Structural determinants and mechanism of HIV-1 genome packaging K Lu, X Heng, MF Summers Journal of molecular biology 410 (4), 609-633, 2011 | 339 | 2011 |
NMR detection of structures in the HIV-1 5′-leader RNA that regulate genome packaging K Lu, X Heng, L Garyu, S Monti, EL Garcia, S Kharytonchyk, B Dorjsuren, ... Science 334 (6053), 242-245, 2011 | 298 | 2011 |
Structure of the HIV-1 RNA packaging signal SC Keane, X Heng, K Lu, S Kharytonchyk, V Ramakrishnan, G Carter, ... Science 348 (6237), 917-921, 2015 | 283 | 2015 |
Identification of a minimal region of the HIV-1 5′-leader required for RNA dimerization, NC binding, and packaging X Heng, S Kharytonchyk, EL Garcia, K Lu, SS Divakaruni, C LaCotti, ... Journal of molecular biology 417 (3), 224-239, 2012 | 111 | 2012 |
Structure of the 30 kDa HIV-1 RNA dimerization signal by a hybrid cryo-EM, NMR, and molecular dynamics approach K Zhang, SC Keane, Z Su, RN Irobalieva, M Chen, V Van, CA Sciandra, ... Structure 26 (3), 490-498. e3, 2018 | 64 | 2018 |
Infectivity of SARS-CoV-2: there is something more than D614G? SR Kannan, AN Spratt, TP Quinn, X Heng, CL Lorson, A Sönnerborg, ... Journal of Neuroimmune Pharmacology 15, 574-577, 2020 | 62 | 2020 |
NMR detection of intermolecular interaction sites in the dimeric 5′-leader of the HIV-1 genome SC Keane, V Van, HM Frank, CA Sciandra, S McCowin, J Santos, X Heng, ... Proceedings of the National Academy of Sciences 113 (46), 13033-13038, 2016 | 61 | 2016 |
Database proton NMR chemical shifts for RNA signal assignment and validation S Barton, X Heng, BA Johnson, MF Summers Journal of biomolecular NMR 55, 33-46, 2013 | 59 | 2013 |
DHX9/RHA binding to the PBS-segment of the genomic RNA during HIV-1 assembly bolsters virion infectivity I Boeras, Z Song, A Moran, J Franklin, WC Brown, M Johnson, ... Journal of molecular biology 428 (11), 2418-2429, 2016 | 40 | 2016 |
The basal translation rate of authentic HIV-1 RNA is regulated by 5’UTR nt-pairings at junction of R and U5 I Boeras, B Seufzer, S Brady, A Rendahl, X Heng, K Boris-Lawrie Scientific reports 7 (1), 6902, 2017 | 38 | 2017 |
Feasibility of known RNA polymerase inhibitors as anti-SARS-CoV-2 drugs U Neogi, KJ Hill, AT Ambikan, X Heng, TP Quinn, SN Byrareddy, ... Pathogens 9 (5), 320, 2020 | 28 | 2020 |
HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR G Singh, B Seufzer, Z Song, D Zucko, X Heng, K Boris-Lawrie Proceedings of the National Academy of Sciences 119 (1), e2105153118, 2022 | 27 | 2022 |
Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase PDM Nguyen, J Zheng, TJ Gremminger, L Qiu, D Zhang, S Tuske, ... Nucleic acids research 48 (5), 2709-2722, 2020 | 24 | 2020 |
Virion-associated, host-derived DHX9/RNA helicase A enhances the processivity of HIV-1 reverse transcriptase on genomic RNA S Brady, G Singh, C Bolinger, Z Song, I Boeras, K Weng, B Trent, ... Journal of Biological Chemistry 294 (30), 11473-11485, 2019 | 24 | 2019 |
The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity Z Song, T Gremminger, G Singh, Y Cheng, J Li, L Qiu, J Ji, MJ Lange, ... Nucleic acids research 49 (10), 5925-5942, 2021 | 13 | 2021 |
Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1 T Ku, N Lopresti, M Shirley, M Mori, J Marchant, X Heng, M Botta, ... Bioorganic & medicinal chemistry 27 (13), 2883-2892, 2019 | 12 | 2019 |
Nuclear magnetic resonance study of RNA structures at the 3′-end of the hepatitis C virus genome C Kranawetter, S Brady, L Sun, M Schroeder, SJ Chen, X Heng Biochemistry 56 (37), 4972-4984, 2017 | 11 | 2017 |
Anomalous HIV-1 RNA, how Cap-methylation segregates viral transcripts by form and function K Boris-Lawrie, G Singh, PS Osmer, D Zucko, S Staller, X Heng Viruses 14 (5), 935, 2022 | 9 | 2022 |
An RNA aptamer that shifts the reduction potential of metabolic cofactors JS Samuelian, TJ Gremminger, Z Song, RR Poudyal, J Li, Y Zhou, ... Nature chemical biology 18 (11), 1263-1269, 2022 | 8 | 2022 |
Cellular RNA helicases support early and late events in retroviral replication G Singh, X Heng, K Boris-Lawrie Retrovirus-Cell Interactions, 253-271, 2018 | 6 | 2018 |