mTORC1 as the main gateway to autophagy Y Rabanal-Ruiz, EG Otten, VI Korolchuk Essays in biochemistry 61 (6), 565-584, 2017 | 481 | 2017 |
Autophagy, lipophagy and lysosomal lipid storage disorders C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 256 | 2016 |
The cargo receptor NDP52 initiates selective autophagy by recruiting the ULK complex to cytosol-invading bacteria BJ Ravenhill, KB Boyle, N von Muhlinen, CJ Ellison, GR Masson, ... Molecular cell 74 (2), 320-329. e6, 2019 | 246 | 2019 |
Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection EG Otten, E Werner, A Crespillo-Casado, KB Boyle, V Dharamdasani, ... Nature 594 (7861), 111-116, 2021 | 216 | 2021 |
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ... Elife 5, e11058, 2016 | 206 | 2016 |
Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions P Dalle Pezze, G Nelson, EG Otten, VI Korolchuk, TBL Kirkwood, ... PLoS computational biology 10 (8), e1003728, 2014 | 169 | 2014 |
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis B Carroll, EG Otten, D Manni, R Stefanatos, FM Menzies, GR Smith, ... Nature communications 9 (1), 256, 2018 | 145 | 2018 |
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ... Autophagy 12 (10), 1917-1930, 2016 | 145 | 2016 |
An induced pluripotent stem cell patient specific model of complement factor H (Y402H) polymorphism displays characteristic features of age-related macular degeneration and … D Hallam, J Collin, S Bojic, V Chichagova, A Buskin, Y Xu, L Lafage, ... Stem Cells 35 (11), 2305-2320, 2017 | 67 | 2017 |
Autophagy promotes cell survival by maintaining NAD levels T Kataura, L Sedlackova, EG Otten, R Kumari, D Shapira, F Scialo, ... Developmental cell 57 (22), 2584-2598. e11, 2022 | 37 | 2022 |
PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder A Brown, S Patel, C Ward, A Lorenz, M Ortiz, A DuRoss, F Wieghardt, ... Scientific reports 6 (1), 31750, 2016 | 37 | 2016 |
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy T Kataura, EG Otten, Y Rabanal‐Ruiz, E Adriaenssens, F Urselli, F Scialo, ... The EMBO Journal 42 (5), e111372, 2023 | 20 | 2023 |
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ... Cell reports 42 (5), 2023 | 12 | 2023 |
Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions EG Otten, R Stefanatos, B Carroll, VI Korolchuk Cell stress 2 (4), 91, 2018 | 7 | 2018 |
Mitochondrial degradation, autophagy and neurodegenerative disease EG Otten, D Manni, VI Korolchuk Mitochondrial Dysfunction in Neurodegenerative Disorders, 255-278, 2016 | 7 | 2016 |
Autophagy promotes cell and organismal survival by maintaining NAD (H) pools L Sedlackova, EG Otten, F Scialo, D Shapira, T Kataura, B Carroll, ... Biorxiv, 2020.01. 31.928424, 2020 | 6 | 2020 |
An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure D Hallam, J Collin, S Bojic, V Chichagova, A Buskin, Y Xu, L Lafage, ... Stem Cells 35 (11), 2017 | 4 | 2017 |
Korolchuk VI. Autophagy, lipophagy and lysosomal lipid storage disorders C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ... Biochim. Biophys. Acta 1861, 269-284, 2016 | 3 | 2016 |
The evolution of selective autophagy as a mechanism of oxidative stress response: the evolutionarily acquired ability of selective autophagy receptors to respond to oxidative … J Ratliffe, T Kataura, EG Otten, VI Korolchuk Bioessays 45 (11), 2300076, 2023 | 2 | 2023 |
Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ... Elife 9, e65744, 2020 | 1 | 2020 |