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Kuchuan Chen
Kuchuan Chen
Boston Children's Hospital
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
Drosophila tools and assays for the study of human diseases
B Ugur, K Chen, HJ Bellen
Disease models & mechanisms 9 (3), 235-244, 2016
5042016
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ...
Nature neuroscience 22 (2), 167-179, 2019
4002019
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases
S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ...
Cell 159 (1), 200-214, 2014
3992014
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila
S Nagarkar-Jaiswal, PT Lee, ME Campbell, K Chen, S Anguiano-Zarate, ...
elife 4, e05338, 2015
3922015
Phospholipase PLA2G6, a Parkinsonism-associated gene, affects Vps26 and Vps35, retromer function, and ceramide levels, similar to α-synuclein gain
G Lin, PT Lee, K Chen, D Mao, KL Tan, Z Zuo, WW Lin, L Wang, HJ Bellen
Cell metabolism 28 (4), 605-618. e6, 2018
1482018
Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production
H Sandoval, CK Yao, K Chen, M Jaiswal, T Donti, YQ Lin, V Bayat, ...
Elife 3, e03558, 2014
1112014
Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration
K Chen, G Lin, NA Haelterman, TSY Ho, T Li, Z Li, L Duraine, BH Graham, ...
Elife 5, e16043, 2016
762016
Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission
YC Chen, YQ Lin, S Banerjee, K Venken, J Li, A Ismat, K Chen, L Duraine, ...
Journal of neuroscience 32 (45), 16018-16030, 2012
762012
A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission
CO Wong, K Chen, YQ Lin, Y Chao, L Duraine, Z Lu, WH Yoon, ...
Neuron 84 (4), 764-777, 2014
732014
Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals
K Chen, TSY Ho, G Lin, KL Tan, MN Rasband, HJ Bellen
Elife 5, e20732, 2016
652016
Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11
WL Charng, S Yamamoto, M Jaiswal, V Bayat, B Xiong, K Zhang, ...
PLoS biology 12 (1), e1001777, 2014
542014
Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation
X Huang, KCD Roet, L Zhang, A Brault, AP Berg, AB Jefferson, ...
Cell reports 35 (10), 2021
342021
Ubr3, a novel modulator of Hh signaling affects the degradation of Costal-2 and Kif7 through poly-ubiquitination
T Li, J Fan, B Blanco-Sánchez, N Giagtzoglou, G Lin, S Yamamoto, ...
PLoS Genetics 12 (5), e1006054, 2016
182016
Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9
HK Tang, KC Chen, GG Liou, SC Cheng, CH Chien, HY Tang, LH Huang, ...
Febs Letters 585 (21), 3409-3414, 2011
152011
Screening for axon regeneration promoting compounds with human iPSC-derived motor neurons
TSY Ho, JT Hees, Z Xu, R Kawaguchi, NP Biscola, DG Taub, K Chen, ...
bioRxiv, 2021.11. 02.466937, 2021
22021
A TRPV Channel in Drosophila Motor Neurons Regulates Presynaptic Resting Ca 2 Levels, Synapse Growth, and Synaptic Transmission
CO Wong, YQ Lin, K Chen, Y Chao, L Duraine, WH Yoon, JM Sullivan, ...
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