Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10721 | 2021 |
Human Hsp70 disaggregase reverses Parkinson’s-linked α-synuclein amyloid fibrils X Gao, M Carroni, C Nussbaum-Krammer, A Mogk, NB Nillegoda, ... Molecular cell 59 (5), 781-793, 2015 | 390 | 2015 |
Investigating the spreading and toxicity of prion-like proteins using the metazoan model organism C. elegans CI Nussbaum-Krammer, MF Neto, RM Brielmann, JS Pedersen, ... JoVE (Journal of Visualized Experiments), e52321, 2015 | 201 | 2015 |
Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species E Nachman, AS Wentink, K Madiona, L Bousset, T Katsinelos, K Allinson, ... Journal of Biological Chemistry 295 (28), 9676-9690, 2020 | 112 | 2020 |
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments J Kirstein, D Morito, T Kakihana, M Sugihara, A Minnen, MS Hipp, ... The EMBO Journal 34 (18), 2334-2349, 2015 | 88 | 2015 |
Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases CI Nussbaum-Krammer, RI Morimoto Disease models & mechanisms 7 (1), 31-39, 2014 | 79 | 2014 |
Modulation of amyloid states by molecular chaperones A Wentink, C Nussbaum-Krammer, B Bukau Cold Spring Harbor perspectives in biology 11 (7), a033969, 2019 | 77 | 2019 |
The yeast Sup35NM domain propagates as a prion in mammalian cells C Krammer, D Kryndushkin, MH Suhre, E Kremmer, A Hofmann, A Pfeifer, ... Proceedings of the National Academy of Sciences 106 (2), 462-467, 2009 | 76 | 2009 |
Molecular chaperones: a double-edged sword in neurodegenerative diseases J Tittelmeier, E Nachman, C Nussbaum-Krammer Frontiers in aging neuroscience 12, 581374, 2020 | 69 | 2020 |
The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species J Tittelmeier, CA Sandhof, HM Ries, S Druffel‐Augustin, A Mogk, B Bukau, ... The EMBO journal 39 (13), e103954, 2020 | 69 | 2020 |
Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans CI Nussbaum-Krammer, KW Park, L Li, R Melki, RI Morimoto PLoS genetics 9 (3), e1003351, 2013 | 63 | 2013 |
Cell-to-cell propagation of infectious cytosolic protein aggregates JP Hofmann, P Denner, C Nussbaum-Krammer, PH Kuhn, MH Suhre, ... Proceedings of the National Academy of Sciences 110 (15), 5951-5956, 2013 | 57 | 2013 |
Prion-like propagation of cytosolic protein aggregates: insights from cell culture models C Krammer, HM Schätzl, I Vorberg Prion 3 (4), 206-212, 2009 | 57 | 2009 |
NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice P Léger, E Nachman, K Richter, C Tamietti, J Koch, R Burk, S Kummer, ... Nature communications 11 (1), 3281, 2020 | 42 | 2020 |
Mammalian amyloidogenic proteins promote prion nucleation in yeast P Chandramowlishwaran, M Sun, KL Casey, AV Romanyuk, AV Grizel, ... Journal of Biological Chemistry 293 (9), 3436-3450, 2018 | 34 | 2018 |
Therapy in prion diseases: from molecular and cellular biology to therapeutic targets C Krammer, I Vorberg, HM Schatzl, S Gilch Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2009 | 31 | 2009 |
Protein quality control pathways at the crossroad of synucleinopathies EP De Mattos, A Wentink, C Nussbaum-Krammer, C Hansen, S Bergink, ... Journal of Parkinson's disease 10 (2), 369-382, 2020 | 30 | 2020 |
Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading CA Sandhof, SO Hoppe, S Druffel-Augustin, C Gallrein, J Kirstein, ... Autophagy 16 (5), 878-899, 2020 | 27 | 2020 |
Targeting prion proteins in neurodegenerative disease S Gilch, C Krammer, HM Schätzl Expert opinion on biological therapy 8 (7), 923-940, 2008 | 24 | 2008 |
Prion protein/protein interactions: fusion with yeast Sup35p‐NM modulates cytosolic PrP aggregation in mammalian cells C Krammer, MH Suhre, E Kremmer, C Diemer, S Hess, HM Schätzl, ... The FASEB Journal 22 (3), 762-773, 2008 | 20 | 2008 |