| Flavonoids suppress Pseudomonas aeruginosa virulence through allosteric inhibition of quorum-sensing receptors JE Paczkowski, S Mukherjee, AR McCready, JP Cong, CJ Aquino, H Kim, ... Journal of Biological Chemistry 292 (10), 4064-4076, 2017 | 273 | 2017 |
| Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system NM Høyland-Kroghsbo, JE Paczkowski, S Mukherjee, J Broniewski, ... Proceedings of the National Academy of Sciences 114 (1), 131-135, 2017 | 257 | 2017 |
| Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis JE Paczkowski, BC Richardson, JC Fromme Trends in Cell Biology 25 (7), 408-416, 2015 | 78 | 2015 |
| Structural determinants driving homoserine lactone ligand selection in the Pseudomonas aeruginosa LasR quorum-sensing receptor AR McCready, JE Paczkowski, BR Henke, BL Bassler Proceedings of the National Academy of Sciences 116 (1), 245-254, 2019 | 74 | 2019 |
| The PqsE-RhlR interaction regulates RhlR DNA binding to control virulence factor production in Pseudomonas aeruginosa KA Simanek, IR Taylor, EK Richael, E Lasek-Nesselquist, BL Bassler, ... Microbiology Spectrum 10 (1), e02108-21, 2022 | 41 | 2022 |
| The exomer cargo adaptor structure reveals a novel GTPase‐binding domain JE Paczkowski, BC Richardson, AM Strassner, JC Fromme The EMBO Journal 31 (21), 4191-4203, 2012 | 41 | 2012 |
| An autoinducer analogue reveals an alternative mode of ligand binding for the LasR quorum-sensing receptor JE Paczkowski, AR McCready, JP Cong, Z Li, PD Jeffrey, CD Smith, ... ACS Chemical Biology 14 (3), 378-389, 2019 | 35 | 2019 |
| Structural basis for membrane binding and remodeling by the exomer secretory vesicle cargo adaptor JE Paczkowski, JC Fromme Developmental Cell 30 (5), 610-624, 2014 | 32 | 2014 |
| Inhibitor mimetic mutations in the Pseudomonas aeruginosa PqsE enzyme reveal a protein–protein interaction with the quorum-sensing receptor RhlR that is vital for virulence … IR Taylor, JE Paczkowski, PD Jeffrey, BR Henke, CD Smith, BL Bassler ACS Chemical Biology 16 (4), 740-752, 2021 | 30 | 2021 |
| Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathway X Huang, OP Duddy, JE Silpe, JE Paczkowski, J Cong, BR Henke, ... Journal of Biological Chemistry 295 (10), 2916-2931, 2020 | 30 | 2020 |
| An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation AR McCready, JE Paczkowski, JP Cong, BL Bassler PLoS Pathogens 15 (6), e1007820, 2019 | 29 | 2019 |
| Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance KA Simanek, JE Paczkowski Microorganisms 10 (6), 1247, 2022 | 16 | 2022 |
| Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation JR Feathers, EK Richael, KA Simanek, JC Fromme, JE Paczkowski Structure 30 (12), 1626-1636. e4, 2022 | 10 | 2022 |
| Analysis of Arf1 GTPase-dependent membrane binding and remodeling using the exomer secretory vesicle cargo adaptor JE Paczkowski, JC Fromme The Golgi Complex: Methods and Protocols, 41-53, 2016 | 6 | 2016 |
| Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine … NR Keegan, NJ Colón Torres, AM Stringer, LI Prager, MW Brockley, ... PLoS Genetics 19 (12), e1010900, 2023 | 2 | 2023 |
| Novel antimicrobial compositions and methods of use B Bassler, N Hoyland-Kroghsbo, J Paczkowski | 1 | 2017 |
| Ligand binding determines proteolytic stability of Vibrio LuxR/HapR quorum sensing transcription factors T Rasal, C Mallery, M Brockley, L Brown, J Paczkowski, J van Kessel bioRxiv, 2024.02. 15.580527, 2024 | | 2024 |
| Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesis KA Simanek, ML Schumacher, CP Mallery, S Shen, L Li, JE Paczkowski Nature Communications 14 (1), 7986, 2023 | | 2023 |
| A New Target for Pseudomonas aeruginosa Drug Discovery B Bassler, I Taylor, J Paczkowski | | 2021 |
| Small Molecule Potentiation of Phage Antimicrobial Activity For Use in Medical, Industrial, Agricultural, and Food Safety Applications N Hoyland-Kroghsbo, J Paczkowski, B Bassler | | 2016 |
