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Zachary J. Reitman, MD, PhD
Zachary J. Reitman, MD, PhD
Verified email at duke.edu - Homepage
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Cited by
Year
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
PJ Killela, ZJ Reitman, Y Jiao, C Bettegowda, N Agrawal, LA Diaz Jr, ...
Proceedings of the National Academy of Sciences 110 (15), 6021-6026, 2013
15262013
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
Y Jiao, PJ Killela, ZJ Reitman, BA Rasheed, CM Heaphy, RF De Wilde, ...
Oncotarget 3 (7), 709, 2012
6832012
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism
ZJ Reitman, H Yan
Journal of the National Cancer Institute 102 (13), 932-941, 2010
6192010
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
ZJ Reitman, G Jin, ED Karoly, I Spasojevic, J Yang, KW Kinzler, Y He, ...
Proceedings of the National Academy of Sciences 108 (8), 3270-3275, 2011
4812011
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas
PJ Killela, CJ Pirozzi, P Healy, ZJ Reitman, E Lipp, BA Rasheed, R Yang, ...
Oncotarget 5 (6), 1515, 2014
2932014
Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas
L Zhang, LH Chen, H Wan, R Yang, Z Wang, J Feng, S Yang, S Jones, ...
Nature genetics 46 (7), 726-730, 2014
1812014
Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas
G Jin, ZJ Reitman, CG Duncan, I Spasojevic, DM Gooden, BA Rasheed, ...
Cancer research 73 (2), 496-501, 2013
1532013
2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP+-dependent isocitrate dehydrogenase mutations
G Jin, ZJ Reitman, I Spasojevic, I Batinic-Haberle, J Yang, ...
PloS one 6 (2), e16812, 2011
1382011
The genome-wide mutational landscape of pituitary adenomas
ZJ Song, ZJ Reitman, ZY Ma, JH Chen, QL Zhang, XF Shou, CX Huang, ...
Cell research 26 (11), 1255-1259, 2016
1372016
Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia
ZJ Reitman, CG Duncan, E Poteet, A Winters, LJ Yan, DM Gooden, ...
Journal of Biological Chemistry 289 (34), 23318-23328, 2014
1012014
IDH1 and IDH2: not your typical oncogenes
ZJ Reitman, DW Parsons, H Yan
Cancer cell 17 (3), 215-216, 2010
902010
The genetic landscape of anaplastic astrocytoma
PJ Killela, CJ Pirozzi, ZJ Reitman, S Jones, BA Rasheed, E Lipp, ...
Oncotarget 5 (6), 1452, 2014
812014
Exomic sequencing of four rare central nervous system tumor types
C Bettegowda, N Agrawal, Y Jiao, Y Wang, LD Wood, FJ Rodriguez, ...
Oncotarget 4 (4), 572, 2013
802013
IDH1R132 mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain
GY Lopez, ZJ Reitman, D Solomon, T Waldman, DD Bigner, ...
Biochemical and biophysical research communications 398 (3), 585-587, 2010
782010
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
ZJ Reitman, BR Paolella, G Bergthold, K Pelton, S Becker, R Jones, ...
Nature communications 10 (1), 3731, 2019
552019
Picornavirus genome replication: identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a …
M Shen, ZJ Reitman, Y Zhao, I Moustafa, Q Wang, JJ Arnold, HB Pathak, ...
Journal of biological chemistry 283 (2), 875-888, 2008
502008
New directions in the treatment of glioblastoma
ZJ Reitman, F Winkler, AEH Elia
Seminars in neurology 38 (01), 050-061, 2018
432018
IDH1 and IDH2 hotspot mutations are not found in canine glioma
ZJ Reitman, NJ Olby, CL Mariani, R Thomas, M Breen, DD Bigner, ...
International journal of cancer. Journal international du cancer 127 (1), 245, 2010
372010
Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila
ZJ Reitman, SA Sinenko, EP Spana, H Yan
Blood, The Journal of the American Society of Hematology 125 (2), 336-345, 2015
332015
Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition
JT Low, V Chandramohan, ML Bowie, MC Brown, MS Waitkus, A Briley, ...
Cancer Cell 40 (5), 439-440, 2022
292022
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