| Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1, 4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4, 5 … A Burguete, E Pontiki, D Hadjipavlou-Litina, R Villar, E Vicente, B Solano, ... Bioorganic & medicinal chemistry letters 17 (23), 6439-6443, 2007 | 251 | 2007 |
| Selective activity against Mycobacterium tuberculosis of new quinoxaline 1, 4-di-N-oxides E Vicente, S Pérez-Silanes, LM Lima, S Ancizu, A Burguete, B Solano, ... Bioorganic & medicinal chemistry 17 (1), 385-389, 2009 | 152 | 2009 |
| Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates NC Romeiro, G Aguirre, P Hernández, M González, H Cerecetto, I Aldana, ... Bioorganic & medicinal chemistry 17 (2), 641-652, 2009 | 149 | 2009 |
| New 1, 4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterium tuberculosis agents E Torres, E Moreno, S Ancizu, C Barea, S Galiano, I Aldana, A Monge, ... Bioorganic & medicinal chemistry letters 21 (12), 3699-3703, 2011 | 114 | 2011 |
| Novel Benzo[b]thiophene Derivatives as New Potential Antidepressants with Rapid Onset of Action L Berrade, B Aisa, MJ Ramirez, S Galiano, S Guccione, LR Moltzau, ... Journal of medicinal chemistry 54 (8), 3086-3090, 2011 | 109 | 2011 |
| Synthesis and structure–activity relationship of 3-phenylquinoxaline 1, 4-di-N-oxide derivatives as antimalarial agents E Vicente, LM Lima, E Bongard, S Charnaud, R Villar, B Solano, ... European journal of medicinal chemistry 43 (9), 1903-1910, 2008 | 103 | 2008 |
| New 3-methylquinoxaline-2-carboxamide 1, 4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents S Ancizu, E Moreno, B Solano, R Villar, A Burguete, E Torres, ... Bioorganic & medicinal chemistry 18 (7), 2713-2719, 2010 | 101 | 2010 |
| Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1, 4-di-N-oxide derivatives E Moreno, S Ancizu, S Pérez-Silanes, E Torres, I Aldana, A Monge European journal of medicinal chemistry 45 (10), 4418-4426, 2010 | 95 | 2010 |
| In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide R Villar, E Vicente, B Solano, S Pérez-Silanes, I Aldana, JA Maddry, ... Journal of Antimicrobial Chemotherapy 62 (3), 547-554, 2008 | 86 | 2008 |
| New 1-Aryl-3-(4-arylpiperazin-1-yl)propane Derivatives, with Dual Action at 5-HT1A Serotonin Receptors and Serotonin Transporter, as a New Class of … J Martínez-Esparza, AM Oficialdegui, S Pérez-Silanes, B Heras, L Orús, ... Journal of medicinal chemistry 44 (3), 418-428, 2001 | 85 | 2001 |
| 3-Trifluoromethylquinoxaline N,N′-Dioxides as Anti-Trypanosomatid Agents. Identification of Optimal Anti-T. cruzi Agents and Mechanism of Action Studies D Benitez, M Cabrera, P Hernández, L Boiani, ML Lavaggi, R Di Maio, ... Journal of medicinal chemistry 54 (10), 3624-3636, 2011 | 83 | 2011 |
| New salicylamide and sulfonamide derivatives of quinoxaline 1, 4-di-N-oxide with antileishmanial and antimalarial activities C Barea, A Pabón, D Castillo, M Zimic, M Quiliano, S Galiano, ... Bioorganic & medicinal chemistry letters 21 (15), 4498-4502, 2011 | 81 | 2011 |
| Synthesis and Biological Evaluation of New 2-Arylcarbonyl-3-trifluoromethylquinoxaline 1,4-Di-N-oxide Derivatives and Their Reduced Analogues B Solano, V Junnotula, A Marín, R Villar, A Burguete, E Vicente, ... Journal of medicinal chemistry 50 (22), 5485-5492, 2007 | 79 | 2007 |
| Heterocyclic-2-carboxylic Acid (3-Cyano-1,4-di-N-oxidequinoxalin-2-yl)amide Derivatives as Hits for the Development of Neglected Disease Drugs S Ancizu, E Moreno, E Torres, A Burguete, S Pérez-Silanes, D Benítez, ... Molecules 14 (6), 2256-2272, 2009 | 72 | 2009 |
| Efficacy of Quinoxaline-2-Carboxylate 1,4-Di-N-Oxide Derivatives in Experimental Tuberculosis E Vicente, R Villar, A Burguete, B Solano, S Pérez-Silanes, I Aldana, ... Antimicrobial agents and chemotherapy 52 (9), 3321-3326, 2008 | 72 | 2008 |
| Novel quinoxaline 1, 4-di-N-oxide derivatives as new potential antichagasic agents E Torres, E Moreno-Viguri, S Galiano, G Devarapally, PW Crawford, ... European journal of medicinal chemistry 66, 324-334, 2013 | 71 | 2013 |
| The role of imidazole and benzimidazole heterocycles in Chagas disease: A review I Beltran-Hortelano, V Alcolea, M Font, S Pérez-Silanes European journal of medicinal chemistry 206, 112692, 2020 | 70 | 2020 |
| Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT1A receptors L Orús, S Pérez-Silanes, AM Oficialdegui, J Martínez-Esparza, ... Journal of medicinal chemistry 45 (19), 4128-4139, 2002 | 70 | 2002 |
| Challenges in Chagas disease drug discovery: a review R Paucar, E Moreno-Viguri, S Pérez-Silanes Current Medicinal Chemistry 23 (28), 3154-3170, 2016 | 66 | 2016 |
| Design, synthesis, and characterization of N-oxide-containing heterocycles with in vivo sterilizing antitubercular activity GF dos Santos Fernandes, PC De Souza, E Moreno-Viguri, ... Journal of Medicinal Chemistry 60 (20), 8647-8660, 2017 | 62 | 2017 |
