| Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation YC Wong, ELF Holzbaur Proceedings of the National Academy of Sciences 111 (42), E4439-E4448, 2014 | 786 | 2014 |
| Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 727 | 2017 |
| α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies YC Wong, D Krainc Nature medicine 23 (2), 1-13, 2017 | 681 | 2017 |
| Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis YC Wong, D Ysselstein, D Krainc Nature 554 (7692), 382-386, 2018 | 653 | 2018 |
| The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation YC Wong, ELF Holzbaur Journal of Neuroscience 34 (4), 1293-1305, 2014 | 396 | 2014 |
| Synaptic, mitochondrial, and lysosomal dysfunction in Parkinson’s disease M Nguyen, YC Wong, D Ysselstein, A Severino, D Krainc Trends in neurosciences 42 (2), 140-149, 2019 | 248 | 2019 |
| Regulation and function of mitochondria–lysosome membrane contact sites in cellular homeostasis YC Wong, S Kim, W Peng, D Krainc Trends in cell biology 29 (6), 500-513, 2019 | 218 | 2019 |
| Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission–fusion balance within mitochondrial networks AS Moore, YC Wong, CL Simpson, ELF Holzbaur Nature communications 7 (1), 12886, 2016 | 213 | 2016 |
| Mitochondria-lysosome contacts regulate mitochondrial Ca2+ dynamics via lysosomal TRPML1 W Peng, YC Wong, D Krainc Proceedings of the National Academy of Sciences 117 (32), 19266-19275, 2020 | 189 | 2020 |
| Plasma apolipoprotein A1 as a biomarker for Parkinson disease JK Qiang, YC Wong, A Siderowf, HI Hurtig, SX Xie, VMY Lee, ... Annals of neurology 74 (1), 119-127, 2013 | 141 | 2013 |
| Autophagosome dynamics in neurodegeneration at a glance YC Wong, ELF Holzbaur J Cell Sci 128 (7), 1259-1267, 2015 | 140 | 2015 |
| Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease S Kim, YC Wong, F Gao, D Krainc Nature communications 12 (1), 1807, 2021 | 122 | 2021 |
| Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients C Valdez, YC Wong, M Schwake, G Bu, ZK Wszolek, D Krainc Human molecular genetics 26 (24), 4861-4872, 2017 | 114 | 2017 |
| Increased lysosomal exocytosis induced by lysosomal Ca2+ channel agonists protects human dopaminergic neurons from α-synuclein toxicity T Tsunemi, T Perez-Rosello, Y Ishiguro, A Yoroisaka, S Jeon, K Hamada, ... Journal of Neuroscience 39 (29), 5760-5772, 2019 | 109 | 2019 |
| Analysis of blood-based gene expression in idiopathic Parkinson disease R Shamir, C Klein, D Amar, EJ Vollstedt, M Bonin, M Usenovic, YC Wong, ... Neurology 89 (16), 1676-1683, 2017 | 109 | 2017 |
| Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals? YC Wong, K Luk, K Purtell, S Burke Nanni, AJ Stoessl, LE Trudeau, Z Yue, ... Movement Disorders 34 (10), 1406-1422, 2019 | 92 | 2019 |
| Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria YC Wong, ELF Holzbaur Autophagy 11 (2), 422-424, 2015 | 90 | 2015 |
| Lysosomal regulation of inter-mitochondrial contact fate and motility in Charcot-Marie-Tooth Type 2 YC Wong, W Peng, D Krainc Developmental Cell 50 (3), 339-354. e4, 2019 | 68 | 2019 |
| Lysosomal trafficking defects link Parkinson's disease with Gaucher's disease YC Wong, D Krainc Movement Disorders 31 (11), 1610-1618, 2016 | 66 | 2016 |
| The Parkinson’s disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking MJ Kim, HX Deng, YC Wong, T Siddique, D Krainc Human molecular genetics 26 (4), 729-741, 2017 | 51 | 2017 |
