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Dave Gau
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SRF'ing and SAP'ing–the role of MRTF proteins in cell migration
D Gau, P Roy
Journal of cell science 131 (19), jcs218222, 2018
832018
Both actin and polyproline interactions of profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells
Z Ding, D Gau, B Deasy, A Wells, P Roy
Experimental cell research 315 (17), 2963-2973, 2009
752009
Green fluorescent protein expression triggers proteome changes in breast cancer cells
JVF Coumans, D Gau, A Poljak, V Wasinger, P Roy, P Moens
Experimental cell research 320 (1), 33-45, 2014
482014
Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by …
JVF Coumans, D Gau, A Poljak, V Wasinger, P Roy, PDJ Moens
Omics: a journal of integrative biology 18 (12), 778-791, 2014
402014
BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility–A proteomics study
DM Gau, JL Lesnock, BL Hood, R Bhargava, M Sun, K Darcy, S Luthra, ...
Cell Cycle 14 (12), 1884-1892, 2015
392015
Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis
D Gau, W Veon, TL Capasso, R Bottcher, S Shroff, BL Roman, P Roy
Angiogenesis 20, 663-672, 2017
342017
Actin-binding protein profilin1 promotes aggressiveness of clear-cell renal cell carcinoma cells
A Allen, D Gau, P Francoeur, J Sturm, Y Wang, R Martin, J Maranchie, ...
Journal of Biological Chemistry 295 (46), 15636-15649, 2020
242020
The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms
M Joy, D Gau, N Castellucci, R Prywes, P Roy
Journal of Biological Chemistry 292 (28), 11777-11791, 2017
242017
Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1–actin interaction
D Gau, T Lewis, L McDermott, P Wipf, D Koes, P Roy
Journal of Biological Chemistry 293 (7), 2606-2616, 2018
222018
Low PIP2 molar fractions induce nanometer size clustering in giant unilamellar vesicles
IL Salvemini, DM Gau, J Reid, LA Bagatolli, A Macmillan, PDJ Moens
Chemistry and physics of lipids 177, 51-63, 2014
192014
Threonine 89 is an important residue of profilin-1 that is phosphorylatable by protein kinase A
D Gau, W Veon, X Zeng, N Yates, SG Shroff, DR Koes, P Roy
PloS one 11 (5), e0156313, 2016
172016
Fluorescence Resonance Energy Transfer (FRET)-based Detection of Profilin–VASP Interaction
D Gau, Z Ding, C Baty, P Roy
Cellular and molecular bioengineering 4, 1-8, 2011
172011
Mitochondria–actin cytoskeleton crosstalk in cell migration
T Yadav, D Gau, P Roy
Journal of cellular physiology 237 (5), 2387-2403, 2022
162022
The VASP–profilin1 (Pfn1) interaction is critical for efficient cell migration and is regulated by cell–substrate adhesion in a PKA-dependent manner
D Gau, W Veon, SG Shroff, P Roy
Journal of Biological Chemistry 294 (17), 6972-6985, 2019
162019
Single cell migration assay using human breast cancer MDA-MB-231 cell line
DM Gau, P Roy
Bio-protocol 10 (8), e3586-e3586, 2020
142020
Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization
D Gau, L Vignaud, A Allen, Z Guo, J Sahel, D Boone, D Koes, ...
Journal of Biological Chemistry 295 (28), 9618-9629, 2020
132020
Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells
S Chakraborty, C Jiang, D Gau, M Oddo, Z Ding, L Vollmer, M Joy, ...
British journal of cancer 119 (9), 1106-1117, 2018
132018
The role of profilin-1 in cardiovascular diseases
A Allen, D Gau, P Roy
Journal of Cell Science 134 (9), jcs249060, 2021
102021
Myocardin‐related transcription factor's interaction with serum‐response factor is critical for outgrowth initiation, progression, and metastatic colonization of breast cancer …
D Gau, P Chawla, I Eder, P Roy
FASEB BioAdvances 4 (8), 509, 2022
42022
Inhibition of ocular neovascularization by novel anti-angiogenic compound
D Gau, L Vignaud, P Francoeur, D Koes, X Guillonneau, P Roy
Experimental eye research 213, 108861, 2021
42021
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