Follow
Elsje Gesina (Gisela) Otten
Elsje Gesina (Gisela) Otten
Postdoc at the MRC Laboratory of Molecular Biology ( MRC LMB) in Cambridge
Verified email at mrc-lmb.cam.ac.uk
Title
Cited by
Cited by
Year
mTORC1 as the main gateway to autophagy
Y Rabanal-Ruiz, EG Otten, VI Korolchuk
Essays in biochemistry 61 (6), 565-584, 2017
4812017
Autophagy, lipophagy and lysosomal lipid storage disorders
C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016
2562016
The cargo receptor NDP52 initiates selective autophagy by recruiting the ULK complex to cytosol-invading bacteria
BJ Ravenhill, KB Boyle, N von Muhlinen, CJ Ellison, GR Masson, ...
Molecular cell 74 (2), 320-329. e6, 2019
2462019
Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection
EG Otten, E Werner, A Crespillo-Casado, KB Boyle, V Dharamdasani, ...
Nature 594 (7861), 111-116, 2021
2162021
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ...
Elife 5, e11058, 2016
2062016
Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions
P Dalle Pezze, G Nelson, EG Otten, VI Korolchuk, TBL Kirkwood, ...
PLoS computational biology 10 (8), e1003728, 2014
1692014
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis
B Carroll, EG Otten, D Manni, R Stefanatos, FM Menzies, GR Smith, ...
Nature communications 9 (1), 256, 2018
1452018
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair
G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ...
Autophagy 12 (10), 1917-1930, 2016
1452016
An induced pluripotent stem cell patient specific model of complement factor H (Y402H) polymorphism displays characteristic features of age-related macular degeneration and …
D Hallam, J Collin, S Bojic, V Chichagova, A Buskin, Y Xu, L Lafage, ...
Stem Cells 35 (11), 2305-2320, 2017
672017
Autophagy promotes cell survival by maintaining NAD levels
T Kataura, L Sedlackova, EG Otten, R Kumari, D Shapira, F Scialo, ...
Developmental cell 57 (22), 2584-2598. e11, 2022
372022
PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder
A Brown, S Patel, C Ward, A Lorenz, M Ortiz, A DuRoss, F Wieghardt, ...
Scientific reports 6 (1), 31750, 2016
372016
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
T Kataura, EG Otten, Y Rabanal‐Ruiz, E Adriaenssens, F Urselli, F Scialo, ...
The EMBO Journal 42 (5), e111372, 2023
202023
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ...
Cell reports 42 (5), 2023
122023
Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions
EG Otten, R Stefanatos, B Carroll, VI Korolchuk
Cell stress 2 (4), 91, 2018
72018
Mitochondrial degradation, autophagy and neurodegenerative disease
EG Otten, D Manni, VI Korolchuk
Mitochondrial Dysfunction in Neurodegenerative Disorders, 255-278, 2016
72016
Autophagy promotes cell and organismal survival by maintaining NAD (H) pools
L Sedlackova, EG Otten, F Scialo, D Shapira, T Kataura, B Carroll, ...
Biorxiv, 2020.01. 31.928424, 2020
62020
An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure
D Hallam, J Collin, S Bojic, V Chichagova, A Buskin, Y Xu, L Lafage, ...
Stem Cells 35 (11), 2017
42017
Korolchuk VI. Autophagy, lipophagy and lysosomal lipid storage disorders
C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ...
Biochim. Biophys. Acta 1861, 269-284, 2016
32016
The evolution of selective autophagy as a mechanism of oxidative stress response: the evolutionarily acquired ability of selective autophagy receptors to respond to oxidative …
J Ratliffe, T Kataura, EG Otten, VI Korolchuk
Bioessays 45 (11), 2300076, 2023
22023
Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
B Carroll, D Maetzel, ODK Maddocks, G Otten, M Ratcliff, GR Smith, ...
Elife 9, e65744, 2020
12020
The system can't perform the operation now. Try again later.
Articles 1–20