A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy M Pang, LI Ma, R Gong, E Tolbert, H Mao, M Ponnusamy, YE Chin, H Yan, ... Kidney international 78 (3), 257-268, 2010 | 291 | 2010 |
Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis N Liu, JK Guo, M Pang, E Tolbert, M Ponnusamy, R Gong, G Bayliss, ... Journal of the American Society of Nephrology 23 (5), 854-867, 2012 | 170 | 2012 |
Enhancer of zeste homolog 2 inhibition attenuates renal fibrosis by maintaining Smad7 and phosphatase and tensin homolog expression X Zhou, X Zang, M Ponnusamy, MV Masucci, E Tolbert, R Gong, TC Zhao, ... Journal of the American Society of Nephrology 27 (7), 2092-2108, 2016 | 166 | 2016 |
Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES R Gong, A Rifai, EM Tolbert, P Biswas, JN Centracchio, LD Dworkin Journal of the American Society of Nephrology 15 (11), 2868-2881, 2004 | 155 | 2004 |
Hepatocyte growth factor modulates matrix metalloproteinases and plasminogen activator/plasmin proteolytic pathways in progressive renal interstitial fibrosis R Gong, A Rifai, EM Tolbert, JN Centracchio, LD Dworkin Journal of the American Society of Nephrology 14 (12), 3047-3060, 2003 | 146 | 2003 |
Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury J Tang, N Liu, E Tolbert, M Ponnusamy, L Ma, R Gong, G Bayliss, H Yan, ... The American journal of pathology 183 (1), 160-172, 2013 | 130 | 2013 |
Hepatocyte growth factor suppresses proinflammatory NFκB activation through GSK3β inactivation in renal tubular epithelial cells R Gong, A Rifai, Y Ge, S Chen, LD Dworkin Journal of Biological Chemistry 283 (12), 7401-7410, 2008 | 118 | 2008 |
Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium R Gong, A Rifai, LD Dworkin Journal of the American Society of Nephrology 17 (9), 2464-2473, 2006 | 116 | 2006 |
Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury LD Dworkin, R Gong, E Tolbert, J Centracchio, N Yano, AR Zanabli, ... Kidney international 65 (2), 409-419, 2004 | 111 | 2004 |
The renaissance of corticotropin therapy in proteinuric nephropathies R Gong Nature Reviews Nephrology 8 (2), 122-128, 2012 | 106 | 2012 |
Long noncoding RNA: an emerging player in diabetes and diabetic kidney disease J Guo, Z Liu, R Gong Clinical Science 133 (12), 1321-1339, 2019 | 96 | 2019 |
The ageing kidney: Molecular mechanisms and clinical implications Y Fang, AY Gong, ST Haller, LD Dworkin, Z Liu, R Gong Ageing research reviews 63, 101151, 2020 | 90 | 2020 |
Delayed administration of a single dose of lithium promotes recovery from AKI H Bao, Y Ge, Z Wang, S Zhuang, L Dworkin, A Peng, R Gong Journal of the American Society of Nephrology 25 (3), 488-500, 2014 | 89 | 2014 |
Blocking sirtuin 1 and 2 inhibits renal interstitial fibroblast activation and attenuates renal interstitial fibrosis in obstructive nephropathy M Ponnusamy, X Zhou, Y Yan, J Tang, E Tolbert, TC Zhao, R Gong, ... Journal of Pharmacology and Experimental Therapeutics 350 (2), 243-256, 2014 | 88 | 2014 |
Candesartan suppresses chronic renal inflammation by a novel antioxidant action independent of AT1R blockade S Chen, Y Ge, J Si, A Rifai, LD Dworkin, R Gong Kidney international 74 (9), 1128-1138, 2008 | 87 | 2008 |
GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition M Lu, P Wang, Y Qiao, C Jiang, Y Ge, B Flickinger, DK Malhotra, ... Redox biology 26, 101275, 2019 | 86 | 2019 |
What we need to know about the effect of lithium on the kidney R Gong, P Wang, L Dworkin American Journal of Physiology-Renal Physiology 311 (6), F1168-F1171, 2016 | 85 | 2016 |
Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C Y Jiang, H Bao, Y Ge, W Tang, D Cheng, K Luo, G Gong, R Gong Gut 64 (1), 168-179, 2015 | 85 | 2015 |
Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury H Bao, Y Ge, S Zhuang, LD Dworkin, Z Liu, R Gong Kidney international 81 (7), 662-673, 2012 | 80 | 2012 |
Genetic and pharmacologic targeting of glycogen synthase kinase 3β reinforces the Nrf2 antioxidant defense against podocytopathy S Zhou, P Wang, Y Qiao, Y Ge, Y Wang, S Quan, R Yao, S Zhuang, ... Journal of the American Society of Nephrology 27 (8), 2289-2308, 2016 | 78 | 2016 |