| Somatic mutations of calreticulin in myeloproliferative neoplasms T Klampfl, H Gisslinger, AS Harutyunyan, H Nivarthi, E Rumi, JD Milosevic, ... New England Journal of Medicine 369 (25), 2379-2390, 2013 | 2439 | 2013 |
| A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease A Zimprich, A Benet-Pagès, W Struhal, E Graf, SH Eck, MN Offman, ... The American Journal of Human Genetics 89 (1), 168-175, 2011 | 1089 | 2011 |
| JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes E Rumi, D Pietra, V Ferretti, T Klampfl, AS Harutyunyan, JD Milosevic, ... Blood 123 (10), 1544-1551, 2014 | 771 | 2014 |
| The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape DN Weinberg, S Papillon-Cavanagh, H Chen, Y Yue, X Chen, ... Nature 573 (7773), 281-286, 2019 | 447 | 2019 |
| A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms D Olcaydu, A Harutyunyan, R Jäger, T Berg, B Gisslinger, I Pabinger, ... Nature genetics 41 (4), 450-454, 2009 | 435 | 2009 |
| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 300 | 2019 |
| H3. 3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ... Cancer cell 32 (5), 684-700. e9, 2017 | 256 | 2017 |
| p53 lesions in leukemic transformation A Harutyunyan, T Klampfl, M Cazzola, R Kralovics New England Journal of Medicine 364 (5), 488-490, 2011 | 254 | 2011 |
| Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression T Klampfl, A Harutyunyan, T Berg, B Gisslinger, M Schalling, K Bagienski, ... Blood 118 (1), 167-176, 2011 | 205 | 2011 |
| Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ... Nature Communications 6, 2015 | 194 | 2015 |
| Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 189 | 2019 |
| Deletions of the transcription factor Ikaros in myeloproliferative neoplasms R Jäger, H Gisslinger, F Passamonti, E Rumi, T Berg, B Gisslinger, ... Leukemia 24 (7), 1290-1298, 2010 | 179 | 2010 |
| Histone H3. 3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 136 | 2020 |
| Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies A Puda, JD Milosevic, T Berg, T Klampfl, AS Harutyunyan, B Gisslinger, ... American journal of hematology 87 (3), 245-250, 2012 | 130 | 2012 |
| H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2 SU Jain, AQ Rashoff, SD Krabbenhoft, D Hoelper, TJ Do, TJ Gibson, ... Molecular cell 80 (4), 726-735. e7, 2020 | 112 | 2020 |
| CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis E Rumi, AS Harutyunyan, D Pietra, JD Milosevic, IC Casetti, M Bellini, ... Blood 123 (15), 2416-2419, 2014 | 106 | 2014 |
| Clinical significance of genetic aberrations in secondary acute myeloid leukemia JD Milosevic, A Puda, L Malcovati, T Berg, M Hofbauer, A Stukalov, ... American journal of hematology 87 (11), 1010-1016, 2012 | 102 | 2012 |
| Population genetics of familial Mediterranean fever: a review L Yepiskoposyan, A Harutyunyan European Journal of Human Genetics 15 (9), 911-916, 2007 | 97 | 2007 |
| Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors C Marty, C Saint-Martin, C Pecquet, S Grosjean, J Saliba, C Mouton, ... Blood 123 (9), 1372-1383, 2014 | 94 | 2014 |
| The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms D Olcaydu, E Rumi, A Harutyunyan, F Passamonti, D Pietra, C Pascutto, ... Haematologica 96 (3), 367-374, 2011 | 85 | 2011 |
Robert KralovicsPrincipal Investigator, Medical University of ViennaVerified email at meduniwien.ac.at
