Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space WH Hudson, BR Kossmann, IMS de Vera, SW Chuo, ER Weikum, ... Proceedings of the National Academy of Sciences 113 (2), 326-331, 2016 | 36 | 2016 |
Unexpected allosteric network contributes to LRH-1 co-regulator selectivity PM Musille, BR Kossmann, JA Kohn, I Ivanov, EA Ortlund Journal of Biological Chemistry 291 (3), 1411-1426, 2016 | 29 | 2016 |
Uncovering universal rules governing the selectivity of the archetypal DNA glycosylase TDG T Dodd, C Yan, BR Kossmann, K Martin, I Ivanov Proceedings of the National Academy of Sciences 115 (23), 5974-5979, 2018 | 23 | 2018 |
Secondary interaction interfaces with PCNA control conformational switching of DNA polymerase PolB from polymerization to editing X Xu, C Yan, BR Kossmann, I Ivanov The Journal of Physical Chemistry B 120 (33), 8379-8388, 2016 | 21 | 2016 |
Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft BR Kossmann, M Abdelmalak, S Lopez, G Tender, C Yan, Y Pommier, ... Bioorganic & medicinal chemistry letters 26 (14), 3232-3236, 2016 | 18 | 2016 |
Alkylpurine glycosylase D employs DNA sculpting as a strategy to extrude and excise damaged bases B Kossmann, I Ivanov PLoS Computational Biology 10 (7), e1003704, 2014 | 4 | 2014 |
Computational Investigations of Biomolecular Motions and Interactions in Genomic Maintenance and Regulation BR Kossmann | | 2017 |
Evolving allostery of the 3-ketosteroid family of nuclear receptors B Kossmann, W Hudson, I Ivanov, E Ortlund ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Damage recognition and base extrusion strategies of DNA repair glycosylase enzyme B Kossmann, I Ivanov ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Computational discovery of activating and repressing states for the liver receptor homologue 1 ligand binding domain B Kossmann, P Musille, I Ivanov, E Ortlund ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
An Allosteric Network in LRH‐1 Mediates Phospholipid‐Driven Gene Regulation J Kohn, P Musille, B Kossmann, I Ivanov, E Ortlund The FASEB Journal 29, 715.28, 2015 | | 2015 |
Computational insights for the AlkD base extrusion strategy BR Kossmann, I Ivanov ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013 | | 2013 |