| Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death X Wen, W Tan, T Westergard, K Krishnamurthy, ... Neuron 84 (6), 1213-1225, 2014 | 556 | 2014 |
| Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha A Kia, K McAvoy, K Krishnamurthy, D Trotti, P Pasinelli Glia 23298 (doi: 10.1002/glia.23298.), doi: 10.1002/glia.23298., 2018 | 102 | 2018 |
| Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity JG Daigle, K Krishnamurthy, N Ramesh, I Casci, J Monaghan, K McAvoy, ... Acta neuropathologica 131, 605-620, 2016 | 63 | 2016 |
| Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ... EMBO molecular medicine 12 (5), e10722, 2020 | 45 | 2020 |
| Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization I Casci, K Krishnamurthy, S Kour, V Tripathy, N Ramesh, EN Anderson, ... Nature Communications 10 (1), 5583, 2019 | 33 | 2019 |
| AMPA induced Ca2+ influx in motor neurons occurs through voltage gated Ca2+ channel and Ca2+ permeable AMPA receptor DC Joshi, M Singh, K Krishnamurthy, PG Joshi, NB Joshi Neurochemistry international 59 (6), 913-921, 2011 | 26 | 2011 |
| AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury BA Charsar, MA Brinton, K Locke, AY Chen, B Ghosh, MW Urban, ... The FASEB Journal 33 (12), 13775, 2019 | 22 | 2019 |
| A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ... Scientific Reports 12 (1), 5644, 2022 | 13 | 2022 |
| Synaptic dysfunction in ALS/FTD-Therapeutic strategies and novel biomarkers K Krishnamurthy, P Pasinelli Journal of neuroscience research 99 (6), 1499, 2021 | 9 | 2021 |
| Real-time fluorescent measurement of synaptic functions in models of amyotrophic lateral sclerosis K Krishnamurthy, D Trotti, P Pasinelli, B Jensen JoVE (Journal of Visualized Experiments), e62813, 2021 | 6 | 2021 |
| C9orf72 poly (PR) mediated neurodegeneration is associated with nucleolar stress ME Cicardi, JH Hallgren, D Mawrie, K Krishnamurthy, SS Markandaiah, ... Iscience 26 (9), 2023 | 4 | 2023 |
| Depalmitoylation preferentially downregulates AMPA induced Ca2+ signaling and neurotoxicity in motor neurons K Krishnamurthy, B Mehta, M Singh, BP Tewari, PG Joshi, NB Joshi Brain research 1529, 143-153, 2013 | 4 | 2013 |
| Kapβ2 is a modifier of the C9orf72-linked glycine-arginine dipeptide neurotoxicity ME Cicardi, V Kankate, S Sriramoji, K Krishnamurthy, SS Markandaiah, ... bioRxiv, 2022.09. 30.510384, 2022 | 1 | 2022 |
| IL-11 induces NLRP3 inflammasome activation, inflammatory cell migration to the CNS and neurotoxicity (P7-6.017) K Krishnamurthy, M Seyedsadr, P Pasinelli, S Markovic-Plese Neurology 102 (17_supplement_1), 6653, 2024 | | 2024 |
| Emerging perspectives of synaptic biomarkers in ALS and FTD K Krishnamurthy, RK Pradhan Frontiers in Molecular Neuroscience 16, 2023 | | 2023 |
| Aberrant expression of the axon guidance cue netrin-1 by SOD1-ALS astrocytes contributes to motor neuron degeneration. K Krishnamurthy, S Markandaiah, M Cicardi, B Ghosh, X Wen, K McAvoy, ... GLIA 69, E194-E194, 2021 | | 2021 |
| Cultured cortical neurons transfected with genetically encoded calcium indicator GCaMP6m shows repetitive calcium spikes indicative of neuronal hyperexcitability induced by … K Krishnamurthy, H Aaron, D Trotti, P Pasinelli https://www.faseb.org/Publications-and-Resources/BioArt/About-BioArt/2020 …, 2020 | | 2020 |
| Fluorescence Imaging of Astrocytes Expressing a Toxic Protein, SOD1 K Krishnamurthy, SM Markandaiah, D Trotti, P Pasinelli https://faseb.org/Publications-and-Resources/BioArt/Past-Winners/2019-BioArt …, 2019 | | 2019 |
Davide TrottiProfessor of Neuroscience, Thomas Jefferson UniversityVerified email at jefferson.edu
