| Lysosomal metabolomics reveals V-ATPase-and mTOR-dependent regulation of amino acid efflux from lysosomes M Abu-Remaileh, GA Wyant, C Kim, NN Laqtom, M Abbasi, SH Chan, ... Science 358 (6364), 807-813, 2017 | 519 | 2017 |
| A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ... Nature chemical biology 12 (6), 452-458, 2016 | 471 | 2016 |
| Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability MR Sullivan, LV Danai, CA Lewis, SH Chan, DY Gui, T Kunchok, ... Elife 8, e44235, 2019 | 406 | 2019 |
| NUFIP1 is a ribosome receptor for starvation-induced ribophagy GA Wyant, M Abu-Remaileh, EM Frenkel, NN Laqtom, V Dharamdasani, ... Science 360 (6390), 751-758, 2018 | 319 | 2018 |
| Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ... Nature 567 (7746), 118-122, 2019 | 304 | 2019 |
| Histidine catabolism is a major determinant of methotrexate sensitivity N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ... Nature 559 (7715), 632-636, 2018 | 275 | 2018 |
| Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila SH Chan, AM Yu, M McVey PLoS genetics 6 (7), e1001005, 2010 | 274 | 2010 |
| SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism N Kory, GA Wyant, G Prakash, J uit de Bos, F Bottanelli, ME Pacold, ... Science 362 (6416), eaat9528, 2018 | 162 | 2018 |
| Dihydroxyacetone phosphate signals glucose availability to mTORC1 JM Orozco, PA Krawczyk, SM Scaria, AL Cangelosi, SH Chan, T Kunchok, ... Nature metabolism 2 (9), 893-901, 2020 | 161 | 2020 |
| MCART1/SLC25A51 is required for mitochondrial NAD transport N Kory, J uit de Bos, S van der Rijt, N Jankovic, M Güra, N Arp, IA Pena, ... Science advances 6 (43), eabe5310, 2020 | 113 | 2020 |
| MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ... Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019 | 89 | 2019 |
| MFSD12 mediates the import of cysteine into melanosomes and lysosomes CH Adelmann, AK Traunbauer, B Chen, KJ Condon, SH Chan, T Kunchok, ... Nature 588 (7839), 699-704, 2020 | 65 | 2020 |
| m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis GG Bushkin, D Pincus, JT Morgan, K Richardson, C Lewis, SH Chan, ... Nature communications 10 (1), 3414, 2019 | 58 | 2019 |
| Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ... Nature communications 10 (1), 5604, 2019 | 52 | 2019 |
| CLN3 is required for the clearance of glycerophosphodiesters from lysosomes NN Laqtom, W Dong, UN Medoh, AL Cangelosi, V Dharamdasani, ... Nature 609 (7929), 1005-1011, 2022 | 47 | 2022 |
| Coupling of protein condensates to ordered lipid domains determines functional membrane organization HY Wang, SH Chan, S Dey, I Castello-Serrano, MK Rosen, JA Ditlev, ... Science advances 9 (17), eadf6205, 2023 | 45 | 2023 |
| Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine AL Cangelosi, AM Puszynska, JM Roberts, A Armani, TP Nguyen, ... Science 377 (6601), 47-56, 2022 | 25 | 2022 |
| 6-Phosphogluconate dehydrogenase links cytosolic carbohydrate metabolism to protein secretion via modulation of glutathione levels H Li, M Ericsson, B Rabasha, B Budnik, SH Chan, E Freinkman, CA Lewis, ... Cell chemical biology 26 (9), 1306-1314. e5, 2019 | 25 | 2019 |
| Screening in serum-derived medium reveals differential response to compounds targeting metabolism KL Abbott, A Ali, D Casalena, BT Do, R Ferreira, JH Cheah, CK Soule, ... Cell chemical biology 30 (9), 1156-1168. e7, 2023 | 8 | 2023 |
| Rab3 mediates a pathway for endocytic sorting and plasma membrane recycling of ordered microdomains B Diaz-Rohrer, I Castello-Serrano, SH Chan, HY Wang, CR Shurer, ... Proceedings of the National Academy of Sciences 120 (10), e2207461120, 2023 | 8 | 2023 |
Caroline A. (Lewis) ChidleyUMass Chan Medical SchoolVerified email at umassmed.edu
