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Nicholas R. Klug
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Contractile pericytes determine the direction of blood flow at capillary junctions
AL Gonzales, NR Klug, A Moshkforoush, JC Lee, FK Lee, B Shui, ...
Proceedings of the National Academy of Sciences 117 (43), 27022-27033, 2020
1472020
Piezo1 is a mechanosensor channel in central nervous system capillaries
OF Harraz, NR Klug, AJ Senatore, DC Hill-Eubanks, MT Nelson
Circulation research 130 (10), 1531-1546, 2022
492022
Reducing hypermuscularization of the transitional segment between arterioles and capillaries protects against spontaneous intracerebral hemorrhage
J Ratelade, NR Klug, D Lombardi, MKSC Angelim, F Dabertrand, ...
Circulation 141 (25), 2078-2094, 2020
472020
Ischemic factor-induced increases in cerebral microvascular endothelial cell Na/H exchange activity and abundance: evidence for involvement of ERK1/2 MAP kinase
N Yuen, TI Lam, BK Wallace, NR Klug, SE Anderson, ME O'Donnell
American Journal of Physiology-Cell Physiology 306 (10), C931-C942, 2014
472014
Adenosine signaling activates ATP-sensitive K+ channels in endothelial cells and pericytes in CNS capillaries
M Sancho, NR Klug, A Mughal, M Koide, S Huerta de la Cruz, TJ Heppner, ...
Science signaling 15 (727), eabl5405, 2022
362022
Kv2. 1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle
SC O’Dwyer, S Palacio, C Matsumoto, L Guarina, NR Klug, S Tajada, ...
Proceedings of the National Academy of Sciences 117 (7), 3858-3866, 2020
342020
Measurement of energy expenditure while playing exergames at a self-selected intensity
LH Bryan, S Jarvis, RK Nicholas, T Gonzalez, B Barsaga, RS Shannon, ...
The open sports sciences journal 5, 1, 2012
312012
High glucose-induced effects on Na+-K+-2Cl cotransport and Na+/H+ exchange of blood-brain barrier endothelial cells: involvement of SGK1, PKCβII, and …
NR Klug, OV Chechneva, BY Hung, ME O’Donnell
American Journal of Physiology-Cell Physiology 320 (4), C619-C634, 2021
132021
Intraluminal pressure elevates intracellular calcium and contracts CNS pericytes: role of voltage-dependent calcium channels
NR Klug, M Sancho, AL Gonzales, TJ Heppner, RIC O’Brien, ...
Proceedings of the National Academy of Sciences 120 (9), e2216421120, 2023
112023
Fitness assessment comparison between the “Jackie Chan action run” videogame, 1-mile run/walk, and the PACER
B Haddock, S Siegel, P Costa, S Jarvis, N Klug, E Medina Jr, L Wilkin
GAMES FOR HEALTH: Research, Development, and Clinical Applications 1 (3 …, 2012
82012
Piezo1 is a mechanosensor channel in CNS capillaries: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle
OF Harraz, NR Klug, A Senatore, M Koide, MT Nelson
Journal of General Physiology 154 (9), e2021ecc12, 2021
52021
Electro-Metabolic Sensing Through Capillary ATP-Sensitive K+ Channels and Adenosine to Control Cerebral Blood Flow
M Sancho, NR Klug, A Mughal, TJ Heppner, D Hill-Eubanks, MT Nelson
bioRxiv, 2021.03. 12.435152, 2021
52021
Hyperglycemia‐increased activity of blood‐brain barrier Na‐K‐Cl cotransport and Na/H exchange involves SGK1 and PKCβII (893.35)
O Chechneva, N Klug, N Yuen, M O'Donnell
The FASEB Journal 28, 893.35, 2014
32014
Distinct potassium channel types in brain capillary pericytes
M Sancho, NR Klug, OF Harraz, D Hill-Eubanks, MT Nelson
Biophysical Journal, 2024
12024
Hyperglycemia‐induced Increases in Na Transporter Abundance and Activity in Blood‐Brain Barrier Endothelial Cells: Involvement of SGK1, PKCβII and SPAK/OSR1
NR Klug, BY Hung, GT Bui, ME O'Donnell
The FASEB Journal 31, 1007.14-1007.14, 2017
12017
Hyperglycemia‐induced Elevation of NKCC1 Expression in Blood Brain Barrier Endothelial Cells: Greater Effect of Intermittent Versus Sustained Exposures
NR Klug, JT Raposa, MA Riley, ME O'Donnell
The FASEB Journal 30, 1224.20-1224.20, 2016
12016
Assessment of Functional Characteristics of Small Arterioles and Capillaries Using an Intact Dura Mater Preparation
A Arnold, A Sprouse-Blum, M Nelson, N Klug
Physiology 38 (S1), 5792350, 2023
2023
Enhanced Vascular Contractility Following Secondhand Smoke Exposure: A Pathological “Double-hit” to Critical Smooth Muscle Ion Channels
NR Klug, MT Nelson
Function 3 (1), zqab061, 2022
2022
Channels and Transporters in Cell Signaling: High glucose-induced effects on Na+-K+-2Cl− cotransport and Na+/H+ exchange of blood-brain barrier endothelial cells: involvement …
NR Klug, OV Chechneva, BY Hung, ME O’Donnell
American Journal of Physiology-Cell Physiology 320 (4), C619, 2021
2021
BIN1 clusters CaV1.2 channels in vascular smooth muscle
S O'Dwyer, C Moreno, N Klug, LF Santana
The FASEB Journal 33 (S1), 827.2-827.2, 2019
2019
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