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Pei-Chi Yang
Pei-Chi Yang
Project Scientist
Verified email at ucdavis.edu
Title
Cited by
Cited by
Year
A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms
JD Moreno, ZI Zhu, PC Yang, JR Bankston, MT Jeng, C Kang, L Wang, ...
Science translational medicine 3 (98), 98ra83-98ra83, 2011
2282011
Ranolazine for Congenital and Acquired Late INa-Linked Arrhythmias: In Silico Pharmacological Screening
JD Moreno, PC Yang, JR Bankston, E Grandi, DM Bers, RS Kass, ...
Circulation research 113 (7), e50-e61, 2013
942013
Computational approaches to understand cardiac electrophysiology and arrhythmias
BN Roberts, PC Yang, SB Behrens, JD Moreno, CE Clancy
American Journal of Physiology-Heart and Circulatory Physiology 303 (7 …, 2012
862012
Role of membrane microdomains in compartmentation of cAMP signaling
SR Agarwal, PC Yang, M Rice, CA Singer, VO Nikolaev, MJ Lohse, ...
PloS one 9 (4), e95835, 2014
832014
NFAT and NFκB activation in T lymphocytes: a model of differential activation of gene expression
WG Fisher, PC Yang, RK Medikonduri, MS Jafri
Annals of biomedical engineering 34, 1712-1728, 2006
782006
A novel heterozygous mutation in cardiac calsequestrin causes autosomal dominant catecholaminergic polymorphic ventricular tachycardia
B Gray, RD Bagnall, L Lam, J Ingles, C Turner, E Haan, A Davis, PC Yang, ...
Heart Rhythm 13 (8), 1652-1660, 2016
742016
Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study
PC Yang, J Kurokawa, T Furukawa, CE Clancy
PLoS computational biology 6 (1), e1000658, 2010
722010
A computational pipeline to predict cardiotoxicity: from the atom to the rhythm
PC Yang, KR DeMarco, P Aghasafari, MT Jeng, JRD Dawson, S Bekker, ...
Circulation research 126 (8), 947-964, 2020
652020
In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome
L Romero, B Trenor, PC Yang, J Saiz, CE Clancy
Journal of molecular and cellular cardiology 72, 126-137, 2014
642014
In silico prediction of sex-based differences in human susceptibility to cardiac ventricular tachyarrhythmias
PC Yang, CE Clancy
Frontiers in physiology 3, 33341, 2012
642012
Effects of sex hormones on cardiac repolarization
PC Yang, CE Clancy
Journal of cardiovascular pharmacology 56 (2), 123-129, 2010
562010
A computational modeling and simulation approach to investigate mechanisms of subcellular cAMP compartmentation
PC Yang, BW Boras, MT Jeng, SS Docken, TJ Lewis, AD McCulloch, ...
PLoS computational biology 12 (7), e1005005, 2016
482016
A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal‐induced arrhythmias
PC Yang, LL Perissinotti, F López‐Redondo, Y Wang, KR DeMarco, ...
The Journal of physiology 595 (14), 4695-4723, 2017
442017
Compartmentalized cAMP signaling associated with lipid raft and non-raft membrane domains in adult ventricular myocytes
SR Agarwal, J Gratwohl, M Cozad, PC Yang, CE Clancy, RD Harvey
Frontiers in pharmacology 9, 343518, 2018
402018
In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia
PC Yang, JD Moreno, CY Miyake, SB Vaughn‐Behrens, MT Jeng, ...
The Journal of physiology 594 (3), 567-593, 2016
392016
When Does the IC50 Accurately Assess the Blocking Potency of a Drug?
J Gomis-Tena, BM Brown, J Cano, B Trenor, PC Yang, J Saiz, CE Clancy, ...
Journal of chemical information and modeling 60 (3), 1779-1790, 2020
382020
Determinants of isoform-specific gating kinetics of hERG1 channel: combined experimental and simulation study
LL Perissinotti, PM De Biase, J Guo, PC Yang, MC Lee, CE Clancy, ...
Frontiers in physiology 9, 306853, 2018
332018
Sex‐specific classification of drug‐induced torsade de pointes susceptibility using cardiac simulations and machine learning
A Fogli Iseppe, H Ni, S Zhu, X Zhang, R Coppini, PC Yang, U Srivatsa, ...
Clinical Pharmacology & Therapeutics 110 (2), 380-391, 2021
282021
A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current
PC Yang, Y Song, WR Giles, B Horvath, Y Chen‐Izu, L Belardinelli, ...
The Journal of physiology 593 (6), 1429-1442, 2015
282015
A computational model predicts adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current
PC Yang, N El-Bizri, L Romero, WR Giles, S Rajamani, L Belardinelli, ...
Journal of molecular and cellular cardiology 99, 151-161, 2016
222016
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