| FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases R Furumai, A Matsuyama, N Kobashi, KH Lee, M Nishiyama, H Nakajima, ... Cancer research 62 (17), 4916-4921, 2002 | 1029 | 2002 |
| In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation A Matsuyama, T Shimazu, Y Sumida, A Saito, Y Yoshimatsu, ... The EMBO journal, 2002 | 850 | 2002 |
| Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin R Furumai, Y Komatsu, N Nishino, S Khochbin, M Yoshida, S Horinouchi Proceedings of the National Academy of Sciences 98 (1), 87-92, 2001 | 592 | 2001 |
| Protein lysine methyltransferase G9a acts on non-histone targets P Rathert, A Dhayalan, M Murakami, X Zhang, R Tamas, R Jurkowska, ... Nature chemical biology 4 (6), 344-346, 2008 | 400 | 2008 |
| Histone deacetylase as a new target for cancer chemotherapy M Yoshida, R Furumai, M Nishiyama, Y Komatsu, N Nishino, S Horinouchi Cancer chemotherapy and pharmacology 48, S20-S26, 2001 | 326 | 2001 |
| Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity Y Komatsu, K Tomizaki, M Tsukamoto, T Kato, N Nishino, S Sato, ... Cancer Research 61 (11), 4459-4466, 2001 | 230 | 2001 |
| From discovery to the coming generation of histone deacetylase inhibitors M Yoshida, A Matsuyama, Y Komatsu, N Nishino Current medicinal chemistry 10 (22), 2351-2358, 2003 | 166 | 2003 |
| Global analysis of gel mobility of proteins and its use in target identification A Shirai, A Matsuyama, Y Yashiroda, A Hashimoto, Y Kawamura, R Arai, ... Journal of Biological Chemistry 283 (16), 10745-10752, 2008 | 157 | 2008 |
| HIV‐1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses E Col, C Caron, C Chable‐Bessia, G Legube, S Gazzeri, Y Komatsu, ... The EMBO journal 24 (14), 2634-2645, 2005 | 119 | 2005 |
| Proteomic analysis of organ‐specific post‐translational lysine‐acetylation and‐methylation in mice by use of anti‐acetyllysine and‐methyllysine mouse monoclonal antibodies H Iwabata, M Yoshida, Y Komatsu Proteomics 5 (18), 4653-4664, 2005 | 116 | 2005 |
| Cyclic tetrapeptides bearing a sulfhydryl group potently inhibit histone deacetylases N Nishino, B Jose, S Okamura, S Ebisusaki, T Kato, Y Sumida, M Yoshida Organic letters 5 (26), 5079-5082, 2003 | 103 | 2003 |
| Regulation of E2A activities by histone acetyltransferases in B lymphocyte development C Bradney, M Hjelmeland, Y Komatsu, M Yoshida, TP Yao, Y Zhuang Journal of Biological Chemistry 278 (4), 2370-2376, 2003 | 100 | 2003 |
| Chlamydocin–hydroxamic acid analogues as histone deacetylase inhibitors N Nishino, B Jose, R Shinta, T Kato, Y Komatsu, M Yoshida Bioorganic & medicinal chemistry 12 (22), 5777-5784, 2004 | 59 | 2004 |
| A highly acid‐resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin … Y Aiba, Y Nakano, Y Koga, K Takahashi, Y Komatsu Microbiologyopen 4 (3), 465-474, 2015 | 58 | 2015 |
| Regulation of SV40 large T-antigen stability by reversible acetylation T Shimazu, Y Komatsu, KI Nakayama, H Fukazawa, S Horinouchi, ... Oncogene 25 (56), 7391-7400, 2006 | 55 | 2006 |
| Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand N Nishino, D Yoshikawa, LA Watanabe, T Kato, B Jose, Y Komatsu, ... Bioorganic & medicinal chemistry letters 14 (10), 2427-2431, 2004 | 51 | 2004 |
| Anti-Helicobacter pylori activity of non-living, heat-killed form of lactobacilli including Lactobacillus johnsonii No.1088 Y Aiba, H Ishikawa, M Tokunaga, Y Komatsu FEMS microbiology letters 364 (11), fnx102, 2017 | 46 | 2017 |
| CX-397, a novel recombinant hirudin analog having a hybrid sequence of hirudin variants-1 and-3 Y Komatsu, S Misawa, A Sukesada, Y Ohba, H Hayashi Biochemical and biophysical research communications 196 (2), 773-779, 1993 | 30 | 1993 |
| Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells Y Komatsu, H Hayashi The Journal of Antibiotics 51 (1), 89-91, 1998 | 29 | 1998 |
| Proteomic biomarkers for acute interstitial lung disease in gefitinib-treated Japanese lung cancer patients F Nyberg, A Ogiwara, CG Harbron, T Kawakami, K Nagasaka, S Takami, ... Plos one 6 (7), e22062, 2011 | 24 | 2011 |
