| Membrane active antimicrobial peptides: translating mechanistic insights to design J Li, JJ Koh, S Liu, R Lakshminarayanan, CS Verma, RW Beuerman Frontiers in neuroscience 11, 244777, 2017 | 560 | 2017 |
| Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting JJ Koh, S Qiu, H Zou, R Lakshminarayanan, J Li, X Zhou, C Tang, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (2), 834-844, 2013 | 204 | 2013 |
| Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections JJ Koh, S Lin, TT Aung, F Lim, H Zou, Y Bai, J Li, H Lin, LM Pang, WL Koh, ... Journal of medicinal chemistry 58 (2), 739-752, 2015 | 130 | 2015 |
| Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity H Zou, JJ Koh, J Li, S Qiu, TT Aung, H Lin, R Lakshminarayanan, X Dai, ... Journal of medicinal chemistry 56 (6), 2359-2373, 2013 | 115 | 2013 |
| Symmetrically substituted xanthone amphiphiles combat gram-positive bacterial resistance with enhanced membrane selectivity S Lin, JJ Koh, TT Aung, F Lim, J Li, H Zou, L Wang, R Lakshminarayanan, ... Journal of medicinal chemistry 60 (4), 1362-1378, 2017 | 77 | 2017 |
| Molecular simulations suggest how a branched antimicrobial peptide perturbs a bacterial membrane and enhances permeability J Li, S Liu, R Lakshminarayanan, Y Bai, K Pervushin, C Verma, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (3), 1112-1121, 2013 | 74 | 2013 |
| Solubilization of aromatic and hydrophobic moieties by arginine in aqueous solutions J Li, M Garg, D Shah, R Rajagopalan The Journal of chemical physics 133 (5), 2010 | 65 | 2010 |
| Nonpeptidic amphiphilic xanthone derivatives: structure–activity relationship and membrane-targeting properties JJ Koh, H Zou, S Lin, H Lin, RT Soh, FH Lim, WL Koh, J Li, ... Journal of medicinal chemistry 59 (1), 171-193, 2016 | 61 | 2016 |
| Computational methods and tools in antimicrobial peptide research PGA Aronica, LM Reid, N Desai, J Li, SJ Fox, S Yadahalli, JW Essex, ... Journal of Chemical Information and Modeling 61 (7), 3172-3196, 2021 | 57 | 2021 |
| Arginine–aromatic interactions and their effects on arginine‐induced solubilization of aromatic solutes and suppression of protein aggregation D Shah, J Li, AR Shaikh, R Rajagopalan Biotechnology progress 28 (1), 223-231, 2012 | 53 | 2012 |
| N-lipidated peptide dimers: effective antibacterial agents against gram-negative pathogens through lipopolysaccharide permeabilization JJ Koh, H Lin, V Caroline, YS Chew, LM Pang, TT Aung, J Li, ... Journal of medicinal chemistry 58 (16), 6533-6548, 2015 | 48 | 2015 |
| Progressive structuring of a branched antimicrobial peptide on the path to the inner membrane target Y Bai, S Liu, J Li, R Lakshminarayanan, P Sarawathi, C Tang, D Ho, ... Journal of Biological Chemistry 287 (32), 26606-26617, 2012 | 43 | 2012 |
| Synthetic multivalent antifungal peptides effective against fungi R Lakshminarayanan, S Liu, J Li, M Nandhakumar, TT Aung, E Goh, ... PLoS One 9 (2), e87730, 2014 | 42 | 2014 |
| A novel fragment based strategy for membrane active antimicrobials against MRSA J Li, S Liu, JJ Koh, H Zou, R Lakshminarayanan, Y Bai, K Pervushin, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (4), 1023-1031, 2015 | 40 | 2015 |
| Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the gram-negative bacteria R Lakshminarayanan, WX Tan, TT Aung, ETL Goh, N Muruganantham, ... Scientific reports 6 (1), 25905, 2016 | 35 | 2016 |
| Molecular dynamics simulations of a new branched antimicrobial peptide: A comparison of force fields J Li, R Lakshminarayanan, Y Bai, S Liu, L Zhou, K Pervushin, C Verma, ... The Journal of Chemical Physics 137 (21), 2012 | 29 | 2012 |
| Stabilization of peptides against proteolysis through disulfide-bridged conjugation with synthetic aromatics Y Chen, T Li, J Li, S Cheng, J Wang, C Verma, Y Zhao, C Wu Organic & Biomolecular Chemistry 15 (8), 1921-1929, 2017 | 22 | 2017 |
| Polymer-induced phase separation and crystallization in immunoglobulin G solutions J Li, R Rajagopalan, J Jiang The Journal of chemical physics 128 (20), 2008 | 22 | 2008 |
| Reactive metabolite-induced protein glutathionylation: a potentially novel mechanism underlying acetaminophen hepatotoxicity JCY Chan, ACK Soh, DYQ Kioh, J Li, C Verma, SK Koh, RW Beuerman, ... Molecular & Cellular Proteomics 17 (10), 2034-2050, 2018 | 19 | 2018 |
| Antimicrobial activity profiles of amphiphilic xanthone derivatives are a function of their molecular oligomerization JJ Koh, S Lin, Y Bai, WWL Sin, TT Aung, J Li, V Chandra, K Pervushin, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (11), 2281-2298, 2018 | 18 | 2018 |
