| Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response MJ Sikora, KL Cooper, A Bahreini, S Luthra, G Wang, UR Chandran, ... Cancer research 74 (5), 1463-1474, 2014 | 145 | 2014 |
| Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance LA Martin, R Ribas, N Simigdala, E Schuster, S Pancholi, T Tenev, ... Nature communications 8 (1), 1865, 2017 | 136 | 2017 |
| The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6 NT Snider, MJ Sikora, C Sridar, TJ Feuerstein, JM Rae, PF Hollenberg Journal of Pharmacology and Experimental Therapeutics 327 (2), 538-545, 2008 | 104 | 2008 |
| The androgen metabolite 5α-androstane-3β, 17β-diol (3βAdiol) induces breast cancer growth via estrogen receptor: implications for aromatase inhibitor resistance MJ Sikora, KE Cordero, JM Larios, MD Johnson, ME Lippman, JM Rae Breast cancer research and treatment 115 (2), 289-296, 2009 | 100* | 2009 |
| Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients JM Rae, MJ Sikora, NL Henry, L Li, S Kim, S Oesterreich, TC Skaar, ... The pharmacogenomics journal 9 (4), 258-264, 2009 | 92 | 2009 |
| Activation of Wnt signaling promotes olaparib resistant ovarian cancer TM Yamamoto, A McMellen, ZL Watson, J Aguilera, R Ferguson, ... Molecular carcinogenesis 58 (10), 1770-1782, 2019 | 88 | 2019 |
| Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer T Du, MJ Sikora, KM Levine, N Tasdemir, RB Riggins, SG Wendell, ... Breast Cancer Research 20, 1-15, 2018 | 83 | 2018 |
| Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort N Lynn Henry, JM Rae, L Li, F Azzouz, TC Skaar, Z Desta, MJ Sikora, ... Breast cancer research and treatment 117, 571-575, 2009 | 82 | 2009 |
| Endocrine response phenotypes are altered by charcoal-stripped serum variability MJ Sikora, MD Johnson, AV Lee, S Oesterreich Endocrinology 157 (10), 3760-3766, 2016 | 76 | 2016 |
| WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines MJ Sikora, BM Jacobsen, K Levine, J Chen, NE Davidson, AV Lee, ... Breast Cancer Research 18, 1-16, 2016 | 71 | 2016 |
| Comprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D cultures N Tasdemir, EA Bossart, Z Li, L Zhu, MJ Sikora, KM Levine, BM Jacobsen, ... Cancer research 78 (21), 6209-6222, 2018 | 67 | 2018 |
| Invasive lobular carcinoma of the breast: patient response to systemic endocrine therapy and hormone response in model systems MJ Sikora, RC Jankowitz, DJ Dabbs, S Oesterreich Steroids 78 (6), 568-575, 2013 | 65 | 2013 |
| Active estrogen receptor-alpha signaling in ovarian cancer models and clinical specimens CL Andersen, MJ Sikora, MM Boisen, T Ma, A Christie, G Tseng, Y Park, ... Clinical Cancer Research 23 (14), 3802-3812, 2017 | 57 | 2017 |
| FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype KM Levine, N Priedigkeit, A Basudan, N Tasdemir, MJ Sikora, ES Sokol, ... NPJ breast cancer 5 (1), 19, 2019 | 54 | 2019 |
| Efavirenz directly modulates the oestrogen receptor and induces breast cancer cell growth MJ Sikora, JM Rae, MD Johnson, Z Desta HIV medicine 11 (9), 603-607, 2010 | 47 | 2010 |
| Mechanisms of estrogen-independent breast cancer growth driven by low estrogen concentrations are unique versus complete estrogen deprivation MJ Sikora, V Strumba, ME Lippman, MD Johnson, JM Rae Breast cancer research and treatment 134, 1027-1039, 2012 | 41 | 2012 |
| High intratumoral stromal content defines reactive breast cancer as a low-risk breast cancer subtype JB Dennison, M Shahmoradgoli, W Liu, Z Ju, F Meric-Bernstam, ... Clinical Cancer Research 22 (20), 5068-5078, 2016 | 40 | 2016 |
| The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval KR Jordan, MJ Sikora, JE Slansky, A Minic, JK Richer, MR Moroney, J Hu, ... Clinical Cancer Research 26 (23), 6362-6373, 2020 | 38 | 2020 |
| Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion DM Rao, MT Shackleford, EK Bordeaux, JL Sottnik, RL Ferguson, ... Journal of Biological Chemistry 294 (52), 19950-19966, 2019 | 32* | 2019 |
| CYP2D6 genotype is not associated with survival in breast cancer patients treated with tamoxifen: results from a population-based study DL Hertz, KM Kidwell, SG Hilsenbeck, S Oesterreich, CK Osborne, ... Breast cancer research and treatment 166, 277-287, 2017 | 30 | 2017 |
Amir BahreiniUniversity of Pittsburgh; KaryoGenVerified email at pitt.edu
