| Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation V Pooladanda, S Thatikonda, S Bale, B Pattnaik, DK Sigalapalli, ... Cell death & disease 10 (2), 81, 2019 | 112 | 2019 |
| Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation S Thatikonda, V Pooladanda, DK Sigalapalli, C Godugu Cell death & disease 11 (1), 21, 2020 | 85 | 2020 |
| An overview on applications of SwissADME web tool in the design and development of anticancer, antitubercular and antimicrobial agents: A medicinal chemist's perspective B Bakchi, AD Krishna, E Sreecharan, VBJ Ganesh, M Niharika, ... Journal of Molecular Structure 1259, 132712, 2022 | 74 | 2022 |
| Synthesis of thiazole linked indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors SD Guggilapu, L Guntuku, TS Reddy, A Nagarsenkar, DK Sigalapalli, ... European Journal of Medicinal Chemistry 138, 83-95, 2017 | 56 | 2017 |
| Synthesis and α-glucosidase inhibition activity of dihydroxy pyrrolidines S Kasturi, S Surarapu, S Uppalanchi, JS Anireddy, S Dwivedi, ... Bioorganic & Medicinal Chemistry Letters 27 (12), 2818-2823, 2017 | 54 | 2017 |
| Synthesis and biological evaluation of curcumin inspired imidazo [1, 2-a] pyridine analogues as tubulin polymerization inhibitors PVS Ramya, L Guntuku, S Angapelly, CS Digwal, UJ Lakshmi, ... European journal of medicinal chemistry 143, 216-231, 2018 | 48 | 2018 |
| Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors J Kode, J Kovvuri, B Nagaraju, S Jadhav, M Barkume, S Sen, ... Bioorganic Chemistry 105, 104447, 2020 | 41 | 2020 |
| Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1, 2, 3-triazole chalcone hybrids P Singh, B Swain, PS Thacker, DK Sigalapalli, PP Yadav, A Angeli, ... Bioorganic chemistry 99, 103839, 2020 | 35 | 2020 |
| Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition … DK Sigalapalli, V Pooladanda, P Singh, M Kadagathur, SD Guggilapu, ... Bioorganic chemistry 92, 103188, 2019 | 35 | 2019 |
| Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity R Tokala, S Sana, UJ Lakshmi, P Sankarana, DK Sigalapalli, N Gadewal, ... Bioorganic Chemistry 105, 104357, 2020 | 33 | 2020 |
| Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors L Zang, SM Kondengaden, Q Zhang, X Li, DK Sigalapalli, ... Oncotarget 8 (38), 63187, 2017 | 33 | 2017 |
| Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction R Tokala, S Mahajan, G Kiranmai, DK Sigalapalli, S Sana, SE John, ... Bioorganic Chemistry 106, 104481, 2021 | 31 | 2021 |
| Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3, 4-dihydroxy piperidines SP Kasturi, S Surarapu, S Uppalanchi, S Dwivedi, P Yogeeswari, ... European Journal of Medicinal Chemistry 150, 39-52, 2018 | 31 | 2018 |
| Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies M Kadagathur, GP Devi, P Grewal, DK Sigalapalli, PN Makhal, ... Bioorganic Chemistry 99, 103629, 2020 | 29 | 2020 |
| Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents RR Bhandare, CS Munikrishnappa, GVS Kumar, SK Konidala, ... Journal of Saudi Chemical Society 26 (3), 101447, 2022 | 28 | 2022 |
| Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability KL Manasa, S Thatikonda, DK Sigalapalli, A Sagar, G Kiranmai, AM Kalle, ... Bioorganic Chemistry 101, 103983, 2020 | 22 | 2020 |
| Synthesis and biological evaluation of novel imidazo [1, 2-a] pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA … DK Sigalapalli, G Kiranmai, GP Devi, R Tokala, S Sana, C Tripura, ... Bioorganic & Medicinal Chemistry 43, 116277, 2021 | 16 | 2021 |
| Novel chromenyl-based 2-iminothiazolidin-4-one derivatives as tubulin polymerization inhibitors: Design, synthesis, biological evaluation and molecular modelling studies DK Sigalapalli, V Pooladanda, M Kadagathur, SD Guggilapu, JL Uppu, ... Journal of Molecular Structure 1225, 128847, 2021 | 16 | 2021 |
| Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors M Kadagathur, AS Shaikh, B Panda, J George, R Phanindranath, ... Bioorganic Chemistry 122, 105706, 2022 | 15 | 2022 |
| Targeting tubulin polymerization and DNA binding of 4-thiazolidinone–umbelliferone hybrids: synthesis and cytotoxicity evaluation DK Sigalapalli, G Kiranmai, R Tokala, C Tripura, R Ambatwar, ... New Journal of Chemistry 45 (40), 18908-18923, 2021 | 12 | 2021 |
Dr Bathini Nagendra BabuSenior Scientist, CSIR-Indian Institute of Chemical TechnologyVerified email at iict.res.in
