N-terminal domain of Bombyx mori fibroin mediates the assembly of silk in response to pH decrease YX He, NN Zhang, WF Li, N Jia, BY Chen, K Zhou, J Zhang, Y Chen, ... Journal of molecular biology 418 (3-4), 197-207, 2012 | 149 | 2012 |
Type III-A CRISPR-Cas Csm complexes: assembly, periodic RNA cleavage, DNase activity regulation, and autoimmunity N Jia, CY Mo, C Wang, ET Eng, LA Marraffini, DJ Patel Molecular cell 73 (2), 264-277. e5, 2019 | 92 | 2019 |
CRISPR-Cas III-A Csm6 CARF domain is a ring nuclease triggering stepwise cA4 cleavage with ApA> p formation terminating RNase activity N Jia, R Jones, G Yang, O Ouerfelli, DJ Patel Molecular cell 75 (5), 944-956. e6, 2019 | 91 | 2019 |
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity AJ Meeske, N Jia, AK Cassel, A Kozlova, J Liao, M Wiedmann, DJ Patel, ... Science 369 (6499), 54-59, 2020 | 88 | 2020 |
Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins N Jia, DJ Patel Nature Reviews Molecular Cell Biology 22 (8), 563-579, 2021 | 63 | 2021 |
Structural basis for receptor recognition and pore formation of a zebrafish aerolysin‐like protein N Jia, N Liu, W Cheng, YL Jiang, H Sun, LL Chen, J Peng, Y Zhang, ... EMBO reports 17 (2), 235-248, 2016 | 62 | 2016 |
Second messenger cA4 formation within the composite Csm1 palm pocket of type III-A CRISPR-Cas Csm complex and its release path N Jia, R Jones, G Sukenick, DJ Patel Molecular cell 75 (5), 933-943. e6, 2019 | 42 | 2019 |
Structure–function insights into the initial step of DNA integration by a CRISPR–Cas–Transposon complex N Jia, W Xie, MJ de la Cruz, ET Eng, DJ Patel Cell Research 30 (2), 182-184, 2020 | 34 | 2020 |
Genetic differentiation of Trachurus japonicus from the Northwestern Pacific based on the mitochondrial DNA control region N Song, N Jia, T Yanagimoto, L Lin, T Gao mitochondrial DNA 24 (6), 705-712, 2013 | 28 | 2013 |
Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori K Zhou, N Jia, C Hu, YL Jiang, JP Yang, Y Chen, S Li, WF Li, CZ Zhou Proteins: Structure, Function, and Bioinformatics 82 (11), 3224-3229, 2014 | 20 | 2014 |
The pore-forming protein Aep1 is an innate immune molecule that prevents zebrafish from bacterial infection LL Chen, J Xie, DD Cao, N Jia, YJ Li, H Sun, WF Li, B Hu, Y Chen, ... Developmental & Comparative Immunology 82, 49-54, 2018 | 18 | 2018 |
Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection N Jia, MC Unciuleac, C Xue, EC Greene, DJ Patel, S Shuman Proceedings of the National Academy of Sciences 116 (49), 24507-24516, 2019 | 17 | 2019 |
Bacterial origins of cyclic nucleotide-activated antiviral immune signaling DJ Patel, Y Yu, N Jia Molecular cell 82 (24), 4591-4610, 2022 | 11 | 2022 |
Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase N Cui, JT Zhang, Z Li, XY Liu, C Wang, H Huang, N Jia Nature Communications 13 (1), 7549, 2022 | 8 | 2022 |
Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment N Cui, JT Zhang, Y Liu, Y Liu, XY Liu, C Wang, H Huang, N Jia Molecular Cell 83 (14), 2493-2508. e5, 2023 | 5 | 2023 |
Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system JT Zhang, XY Wei, N Cui, R Tian, N Jia Nature Chemical Biology 20 (4), 503-511, 2024 | 1 | 2024 |
Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05 Z Duan, X Zhang, JT Zhang, S Li, R Liu, J Sun, Q Zhao, N Jia, N Jia, ... Cell Discovery 9 (1), 117, 2023 | 1 | 2023 |
Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system JT Zhang, XY Liu, Z Li, XY Wei, XY Song, N Cui, J Zhong, H Li, N Jia Nature Communications 15 (1), 1-14, 2024 | | 2024 |
Structure-based evolutionary relationship between IscB and Cas9 N Jia, DJ Patel Cell Research 32 (10), 875-877, 2022 | | 2022 |