| The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation JH Chung, MC Ostrowski, T Romigh, T Minaguchi, KA Waite, C Eng Human molecular genetics 15 (17), 2553-2559, 2006 | 156 | 2006 |
| Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma M Orloff, C Peterson, X He, S Ganapathi, B Heald, Y Yang, G Bebek, ... JAmA 306 (4), 410-419, 2011 | 146 | 2011 |
| Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and-independent mechanisms in prostate cancer cell lines Y Wang, T Romigh, X He, MS Orloff, RH Silverman, WD Heston, C Eng Human molecular genetics 19 (22), 4319-4329, 2010 | 121 | 2010 |
| Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers Y Wang, T Romigh, X He, MH Tan, MS Orloff, RH Silverman, WD Heston, ... Oncogene 30 (42), 4327-4338, 2011 | 108 | 2011 |
| Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production AK Tilot, MK Gaugler, Q Yu, T Romigh, W Yu, RH Miller, TW Frazier, ... Human molecular genetics 23 (12), 3212-3227, 2014 | 76 | 2014 |
| Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function GP Lobo, KA Waite, SM Planchon, T Romigh, NT Nassif, C Eng Human molecular genetics 18 (15), 2851-2862, 2009 | 58 | 2009 |
| Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder AK Tilot, G Bebek, F Niazi, JB Altemus, T Romigh, TW Frazier, C Eng Molecular psychiatry 21 (1), 118-125, 2016 | 57 | 2016 |
| ATP modulates PTEN subcellular localization in multiple cancer cell lines GP Lobo, KA Waite, SM Planchon, T Romigh, JA Houghton, C Eng Human molecular genetics 17 (18), 2877-2885, 2008 | 51 | 2008 |
| Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53 X He, Y Ni, Y Wang, T Romigh, C Eng Human molecular genetics 20 (1), 80-89, 2011 | 44 | 2011 |
| Disruption of transforming growth factor-β signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis KL Bennett, T Romigh, C Eng Cancer research 69 (24), 9301-9305, 2009 | 37 | 2009 |
| Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome HJ Chen, T Romigh, K Sesock, C Eng Human mutation 38 (10), 1372-1377, 2017 | 34 | 2017 |
| Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation Y Wang, Q Yu, X He, T Romigh, J Altemus, C Eng Molecular Cancer Therapeutics 13 (2), 517-527, 2014 | 28 | 2014 |
| Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity X He, N Arrotta, D Radhakrishnan, Y Wang, T Romigh, C Eng Cancer research 73 (10), 3029-3040, 2013 | 28 | 2013 |
| Exome sequencing reveals germline SMAD9 mutation that reduces phosphatase and tensin homolog expression and is associated with hamartomatous polyposis and gastrointestinal … J Ngeow, W Yu, L Yehia, F Niazi, J Chen, X Tang, B Heald, J Lei, ... Gastroenterology 149 (4), 886-889. e5, 2015 | 26 | 2015 |
| PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome X He, M Saji, D Radhakrishnan, T Romigh, J Ngeow, Q Yu, Y Wang, ... The Journal of Clinical Endocrinology & Metabolism 97 (11), E2179-E2187, 2012 | 25 | 2012 |
| Nuclear PTEN levels and G2 progression in melanoma cells AI Jacob, T Romigh, KA Waite, C Eng Melanoma research 19 (4), 203-210, 2009 | 24 | 2009 |
| Utility of PTEN Protein Dosage in Predicting for Underlying Germline PTEN Mutations among Patients Presenting with Thyroid Cancer and Cowden-Like Phenotypes J Ngeow, X He, JL Mester, J Lei, T Romigh, MS Orloff, M Milas, C Eng The Journal of Clinical Endocrinology & Metabolism 97 (12), E2320-E2327, 2012 | 23 | 2012 |
| AP-2α Induces Epigenetic Silencing of Tumor Suppressive Genes and Microsatellite Instability in Head and Neck Squamous Cell Carcinoma KL Bennett, T Romigh, C Eng PLoS One 4 (9), e6931, 2009 | 23 | 2009 |
| Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits X He, S Thacker, T Romigh, Q Yu, TW Frazier, C Eng Molecular Autism 6, 1-10, 2015 | 22 | 2015 |
| Activator protein 2 alpha (AP2α) suppresses 42 kDa C/CAAT enhancer binding protein α (p42C/EBPα) in head and neck squamous cell carcinoma KL Bennett, T Romigh, K Arab, RE Teresi, Y Tada, C Eng, C Plass International journal of cancer 124 (6), 1285-1292, 2009 | 22 | 2009 |
