH Abdelwahed, DG Hilmey, P Hänzelmann, ... Biochemistry 52 (7), 1134-1136, 2013 | 57 | 2013 |
Enhancing protein stability with genetically encoded noncanonical amino acids JC Li, T Liu, Y Wang, AP Mehta, PG Schultz Journal of the American Chemical Society 140 (47), 15997-16000, 2018 | 53 | 2018 |
Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids C Zambaldo, X Luo, AP Mehta, PG Schultz Journal of the american chemical society 139 (34), 11646-11649, 2017 | 44 | 2017 |
Engineering yeast endosymbionts as a step toward the evolution of mitochondria AP Mehta, L Supekova, JH Chen, K Pestonjamasp, P Webster, Y Ko, ... Proceedings of the National Academy of Sciences 115 (46), 11796-11801, 2018 | 41 | 2018 |
Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase MK Fenwick, AP Mehta, Y Zhang, SH Abdelwahed, TP Begley, SE Ealick Nature communications 6 (1), 6480, 2015 | 34 | 2015 |
Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B12 Biosynthesis AP Mehta, SH Abdelwahed, MK Fenwick, AB Hazra, ME Taga, Y Zhang, ... Journal of the American Chemical Society 137 (33), 10444-10447, 2015 | 33 | 2015 |
Molybdopterin biosynthesis: trapping an unusual purine ribose adduct in the MoaA-catalyzed reaction AP Mehta, SH Abdelwahed, TP Begley Journal of the American Chemical Society 135 (30), 10883-10885, 2013 | 32 | 2013 |
Molybdopterin biosynthesis: Trapping of intermediates for the MoaA-catalyzed reaction using 2′-deoxyGTP and 2′-chloroGTP as substrate analogues. AP Mehta, SH Abdelwahed, H Xu, TP Begley Journal of the American Chemical Society 136 (30), 10609-10614, 2014 | 28 | 2014 |
High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana S Coquille, C Roux, A Mehta, TP Begley, TB Fitzpatrick, S Thore Journal of structural biology 184 (3), 438-444, 2013 | 24 | 2013 |
Replacement of 2′-Deoxycytidine by 2′-Deoxycytidine Analogues in the E. coli Genome AP Mehta, H Li, SA Reed, L Supekova, T Javahishvili, PG Schultz Journal of the American Chemical Society 138 (43), 14230-14233, 2016 | 22 | 2016 |
Replacement of Thymidine by a Modified Base in the Escherichia coli Genome AP Mehta, H Li, SA Reed, L Supekova, T Javahishvili, PG Schultz Journal of the American Chemical Society 138 (23), 7272-7275, 2016 | 20 | 2016 |
Identification of the first riboflavin catabolic gene cluster isolated from Microbacterium maritypicum G10 H Xu, Y Chakrabarty, B Philmus, AP Mehta, D Bhandari, HP Hohmann, ... Journal of Biological Chemistry 291 (45), 23506-23515, 2016 | 18 | 2016 |
Engineering artificial photosynthetic life-forms through endosymbiosis JE Cournoyer, SD Altman, Y Gao, CL Wallace, D Zhang, GH Lo, ... Nature communications 13 (1), 2254, 2022 | 16 | 2022 |
An aminoimidazole radical intermediate in the anaerobic biosynthesis of the 5, 6-dimethylbenzimidazole ligand to vitamin B12 DM Gagnon, TA Stich, AP Mehta, SH Abdelwahed, TP Begley, RD Britt Journal of the American Chemical Society 140 (40), 12798-12807, 2018 | 12 | 2018 |
Toward a synthetic yeast endosymbiont with a minimal genome AP Mehta, Y Ko, L Supekova, K Pestonjamasp, J Li, PG Schultz Journal of the American Chemical Society 141 (35), 13799-13802, 2019 | 10 | 2019 |
Bacterial genome containing chimeric DNA–RNA sequences AP Mehta, Y Wang, SA Reed, L Supekova, T Javahishvili, JC Chaput, ... Journal of the American Chemical Society 140 (36), 11464-11473, 2018 | 9 | 2018 |
Molybdopterin biosynthesis—Mechanistic studies on a novel MoaA catalyzed insertion of a purine carbon into the ribose of GTP AP Mehta, SH Abdelwahed, TP Begley Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (9), 1073-1077, 2015 | 7 | 2015 |
Synthetic Platforms for Characterizing and Targeting of SARS-CoV-2 Genome Capping Enzymes MY Ornelas, AY Thomas, LI Johnson Rosas, RO Scoville, AP Mehta ACS synthetic biology 11 (11), 3759-3771, 2022 | 3 | 2022 |