CRISPR-Cas9–mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes H Takeda, S Kataoka, M Nakayama, MAE Ali, H Oshima, D Yamamoto, ... Proceedings of the National Academy of Sciences 116 (31), 15635-15644, 2019 | 112 | 2019 |
Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance AM Hegazy, D Yamada, M Kobayashi, S Kohno, M Ueno, MAE Ali, K Ohta, ... Journal of Biological Chemistry 291 (41), 21496-21509, 2016 | 41 | 2016 |
Hematopoietic stem and progenitor cells exhibit stage-specific translational programs via mTOR-and CDK1-dependent mechanisms CC Spevak, HK Elias, L Kannan, MAE Ali, GH Martin, S Selvaraj, WS Eng, ... Cell stem cell 26 (5), 755-765. e7, 2020 | 29 | 2020 |
Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells S Tanaka, M Nakada, D Yamada, I Nakano, T Todo, Y Ino, T Hoshii, ... Journal of neuro-oncology 121, 239-250, 2015 | 29 | 2015 |
Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals D Yamada, T Hoshii, S Tanaka, AM Hegazy, M Kobayashi, Y Tadokoro, ... The journal of biochemistry 155 (4), 227-233, 2014 | 26 | 2014 |
Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression MAE Ali, K Fuse, Y Tadokoro, T Hoshii, M Ueno, M Kobayashi, N Nomura, ... Scientific reports 7 (1), 11442, 2017 | 24 | 2017 |
Abundant nucleostemin expression supports the undifferentiated properties of germ cell tumors N Uema, T Ooshio, K Harada, M Naito, K Naka, T Hoshii, Y Tadokoro, ... The American Journal of Pathology 183 (2), 592-603, 2013 | 13 | 2013 |
Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients MAE Ali, K Naka, A Yoshida, K Fuse, A Kasada, T Hoshii, Y Tadokoro, ... Biochemical and biophysical research communications 450 (1), 837-843, 2014 | 9 | 2014 |
High-valency anti-CD99 antibodies toward the treatment of T cell acute lymphoblastic leukemia LA Romero, T Hattori, MAE Ali, G Ketavarapu, A Koide, CY Park, S Koide Journal of molecular biology 434 (5), 167402, 2022 | 5 | 2022 |
A new view of hematopoiesis during inflammation MAE Ali, CY Park Blood, The Journal of the American Society of Hematology 136 (10), 1117-1118, 2020 | 2 | 2020 |
The Effect of Diet Composition on the Post-operative Outcomes of Roux-en-Y Gastric Bypass in Mice M Stevenson, A Srivastava, M Nacher, C Hall, T Palaia, J Lee, CL Zhao, ... Obesity surgery, 1-17, 2024 | | 2024 |
Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice R Sun, S Guo, Y Shuda, AB Chakka, LH Rigatti, G Zhao, MAE Ali, CY Park, ... Plos one 18 (5), e0282722, 2023 | | 2023 |
Functional and Molecular Heterogeneity of Aging Hematopoietic Stem Cells S Chakraborty, HK Elias, MAE Ali, I Beerman, CY Park Blood 140 (Supplement 1), 2854-2855, 2022 | | 2022 |
Identification of Old HSCs with Preserved Self-Renewal and Long-Term Reconstitution Potential HK Elias, JY Shin, MAE Ali, S Chakraborty, CJ Ha, I Dolgalev, C Konishi, ... Blood 134, 2479, 2019 | | 2019 |
Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells HK Elias, C Spevak, L Kannan, MAE Ali, GH Martin, S Selvaraj, WS Eng, ... Blood 134, 1180, 2019 | | 2019 |