Fibroblast heterogeneity and immunosuppressive environment in human breast cancer A Costa, Y Kieffer, A Scholer-Dahirel, F Pelon, B Bourachot, M Cardon, ... Cancer cell 33 (3), 463-479. e10, 2018 | 1274 | 2018 |
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch M Lei, W Lu, W Meng, MC Parrini, MJ Eck, BJ Mayer, SC Harrison Cell 102 (3), 387-397, 2000 | 681 | 2000 |
Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells M Reffay, MC Parrini, O Cochet-Escartin, B Ladoux, A Buguin, S Coscoy, ... Nature cell biology 16 (3), 217-223, 2014 | 370 | 2014 |
Oxidative stress promotes myofibroblast differentiation and tumour spreading A Toullec, D Gerald, G Despouy, B Bourachot, M Cardon, S Lefort, ... EMBO molecular medicine 2 (6), 211-230, 2010 | 362 | 2010 |
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1 MC Parrini, M Lei, SC Harrison, BJ Mayer Molecular cell 9 (1), 73-83, 2002 | 302 | 2002 |
Cdc42 is required for PIP2-induced actin polymerization and early development but not for cell viability F Chen, L Ma, MC Parrini, X Mao, M Lopez, C Wu, PW Marks, L Davidson, ... Current biology 10 (13), 758-765, 2000 | 290 | 2000 |
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms F Pelon, B Bourachot, Y Kieffer, I Magagna, F Mermet-Meillon, I Bonnet, ... Nature communications 11 (1), 404, 2020 | 280 | 2020 |
RalB mobilizes the exocyst to drive cell migration C Rossé, A Hatzoglou, MC Parrini, MA White, P Chavrier, J Camonis Molecular and cellular biology, 2006 | 171 | 2006 |
Cell type-specific regulation of RhoA activity during cytokinesis H Yoshizaki, Y Ohba, MC Parrini, NG Dulyaninova, AR Bresnick, ... Journal of Biological Chemistry 279 (43), 44756-44762, 2004 | 147 | 2004 |
Dissecting effects of anti-cancer drugs and cancer-associated fibroblasts by on-chip reconstitution of immunocompetent tumor microenvironments M Nguyen, A De Ninno, A Mencattini, F Mermet-Meillon, G Fornabaio, ... Cell reports 25 (13), 3884-3893. e3, 2018 | 134 | 2018 |
RASSF1A suppresses the invasion and metastatic potential of human non–small cell lung cancer cells by inhibiting YAP activation through the GEF-H1/RhoB pathway F Dubois, M Keller, O Calvayrac, F Soncin, L Hoa, A Hergovich, ... Cancer research 76 (6), 1627-1640, 2016 | 103 | 2016 |
Gradients of Rac1 nanoclusters support spatial patterns of Rac1 signaling A Remorino, S De Beco, F Cayrac, F Di Federico, G Cornilleau, ... Cell reports 21 (7), 1922-1935, 2017 | 92 | 2017 |
SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility MC Parrini, A Sadou-Dubourgnoux, K Aoki, K Kunida, M Biondini, ... Molecular cell 42 (5), 650-661, 2011 | 84 | 2011 |
Automated velocity mapping of migrating cell populations (AVeMap) M Deforet, MC Parrini, L Petitjean, M Biondini, A Buguin, J Camonis, ... Nature methods 9 (11), 1081-1083, 2012 | 64 | 2012 |
Dissecting activation of the PAK1 kinase at protrusions in living cells MC Parrini, J Camonis, M Matsuda, J de Gunzburg Journal of biological chemistry 284 (36), 24133-24143, 2009 | 51 | 2009 |
Spatiotemporal regulation of the Pak1 kinase MC Parrini, M Matsuda, J De Gunzburg Biochemical Society Transactions 33 (4), 646-648, 2005 | 47 | 2005 |
Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments A Mencattini, D Di Giuseppe, MC Comes, P Casti, F Corsi, FR Bertani, ... Scientific reports 10 (1), 7653, 2020 | 45 | 2020 |
RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1 M Biondini, G Duclos, N Meyer-Schaller, P Silberzan, J Camonis, ... Scientific reports 5 (1), 11759, 2015 | 38 | 2015 |
STK 38 kinase acts as XPO 1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes APJ Martin, M Jacquemyn, J Lipecka, C Chhuon, VN Aushev, B Meunier, ... EMBO reports 20 (11), e48150, 2019 | 36 | 2019 |
RalB directly triggers invasion downstream Ras by mobilizing the Wave complex G Zago, I Veith, MK Singh, L Fuhrmann, S De Beco, A Remorino, ... Elife 7, e40474, 2018 | 36 | 2018 |