| H3K36 methylation antagonizes PRC2-mediated H3K27 methylation W Yuan, M Xu, C Huang, N Liu, S Chen, B Zhu Journal of Biological Chemistry 286 (10), 7983-7989, 2011 | 570 | 2011 |
| Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch N Liu, VV Hargreaves, Q Zhu, JV Kurland, J Hong, W Kim, F Sher, ... Cell 173 (2), 430-442. e17, 2018 | 387 | 2018 |
| Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation W Yuan, T Wu, H Fu, C Dai, H Wu, N Liu, X Li, M Xu, Z Zhang, T Niu, ... Science 337 (6097), 971-975, 2012 | 311 | 2012 |
| Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability N Liu, Z Zhang, H Wu, Y Jiang, L Meng, J Xiong, Z Zhao, X Zhou, J Li, H Li, ... Genes & development 29 (4), 379-393, 2015 | 121 | 2015 |
| CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis Q Zhu, N Liu, SH Orkin, GC Yuan Genome biology 20 (1), 1-12, 2019 | 116 | 2019 |
| Transcription factor competition at the γ-globin promoters controls hemoglobin switching N Liu, S Xu, Q Yao, Q Zhu, Y Kai, JY Hsu, P Sakon, L Pinello, GC Yuan, ... Nature genetics 53 (4), 511-520, 2021 | 66 | 2021 |
| Structural basis for substrate preference of SMYD3, a SET domain-containing protein lysine methyltransferase W Fu, N Liu, Q Qiao, M Wang, J Min, B Zhu, RM Xu, N Yang Journal of Biological Chemistry 291 (17), 9173-9180, 2016 | 36 | 2016 |
| SENP6-mediated M18BP1 deSUMOylation regulates CENP-A centromeric localization H Fu, N Liu, Q Dong, C Ma, J Yang, J Xiong, Z Zhang, X Qi, C Huang, ... Cell research 29 (3), 254-257, 2019 | 33 | 2019 |
| Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9 X Liu, Y Chen, Y Zhang, Y Liu, N Liu, GA Botten, H Cao, SH Orkin, ... Genome Biology 21 (1), 1-20, 2020 | 29 | 2020 |
| A unified model of human hemoglobin switching through single-cell genome editing Y Shen, JM Verboon, Y Zhang, N Liu, YJ Kim, S Marglous, ... Nature communications 12 (1), 4991, 2021 | 22 | 2021 |
| Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1 LS Ludwig, CA Lareau, EL Bao, N Liu, T Utsugisawa, AM Tseng, ... Blood, The Journal of the American Society of Hematology 139 (16), 2534-2546, 2022 | 20 | 2022 |
| Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis D Wang, M Tanaka-Yano, E Meader, MA Kinney, V Morris, EL da Rocha, ... Cell reports 39 (1), 2022 | 13 | 2022 |
| Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b SJ Patel, N Liu, S Piaker, A Gulko, ML Andrade, FD Heyward, ... Science translational medicine 14 (637), eabh3831, 2022 | 10 | 2022 |
| Droplet-based high-throughput single microbe RNA sequencing by smRandom-seq Z Xu, Y Wang, K Sheng, R Rosenthal, N Liu, X Hua, T Zhang, J Chen, ... Nature Communications 14 (1), 5130, 2023 | 6 | 2023 |
| CD38‐Specific CAR Integrated into CD38 Locus Driven by Different Promoters Causes Distinct Antitumor Activities of T and NK Cells C Liao, Y Wang, Y Huang, Y Duan, Y Liang, J Chen, J Jiang, K Shang, ... Advanced Science 10 (27), 2207394, 2023 | 5 | 2023 |
| Fetal hemoglobin (HbF) silencer BCL11A acts through a novel DNA-motif in the gamma-globin promoters, simplifying the model for hemoglobin switching N Liu, VV Hargreaves, J Hong, W Kim, J Kurland, Q Zhu, F Sher, ... Blood 130, 283, 2017 | 3 | 2017 |
| Integrated genomic analysis of AgRP neurons reveals that IRF3 regulates leptin’s hunger-suppressing effects FD Heyward, N Liu, C Jacobs, R Ivison, N Machado, A Uner, H Srinivasan, ... bioRxiv, 2022.01. 03.474708, 2022 | 2 | 2022 |
| High-efficiency HDR in immortalized cell lines by crude rAAV mediated donor template delivery S Mehta, A Buyanbat, G Zheng, N Liu, S Orkin BioRxiv, 2022.05. 02.490359, 2022 | 2 | 2022 |
| Identifying Quantitatively Differential Chromosomal Compartmentalization Changes and Their Biological Significance from Hi-C data using DARIC Y Kai, N Liu, SH Orkin, GC Yuan | 1 | 2023 |
| Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1 WW Sugden, Z LeBlanc, M Tanaka-Yano, R Jing, MG di Tillio, M Najia, ... Blood 142, 1309, 2023 | | 2023 |
Stuart OrkinVerified email at dfci.harvard.edu
