Actionable cytopathogenic host responses of human alveolar type 2 cells to SARS-CoV-2 RM Hekman, AJ Hume, RK Goel, KM Abo, J Huang, BC Blum, RB Werder, ... Molecular cell 80 (6), 1104-1122. e9, 2020 | 111 | 2020 |
Organoids model transcriptional hallmarks of oncogenic KRAS activation in lung epithelial progenitor cells AFM Dost, AL Moye, M Vedaie, LM Tran, E Fung, D Heinze, ... Cell Stem Cell 27 (4), 663-678. e8, 2020 | 97 | 2020 |
SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway DY Chen, N Khan, BJ Close, RK Goel, B Blum, AH Tavares, D Kenney, ... Journal of virology 95 (19), 10.1128/jvi. 00862-21, 2021 | 80* | 2021 |
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease KD Alysandratos, SJ Russo, A Petcherski, EP Taddeo, R Acín-Pérez, ... Cell reports 36 (9), 2021 | 61 | 2021 |
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ... Cell systems 10 (4), 333-350. e14, 2020 | 58 | 2020 |
Single-platform ‘multi-omic’profiling: unified mass spectrometry and computational workflows for integrative proteomics–metabolomics analysis BC Blum, F Mousavi, A Emili Molecular Omics 14 (5), 307-319, 2018 | 46 | 2018 |
A mutation in Hnrnph1 that decreases methamphetamine-induced reinforcement, reward, and dopamine release and increases synaptosomal hnRNP H and mitochondrial proteins QT Ruan, N Yazdani, BC Blum, JA Beierle, W Lin, MA Coelho, EK Fultz, ... Journal of Neuroscience 40 (1), 107-130, 2020 | 42 | 2020 |
Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in … M Deehan, W Lin, B Blum, A Emili, H Frydman MBio 12 (1), 10.1128/mbio. 02205-20, 2021 | 21* | 2021 |
Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo S Kim, N Rabhi, BC Blum, R Hekman, K Wynne, A Emili, S Farmer, ... Archives of toxicology 94, 3087-3103, 2020 | 19 | 2020 |
Loss of G-protein pathway suppressor 2 promotes tumor growth through activation of AKT signaling S Chan, E Smith, Y Gao, J Kwan, BC Blum, AM Tilston-Lunel, I Turcinovic, ... Frontiers in Cell and Developmental Biology 8, 608044, 2021 | 16 | 2021 |
Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection DJ Kenney, AK O’Connell, J Turcinovic, P Montanaro, RM Hekman, ... Cell Reports 39 (3), 2022 | 15 | 2022 |
Proteomic and phosphoproteomic profiling in heart failure with preserved ejection fraction (HFpEF) M Valero-Muñoz, EL Saw, RM Hekman, BC Blum, Z Hourani, H Granzier, ... Frontiers in cardiovascular medicine 9, 966968, 2022 | 12 | 2022 |
Omics Notebook: robust, reproducible and flexible automated multiomics exploratory analysis and reporting BC Blum, A Emili Bioinformatics Advances 1 (1), vbab024, 2021 | 10 | 2021 |
Tangential flow filtration based protein refolding methods BC Blum, C Hollander US Patent 10,183,967B2, 2015 | 6* | 2015 |
Multiomic metabolic enrichment network analysis reveals metabolite–protein physical interaction subnetworks altered in cancer BC Blum, W Lin, ML Lawton, Q Liu, J Kwan, I Turcinovic, R Hekman, P Hu, ... Molecular & Cellular Proteomics 21 (1), 2022 | 5 | 2022 |
Integration of metabolomic and proteomic data to uncover actionable metabolic pathways C Heckendorf, BC Blum, W Lin, ML Lawton, A Emili Cancer Systems and Integrative Biology, 137-148, 2023 | 3 | 2023 |
Platelet proteome analysis reveals an early hyperactive phenotype in SARS-CoV-2-infected humanized ACE2 mice S Subramaniam, RM Hekman, A Jayaraman, AK O’Connell, P Montanaro, ... bioRxiv, 2021.08. 19.457020, 2021 | 3 | 2021 |
High ph protein refolding methods C Hollander, BC Blum US Patent 10,065,987B2, 2016 | 2 | 2016 |
Pilot Study Showing Feasibility of Phosphoproteomic Profiling of Pathway-Level Molecular Alterations in Barrett’s Esophagus J Moore, R Hekman, BC Blum, M Lawton, S Lehoux, M Stachler, ... Genes 13 (7), 1215, 2022 | 1 | 2022 |
Kinetic Exclusion Analysis (KinExA) of avidity enhancement of a multi-valent adnectin binding to clustered receptors on CHO cells LA Schneeweis, SV Hatcher, B Barnhart, TR Glass, L Cheng, B Blum, ... Biophysical Journal 106 (2), 14a-15a, 2014 | 1 | 2014 |