Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2 MJ Schmeisser, E Ey, S Wegener, J Bockmann, AV Stempel, A Kuebler, ... Nature 486 (7402), 256-260, 2012 | 678 | 2012 |
Environmental factors in autism AM Grabrucker Frontiers in psychiatry 3, 36698, 2013 | 309 | 2013 |
Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation AM Grabrucker, MJ Knight, C Proepper, J Bockmann, M Joubert, ... The EMBO journal 30 (3), 569-581, 2011 | 262 | 2011 |
Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies AM Grabrucker, MJ Schmeisser, M Schoen, TM Boeckers Trends in cell biology 21 (10), 594-603, 2011 | 250 | 2011 |
Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin–neuroligin-mediated transsynaptic signaling MH Arons, CJ Thynne, AM Grabrucker, D Li, M Schoen, JE Cheyne, ... Journal of Neuroscience 32 (43), 14966-14978, 2012 | 205 | 2012 |
Nanoparticle transport across the blood brain barrier AM Grabrucker, B Ruozi, D Belletti, F Pederzoli, F Forni, MA Vandelli, ... Tissue barriers 4 (1), e1153568, 2016 | 186 | 2016 |
Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders S Grabrucker, L Jannetti, M Eckert, S Gaub, R Chhabra, S Pfaender, ... Brain 137 (1), 137-152, 2014 | 185 | 2014 |
Novel Curcumin loaded nanoparticles engineered for Blood-Brain Barrier crossing and able to disrupt Abeta aggregates R Barbara, D Belletti, F Pederzoli, M Masoni, J Keller, A Ballestrazzi, ... International journal of pharmaceutics 526 (1-2), 413-424, 2017 | 156 | 2017 |
Small-molecule XIAP inhibitors enhance γ-irradiation-induced apoptosis in glioblastoma SHK Vellanki, A Grabrucker, S Liebau, C Proepper, A Eramo, V Braun, ... Neoplasia 11 (8), 743-W9, 2009 | 148 | 2009 |
De novo mutations in protein kinase genes CAMK2A and CAMK2B cause intellectual disability S Küry, GM van Woerden, T Besnard, MP Onori, X Latypova, MC Towne, ... The American Journal of Human Genetics 101 (5), 768-788, 2017 | 145 | 2017 |
Synaptogenesis of hippocampal neurons in primary cell culture A Grabrucker, B Vaida, J Bockmann, TM Boeckers Cell and tissue research 338 (3), 333-341, 2009 | 144 | 2009 |
Characterization of biometal profiles in neurological disorders S Pfaender, AM Grabrucker Metallomics 6 (5), 960-977, 2014 | 119 | 2014 |
Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers JJE Mulvihill, EM Cunnane, AM Ross, JT Duskey, G Tosi, AM Grabrucker Nanomedicine 15 (2), 205-214, 2020 | 115 | 2020 |
Behavioral impairments in animal models for zinc deficiency S Hagmeyer, JC Haderspeck, AM Grabrucker Frontiers in behavioral neuroscience 8, 443, 2015 | 114 | 2015 |
Brain-delivery of zinc-ions as potential treatment for neurological diseases: mini review A M Grabrucker, M Rowan, C C Garner Drug delivery letters 1 (1), 13-23, 2011 | 109 | 2011 |
A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders AM Grabrucker Developmental neurobiology 74 (2), 136-146, 2014 | 107 | 2014 |
Zinc in gut-brain interaction in autism and neurological disorders G Vela, P Stark, M Socha, AK Sauer, S Hagmeyer, AM Grabrucker Neural plasticity 2015, 2015 | 106 | 2015 |
Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution A Vilella, G Tosi, AM Grabrucker, B Ruozi, D Belletti, MA Vandelli, ... Journal of controlled release 174, 195-201, 2014 | 106 | 2014 |
Autism spectrum disorders: etiology and pathology AK Sauer, J Stanton, S Hans, A Grabrucker Exon Publications, 1-15, 2021 | 85 | 2021 |
Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC AK Sauer, S Pfaender, S Hagmeyer, L Tarana, AK Mattes, F Briel, S Küry, ... Biometals 30, 643-661, 2017 | 80 | 2017 |