Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine B van Loon, E Markkanen, U Hübscher DNA repair 9 (6), 604-616, 2010 | 365 | 2010 |
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ... Cell metabolism 19 (6), 1034-1041, 2014 | 277 | 2014 |
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ B van Loon, U Hübscher Proceedings of the National Academy of Sciences 106 (43), 18201-18206, 2009 | 130 | 2009 |
HUWE1 variants cause dominant X-linked intellectual disability: a clinical study of 21 patients S Moortgat, S Berland, I Aukrust, I Maystadt, L Baker, V Benoit, ... European Journal of Human Genetics 26 (1), 64-74, 2018 | 93 | 2018 |
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination E Markkanen, B van Loon, E Ferrari, JL Parsons, GL Dianov, U Hübscher Proceedings of the National Academy of Sciences 109 (2), 437-442, 2012 | 86 | 2012 |
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair G Maga, E Crespan, U Wimmer, B van Loon, A Amoroso, C Mondello, ... Proceedings of the National Academy of Sciences 105 (52), 20689-20694, 2008 | 80 | 2008 |
HUWE1 mutations in Juberg-Marsidi and Brooks syndromes: the results of an X-chromosome exome sequencing study MJ Friez, SS Brooks, RE Stevenson, M Field, MJ Basehore, LC Adès, ... BMJ open 6 (4), e009537, 2016 | 61 | 2016 |
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7, 8-dihydroguanine bypass G Maga, E Crespan, E Markkanen, R Imhof, A Furrer, G Villani, ... Proceedings of the National Academy of Sciences 110 (47), 18850-18855, 2013 | 56 | 2013 |
Regulation of oxidative DNA damage repair: the adenine: 8-oxo-guanine problem E Markkanen, U Hübscher, B van Loon Cell Cycle 11 (6), 1070-1075, 2012 | 48 | 2012 |
Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair E Crespan, A Furrer, M Rösinger, F Bertoletti, E Mentegari, G Chiapparini, ... Nature communications 7 (1), 10805, 2016 | 45 | 2016 |
Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB) B Van Loon, LD Samson DNA repair 12 (3), 177-187, 2013 | 43 | 2013 |
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ N Selak, CZ Bachrati, I Shevelev, T Dietschy, B Loon, A Jacob, ... Nucleic acids research 36 (16), 5166-5179, 2008 | 43 | 2008 |
Base excision repair in physiology and pathology of the central nervous system M Bosshard, E Markkanen, B Van Loon International journal of molecular sciences 13 (12), 16172-16222, 2012 | 40 | 2012 |
Base excision repair in physiology and pathology of the central nervous system M Bosshard, E Markkanen, B Van Loon International journal of molecular sciences 13 (12), 16172-16222, 2012 | 40 | 2012 |
Genotype–phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies V Simonelli, S Camerini, F Mazzei, B Van Loon, A Allione, M D'Errico, ... Free Radical Biology and Medicine 63, 401-409, 2013 | 37 | 2013 |
Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint E Zucca, F Bertoletti, U Wimmer, E Ferrari, G Mazzini, S Khoronenkova, ... Nucleic acids research 41 (1), 229-241, 2013 | 36 | 2013 |
Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity E Mentegari, E Crespan, L Bavagnoli, M Kissova, F Bertoletti, ... Nucleic acids research 45 (5), 2600-2614, 2017 | 35 | 2017 |
Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions A Martín-Pardillos, A Tsaalbi-Shtylik, S Chen, S Lazare, RP Os, ... Blood, The Journal of the American Society of Hematology 130 (13), 1523-1534, 2017 | 33 | 2017 |
The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants D Fu, LD Samson, U Hübscher, B van Loon DNA repair 35, 13-18, 2015 | 33 | 2015 |
The block of DNA polymerase δ strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase β and flap endonuclease 1 G Maga, B van Loon, E Crespan, G Villani, U Hubscher Journal of biological chemistry 284 (21), 14267-14275, 2009 | 33 | 2009 |