SIRT6 promotes DNA repair under stress by activating PARP1 Z Mao, C Hine, X Tian, M Van Meter, M Au, A Vaidya, A Seluanov, ... Science 332 (6036), 1443-1446, 2011 | 905 | 2011 |
High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat X Tian, J Azpurua, C Hine, A Vaidya, M Myakishev-Rempel, J Ablaeva, ... Nature 499 (7458), 346-349, 2013 | 869 | 2013 |
Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 532 | 2020 |
Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 249 | 2023 |
SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ... Cell 177 (3), 622-638. e22, 2019 | 247 | 2019 |
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence Z Mao, X Tian, M Van Meter, Z Ke, V Gorbunova, A Seluanov Proceedings of the National Academy of Sciences 109 (29), 11800-11805, 2012 | 189 | 2012 |
Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism V Gorbunova, C Hine, X Tian, J Ablaeva, AV Gudkov, E Nevo, A Seluanov Proceedings of the National Academy of Sciences 109 (47), 19392-19396, 2012 | 172 | 2012 |
Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age A Vaidya, Z Mao, X Tian, B Spencer, A Seluanov, V Gorbunova PLoS genetics 10 (7), e1004511, 2014 | 118 | 2014 |
INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform X Tian, J Azpurua, Z Ke, A Augereau, ZD Zhang, J Vijg, VN Gladyshev, ... Proceedings of the National Academy of Sciences 112 (4), 1053-1058, 2015 | 115 | 2015 |
Molecular mechanisms determining lifespan in short-and long-lived species X Tian, A Seluanov, V Gorbunova Trends in Endocrinology & Metabolism 28 (10), 722-734, 2017 | 92 | 2017 |
Naked mole rat cells have a stable epigenome that resists iPSC reprogramming L Tan, Z Ke, G Tombline, N Macoretta, K Hayes, X Tian, R Lv, J Ablaeva, ... Stem cell reports 9 (5), 1721-1734, 2017 | 91 | 2017 |
Evolution of telomere maintenance and tumour suppressor mechanisms across mammals X Tian, K Doerig, R Park, A Can Ran Qin, C Hwang, A Neary, M Gilbert, ... Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 88 | 2018 |
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence Y Zhao, A Tyshkovskiy, D Muñoz-Espín, X Tian, M Serrano, ... Proceedings of the National Academy of Sciences 115 (8), 1801-1806, 2018 | 86 | 2018 |
A PARP1–BRG1–SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites Y Chen, H Zhang, Z Xu, H Tang, A Geng, B Cai, T Su, J Shi, C Jiang, ... Nucleic acids research 47 (16), 8563-8580, 2019 | 72 | 2019 |
The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology R Buffenstein, V Amoroso, B Andziak, S Avdieiev, J Azpurua, AJ Barker, ... Biological Reviews 97 (1), 115-140, 2022 | 71 | 2022 |
RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells A Murayama, L Weng, T Date, D Akazawa, X Tian, T Suzuki, T Kato, ... PLoS pathogens 6 (4), e1000885, 2010 | 63 | 2010 |
Radiosensitization by histone H3 demethylase inhibition in diffuse intrinsic pontine glioma H Katagi, N Louis, D Unruh, T Sasaki, X He, A Zhang, Q Ma, A Piunti, ... Clinical cancer research 25 (18), 5572-5583, 2019 | 61 | 2019 |
Beaver and naked mole rat genomes reveal common paths to longevity X Zhou, Q Dou, G Fan, Q Zhang, M Sanderford, A Kaya, J Johnson, ... Cell reports 32 (4), 2020 | 32 | 2020 |
Chemically induced reprogramming to reverse cellular aging JH Yang, CA Petty, T Dixon-McDougall, MV Lopez, A Tyshkovskiy, ... Aging (Albany NY) 15 (13), 5966, 2023 | 30 | 2023 |
Maintenance of genome sequence integrity in long-and short-lived rodent species L Zhang, X Dong, X Tian, M Lee, J Ablaeva, D Firsanov, SG Lee, ... Science Advances 7 (44), eabj3284, 2021 | 30 | 2021 |