| Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised … B Burtness, KJ Harrington, R Greil, D Soulières, M Tahara, G de Castro, ... The Lancet 394 (10212), 1915-1928, 2019 | 2272 | 2019 |
| Efficacy and safety of pembrolizumab or pembrolizumab plus chemotherapy vs chemotherapy alone for patients with first-line, advanced gastric cancer: the KEYNOTE-062 phase 3 … K Shitara, E Van Cutsem, YJ Bang, C Fuchs, L Wyrwicz, KW Lee, ... JAMA oncology 6 (10), 1571-1580, 2020 | 791 | 2020 |
| Diffuse noxious inhibitory controls (DNIC) in animals and in man. D Le Bars, L Villanueva, D Bouhassira, JC Willer Patologicheskaia fiziologiia i eksperimental'naia terapiia, 55-65, 1992 | 400 | 1992 |
| The activation of bulbo-spinal controls by peripheral nociceptive inputs: diffuse noxious inhibitory controls L Villanueva, D Le Bars Biological research 28, 113-113, 1995 | 304 | 1995 |
| Involvement of the subnucleus reticularis dorsalis in diffuse noxious inhibitory controls in the rat D Bouhassira, L Villanueva, Z Bing, D le Bars Brain research 595 (2), 353-357, 1992 | 233 | 1992 |
| Organization of the efferent projections from the spinal cervical enlargement to the parabrachial area and periaqueductal graye. A PHA‐L study in the rat JF Bernard, R Dallel, P Raboisson, L Villanueva, DL Bars Journal of Comparative Neurology 353 (4), 480-505, 1995 | 224 | 1995 |
| Acupuncture and diffuse noxious inhibitory controls: naloxone-reversible depression of activities of trigeminal convergent neurons Z Bing, L Villanueva, D Le Bars Neuroscience 37 (3), 809-818, 1990 | 208 | 1990 |
| The medullary subnucleus reticularis dorsalis (SRD) as a key link in both the transmission and modulation of pain signals L Villanueva, D Bouhassira, D Le Bars Pain 67 (2), 231-240, 1996 | 198 | 1996 |
| Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches C Robert, L Bourgeais, CD Arreto, M Condes-Lara, R Noseda, T Jay, ... Journal of Neuroscience 33 (20), 8827-8840, 2013 | 163 | 2013 |
| Convergence of heterotopic nociceptive information onto subnucleus reticularis dorsalis neurons in the rat medulla L Villanueva, D Bouhassira, Z Bing, D Le Bars Journal of neurophysiology 60 (3), 980-1009, 1988 | 160 | 1988 |
| Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised … T Powles, P Tomczak, SH Park, B Venugopal, T Ferguson, ... The lancet oncology 23 (9), 1133-1144, 2022 | 155 | 2022 |
| Depression of activities of dorsal horn convergent neurones by propriospinal mechanisms triggered by noxious inputs; comparison with diffuse noxious inhibitory controls (DNIC) SW Cadden, L Villanueva, D Chitour, D Le Bars Brain research 275 (1), 1-11, 1983 | 149 | 1983 |
| Differential projections to the intralaminar and gustatory thalamus from the parabrachial area: a PHA‐L study in the rat H Bester, L Bourgeais, L Villanueva, JM Besson, JF Bernard Journal of Comparative Neurology 405 (4), 421-449, 1999 | 140 | 1999 |
| Electrophysiological evidence for the activation of descending inhibitory controls by nociceptive afferent pathways D Le Bars, L Villanueva Progress in brain research 77, 275-299, 1988 | 123 | 1988 |
| Changes of meningeal excitability mediated by corticotrigeminal networks: a link for the endogenous modulation of migraine pain R Noseda, L Constandil, L Bourgeais, M Chalus, L Villanueva Journal of Neuroscience 30 (43), 14420-14429, 2010 | 122 | 2010 |
| Involvement of the dorsolateral funiculus in the descending spinal projections responsible for diffuse noxious inhibitory controls in the rat L Villanueva, D Chitour, D Le Bars Journal of neurophysiology 56 (4), 1185-1195, 1986 | 108 | 1986 |
| Aspects of sensory processing through convergent neurons D Le Bars, AH Dickenson, JM Besson, L Villanueva Spinal afferent processing, 467-504, 1986 | 106 | 1986 |
| Encoding of electrical, thermal, and mechanical noxious stimuli by subnucleus reticularis dorsalis neurons in the rat medulla L Villanueva, Z Bing, D Bouhassira, D Le Bars Journal of Neurophysiology 61 (2), 391-402, 1989 | 101 | 1989 |
| Ascending pathways in the spinal cord involved in triggering of diffuse noxious inhibitory controls in the rat L Villanueva, M Peschanski, B Calvino, D Le Bars Journal of neurophysiology 55 (1), 34-55, 1986 | 101 | 1986 |
| Dorsal horn (convergent) neurones in the intact anaesthetized arthritic rat. I. Segmental excitatory influences B Calvino, L Villanueva, D Le Bars Pain 28 (1), 81-98, 1987 | 100 | 1987 |
