| Dual-surface-modified bacteriophage MS2 as an ideal scaffold for a viral capsid-based drug delivery system EW Kovacs, JM Hooker, DW Romanini, PG Holder, KE Berry, MB Francis Bioconjugate chemistry 18 (4), 1140-1147, 2007 | 259 | 2007 |
| Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes PM Drake, AE Albers, J Baker, S Banas, RM Barfield, AS Bhat, ... Bioconjugate chemistry 25 (7), 1331-1341, 2014 | 234 | 2014 |
| Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation R Kudirka, RM Barfield, J McFarland, AE Albers, GW de Hart, PM Drake, ... Chemistry & biology 22 (2), 293-298, 2015 | 79 | 2015 |
| Reconstitution of formylglycine-generating enzyme with copper (II) for aldehyde tag conversion PG Holder, LC Jones, PM Drake, RM Barfield, S Banas, GW de Hart, ... Journal of Biological Chemistry 290 (25), 15730-15745, 2015 | 78 | 2015 |
| Engineering interferons and interleukins for cancer immunotherapy PG Holder, SA Lim, CS Huang, P Sharma, YS Dagdas, B Bulutoglu, ... Advanced drug delivery reviews 182, 114112, 2022 | 69 | 2022 |
| Integration of a Self‐Assembling Protein Scaffold with Water‐Soluble Single‐Walled Carbon Nanotubes PG Holder, MB Francis Angewandte Chemie International Edition 46 (23), 4370-4373, 2007 | 67 | 2007 |
| Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper (II) D York, J Baker, PG Holder, LC Jones, PM Drake, RM Barfield, GT Bleck, ... BMC biotechnology 16, 1-11, 2016 | 53 | 2016 |
| Photo-ribonucleotide reductase β2 by selective cysteine labeling with a radical phototrigger AA Pizano, DA Lutterman, PG Holder, TS Teets, JA Stubbe, DG Nocera Proceedings of the National Academy of Sciences, 2011 | 52 | 2011 |
| Deciphering radical transport in the large subunit of class I ribonucleotide reductase PG Holder, AA Pizano, BL Anderson, JA Stubbe, DG Nocera Journal of the American Chemical Society 134 (2), 1172-1180, 2012 | 51 | 2012 |
| Dramatic Thermal Stability of Virus− Polymer Conjugates in Hydrophobic Solvents PG Holder, DT Finley, N Stephanopoulos, R Walton, DS Clark, ... Langmuir, 2010 | 49 | 2010 |
| Modulation of Y356 Photooxidation in E. coli Class Ia Ribonucleotide Reductase by Y731 Across the α2:β2 Interface AA Pizano, L Olshansky, PG Holder, JA Stubbe, DG Nocera Journal of the American Chemical Society 135 (36), 13250-13253, 2013 | 17 | 2013 |
| Direct interfacial Y 731 oxidation in α 2 by a photoβ 2 subunit of E. coli class Ia ribonucleotide reductase DY Song, AA Pizano, PG Holder, JA Stubbe, DG Nocera Chemical science 6 (8), 4519-4524, 2015 | 12 | 2015 |
| Chemically modified viral capsids as targeted delivery vectors for diagnostic and therapeutic agents MB Francis, JM Hooker, EW Kovacs, DW Romanini, PG Holder, KE Berry | 12 | 2007 |
| High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody–Drug Conjugate Libraries S Yamazoe, JM Hogan, SM West, XA Deng, S Kotapati, X Shao, P Holder, ... Bioconjugate Chemistry 31 (4), 1199-1208, 2020 | 5 | 2020 |
| Complex PK-PD of an engineered IL-15/IL-15Rα–Fc fusion protein in cynomolgus monkeys: QSP modeling of lymphocyte dynamics D Lu, R Yadav, P Holder, E Chiang, S Sanjabi, V Poon, M Bernett, ... European Journal of Pharmaceutical Sciences 186, 106450, 2023 | 3 | 2023 |
| DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody–Drug Conjugate Modality P Sivaprakasam, I McDonald, C Iwuagwu, NS Chowdari, KM Peese, ... ACS Medicinal Chemistry Letters 12 (3), 404-412, 2021 | 3 | 2021 |
| Technologies for Antibody‐Drug Conjugation PG Holder, D Rabuka Biosimilars of Monoclonal Antibodies: A Practical Guide to Manufacturing …, 2016 | 3 | 2016 |
| PD-1 targeted IL-15/IL-15Rα Fc fusion proteins with improved properties J Desjarlais, M Bernett, M Hedvat, R Varma, S Schubbert, C Bonzon, ... US Patent 11,932,675, 2024 | 2 | 2024 |
| Comprehensive UHPLC-and CE-based methods for engineered Cas9 characterization J Camperi, G Console, L Zheng, N Stephens, M Montti, B Roper, M Zheng, ... Talanta 252, 123780, 2023 | 2 | 2023 |
| Antibody comprising a glutamine-containing light chain c-terminal extension, conjugates thereof, and methods and uses P Strop, C Rao-Naik, X Deng, PO Sheppard, PG Holder, S Yamazoe US Patent App. 17/297,796, 2022 | 2 | 2022 |
Matthew FrancisUC BerkeleyVerified email at berkeley.edu
