| The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Y Zhan, Y Chen, Q Zhang, J Zhuang, M Tian, H Chen, L Zhang, H Zhang, ... Nature chemical biology 8 (11), 897-904, 2012 | 179 | 2012 |
| A quick route to multiple highly potent SARS‐CoV‐2 main protease inhibitors KS Yang, XR Ma, Y Ma, YR Alugubelli, DA Scott, EC Vatansever, ... ChemMedChem 16 (6), 942-948, 2021 | 103 | 2021 |
| Bepridil is potent against SARS-CoV-2 in vitro EC Vatansever, KS Yang, AK Drelich, KC Kratch, CC Cho, KR Kempaiah, ... Proceedings of the National Academy of Sciences 118 (10), e2012201118, 2021 | 96 | 2021 |
| Evolutionary and structural insights about potential SARS-CoV-2 evasion of nirmatrelvir KS Yang, SZ Leeuwon, S Xu, WR Liu Journal of medicinal chemistry 65 (13), 8686-8698, 2022 | 68 | 2022 |
| Crystal structure of the ERp44-peroxiredoxin 4 complex reveals the molecular mechanisms of thiol-mediated protein retention K Yang, DF Li, J Liang, R Sitia, C Wang, X Wang Structure 24 (10), 1755-1765, 2016 | 40 | 2016 |
| Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes S Xu, Y Liu, K Yang, H Wang, A Shergalis, A Kyani, A Bankhead III, ... Theranostics 9 (8), 2282, 2019 | 38 | 2019 |
| Evaluation of SARS-CoV-2 main protease inhibitors using a novel cell-based assay W Cao, CCD Cho, ZZ Geng, N Shaabani, XR Ma, EC Vatansever, ... ACS central science 8 (2), 192-204, 2022 | 35 | 2022 |
| A novel reaction of peroxiredoxin 4 towards substrates in oxidative protein folding L Zhu, K Yang, X Wang, X Wang, C Wang PloS one 9 (8), e105529, 2014 | 34 | 2014 |
| Drug repurposing for the SARS‐CoV‐2 papain‐like protease CC Cho, SG Li, TJ Lalonde, KS Yang, G Yu, Y Qiao, S Xu, W Ray Liu ChemMedChem 17 (1), e202100455, 2022 | 33 | 2022 |
| Targeting the SARS-CoV-2 main protease to repurpose drugs for COVID-19 EC Vatansever, K Yang, KC Kratch, A Drelich, CC Cho, DM Mellot, S Xu, ... BioRxiv, 2020.05. 23.112235, 2020 | 32 | 2020 |
| A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... European Journal of Medicinal Chemistry 240, 114570, 2022 | 31 | 2022 |
| A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... European Journal of Medicinal Chemistry 240, 114596, 2022 | 26 | 2022 |
| Self-masked aldehyde inhibitors: a novel strategy for inhibiting cysteine proteases L Li, BC Chenna, KS Yang, TR Cole, ZT Goodall, M Giardini, ... Journal of medicinal chemistry 64 (15), 11267-11287, 2021 | 24 | 2021 |
| Discovery of selective small-molecule inhibitors for the ENL YEATS domain XR Ma, L Xu, S Xu, BJ Klein, H Wang, S Das, K Li, KS Yang, S Sohail, ... Journal of medicinal chemistry 64 (15), 10997-11013, 2021 | 23 | 2021 |
| Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity H Li, K Yang, W Wang, Y Niu, J Li, Y Dong, Y Liu, C Wang, L Wang, ... Journal of Biological Chemistry 293 (4), 1192-1202, 2018 | 12 | 2018 |
| An enhanced hybrid screening approach to identify potent inhibitors for the SARS-CoV-2 main protease from the NCI compound library SG Li, KS Yang, LR Blankenship, CCD Cho, S Xu, H Wang, WR Liu Frontiers in Chemistry 10, 816576, 2022 | 9 | 2022 |
| Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease KS Yang, STA Kuo, LR Blankenship, ZZ Geng, SG Li, DH Russell, X Yan, ... Current Research in Chemical Biology 2, 100025, 2022 | 9 | 2022 |
| A systematic survey of reversibly covalent dipeptidyl inhibitors of the SARS-CoV-2 main protease ZZ Geng, S Atla, N Shaabani, V Vulupala, KS Yang, YR Alugubelli, ... Journal of Medicinal Chemistry 66 (16), 11040-11055, 2023 | 8 | 2023 |
| A Novel Y-shaped, S–O–N–O–S-bridged cross-link between three residues C22, C44, and K61 is frequently observed in the SARS-CoV-2 main Protease KS Yang, LR Blankenship, STA Kuo, YJ Sheng, P Li, CA Fierke, ... ACS Chemical Biology 18 (3), 449-455, 2023 | 7 | 2023 |
| Cellular activities of SARS-CoV-2 main protease inhibitors reveal their unique characteristics W Cao, CCD Cho, ZZ Geng, XR Ma, R Allen, N Shaabani, EC Vatansever, ... bioRxiv, 2021.06. 08.447613, 2021 | 7 | 2021 |
Wenshe R. LiuHarry E. Bovay, Jr. Endowed Chair in Chemistry and Professor, Texas A&M UniversityVerified email at chem.tamu.edu
