| RNA binding antagonizes neurotoxic phase transitions of TDP-43 JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ... Neuron 102 (2), 321-338. e8, 2019 | 389 | 2019 |
| WNK kinases sense molecular crowding and rescue cell volume via phase separation CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ... Cell 185 (24), 4488-4506. e20, 2022 | 66 | 2022 |
| RNA modulates physiological and neuropathological protein phase transitions JR Mann, CJ Donnelly Neuron 109 (17), 2663-2681, 2021 | 40 | 2021 |
| Hypoxic-preconditioned bone marrow stem cell medium significantly improves outcome after retinal ischemia in rats S Roth, JC Dreixler, B Mathew, I Balyasnikova, JR Mann, V Boddapati, ... Investigative ophthalmology & visual science 57 (7), 3522-3532, 2016 | 30 | 2016 |
| NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility AM Gleixner, BM Verdone, CG Otte, EN Anderson, N Ramesh, ... Nature communications 13 (1), 3380, 2022 | 27 | 2022 |
| RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3 N Ramesh, EL Daley, AM Gleixner, JR Mann, S Kour, D Mawrie, ... Acta Neuropathologica Communications 8, 1-20, 2020 | 21 | 2020 |
| Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo CG Otte, TR Fortuna, JR Mann, AM Gleixner, N Ramesh, NJ Pyles, ... Neurobiology of disease 146, 105078, 2020 | 11 | 2020 |
| Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import JR Mann, ED McKenna, D Mawrie, V Papakis, F Alessandrini, ... Science Advances 9 (33), eadi5548, 2023 | 4 | 2023 |
| Nucleic acids and nucleic acid analogs for treating, preventing, and disrupting pathological polynucleotide-binding protein inclusions C Donnelly, J Mann, J Shorter, L Guo, B Portz US Patent App. 17/268,654, 2021 | 2 | 2021 |
| Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains L Guo, JR Mann, JC Mauna, KE Copley, H Wang, JD Rubien, HM Odeh, ... bioRxiv, 2023.09. 04.555754, 2023 | 1 | 2023 |
| Nup62 is recruited to pathological condensates and promotes TDP-43 insolubility in C9orf72 and sporadic ALS/FTLD. A Gleixner, BM Verdone, C Otte, N Ramesh, J Gale, J Mauna, J Mann, ... | 1 | 2021 |
| The role of RNA in antagonizing aberrant phase transitions of RNA-binding proteins in ALS/FTD JR Mann University of Pittsburgh, 2020 | 1 | 2020 |
| Optogenetic induction of neurodegenerative disease pathologies CJ Donnelly US Patent 11,945,847, 2024 | | 2024 |
| Optogenetic Induction of TDP-43 Proteinopathy In Vivo (S32. 005) C Otte, J Mann, U Pandey, C Donnelly Neurology 92 (15 Supplement), 2019 | | 2019 |
| Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats (vol 57, pg 3522, 2016) S Roth, JC Dreixler, B Mathew, I Balyasnikova, JR Mann, V Boddapati, ... INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 57 (8), 3926-3926, 2016 | | 2016 |
| Hypoxic Preconditioned Stem Cells and Rescue of Retinal Ischemia S Roth, J Dreixler, J Mann, I Balyasnikova Investigative Ophthalmology & Visual Science 56 (7), 28-28, 2015 | | 2015 |
| Delayed Rescue After Retinal Ischemia by Conditioned Media From Hypoxic Preconditioned Stem Cells S Roth, JC Dreixler, J Mann, I Balyasnikova, M Lesniak | | |
