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Rakan El-Mayta
Rakan El-Mayta
Department of Medicine, University of Pennsylvania
Verified email at sas.upenn.edu
Title
Cited by
Cited by
Year
Scalable mRNA and siRNA lipid nanoparticle production using a parallelized microfluidic device
SJ Shepherd, CC Warzecha, S Yadavali, R El-Mayta, MG Alameh, ...
Nano Letters 21 (13), 5671-5680, 2021
1402021
Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening
PPG Guimaraes, R Zhang, R Spektor, M Tan, A Chung, MM Billingsley, ...
Journal of Controlled Release 316, 404-417, 2019
1322019
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver
R Zhang, R El-Mayta, TJ Murdoch, CC Warzecha, MM Billingsley, ...
Biomaterials Science 9 (4), 1449-1463, 2021
1072021
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
X Han, N Gong, L Xue, MM Billingsley, R El-Mayta, SJ Shepherd, ...
Nature Communications 14 (1), 75, 2023
412023
Delivery technologies to engineer natural killer cells for cancer immunotherapy
R El-Mayta, Z Zhang, AG Hamilton, MJ Mitchell
Cancer Gene Therapy 28 (9), 947-959, 2021
252021
A Nanoparticle Platform for Accelerated In Vivo Oral Delivery Screening of Nucleic Acids
R El‐Mayta, R Zhang, SJ Shepherd, F Wang, MM Billingsley, V Dudkin, ...
Advanced Therapeutics 4 (1), 2000111, 2021
212021
Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
K Butowska, X Han, N Gong, R El-Mayta, RM Haley, L Xue, W Zhong, ...
Acta Pharmaceutica Sinica B 13 (4), 1429-1437, 2023
192023
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ...
Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023
162023
In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy
PPG Guimarães, CG Figueroa-Espada, RS Riley, N Gong, L Xue, ...
Proceedings of the National Academy of Sciences 120 (25), e2215711120, 2023
152023
Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction
M Huang, F Yang, D Zhang, M Lin, H Duan, R El-Mayta, L Zhang, L Qin, ...
Nature Cardiovascular Research 1 (4), 372-388, 2022
112022
Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing
R El-Mayta, MS Padilla, MM Billingsley, X Han, MJ Mitchell
JoVE (Journal of Visualized Experiments), e64810, 2023
92023
In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity
N Gong, X Han, L Xue, R El-Mayta, AE Metzloff, MM Billingsley, ...
Nature Materials 22 (12), 1571-1580, 2023
82023
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ...
Small, 2304378, 2023
62023
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery
SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ...
Theranostics 14 (1), 1, 2024
32024
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models
L Xue, AG Hamilton, G Zhao, Z Xiao, R El-Mayta, X Han, N Gong, X Xiong, ...
Nature Communications 15 (1), 1884, 2024
12024
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma
F Yang, MN Akhtar, D Zhang, R El-Mayta, J Shin, JF Dorsey, L Zhang, ...
Science Advances 10 (9), eadj4678, 2024
2024
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors
X Han, J Xu, Y Xu, MG Alameh, L Xue, N Gong, R El-Mayta, R Palanki, ...
Nature Communications 15 (1), 1762, 2024
2024
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager
N Gong, X Han, L Xue, MM Billingsley, X Huang, R El-Mayta, J Qin, ...
Nature Biomedical Engineering, 1-16, 2024
2024
Generation of Efficient Lipid Nanoparticles for Liver-Directed Gene Therapy and Genome Editing
CC Warzecha, R El-Mayta, L Xue, L Wang, MJ Mitchell, JM Wilson
MOLECULAR THERAPY 30 (4), 213-213, 2022
2022
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