| Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo AC Nguyen, WR Burack, JL Stock, R Kortum, OV Chaika, M Afkarian, ... Molecular and cellular biology 22 (9), 3035-3045, 2002 | 346 | 2002 |
| Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP SA Matheny, C Chen, RL Kortum, GL Razidlo, RE Lewis, MA White Nature 427 (6971), 256-260, 2004 | 273 | 2004 |
| The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells RL Kortum, RE Lewis Molecular and cellular biology, 2004 | 181 | 2004 |
| KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity DL Costanzo-Garvey, PT Pfluger, MK Dougherty, JL Stock, M Boehm, ... Cell metabolism 10 (5), 366-378, 2009 | 158 | 2009 |
| The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters L Balagopalan, RL Kortum, NP Coussens, VA Barr, LE Samelson Journal of Biological Chemistry 290 (44), 26422-26429, 2015 | 132 | 2015 |
| Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells RL Kortum, AK Rouquette-Jazdanian, LE Samelson Trends in immunology 34 (6), 259-268, 2013 | 106 | 2013 |
| Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation GL Razidlo, RL Kortum, JL Haferbier, RE Lewis Journal of Biological Chemistry 279 (46), 47808-47814, 2004 | 91 | 2004 |
| The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis RL Kortum, DL Costanzo, J Haferbier, SJ Schreiner, GL Razidlo, MH Wu, ... Molecular and cellular biology 25 (17), 7592-7604, 2005 | 89 | 2005 |
| Distinct binding preferences between Ras and Raf family members and the impact on oncogenic Ras signaling EM Terrell, DE Durrant, DA Ritt, NE Sealover, E Sheffels, ... Molecular cell 76 (6), 872-884. e5, 2019 | 86 | 2019 |
| Targeted Sos1 deletion reveals its critical role in early T-cell development RL Kortum, CL Sommers, CP Alexander, JM Pinski, W Li, A Grinberg, ... Proceedings of the National Academy of Sciences 108 (30), 12407-12412, 2011 | 73 | 2011 |
| Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival FC Baltanás, M Pérez-Andrés, A Ginel-Picardo, D Diaz, D Jimeno, ... Molecular and cellular biology 33 (22), 4562-4578, 2013 | 59 | 2013 |
| The Molecular Scaffold Kinase Suppressor of Ras 1 Is a Modifier of RasV12-Induced and Replicative Senescence RL Kortum, HJ Johnson, DL Costanzo, DJ Volle, GL Razidlo, AM Fusello, ... Molecular and cellular biology 26 (6), 2202-2214, 2006 | 58 | 2006 |
| Deconstructing Ras signaling in the thymus RL Kortum, CL Sommers, JM Pinski, CP Alexander, RK Merrill, W Li, ... Molecular and cellular biology 32 (14), 2748-2759, 2012 | 57 | 2012 |
| Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer PL Theard, E Sheffels, NE Sealover, AJ Linke, DJ Pratico, RL Kortum Elife 9, e58204, 2020 | 55 | 2020 |
| The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo RL Kortum, L Balagopalan, CP Alexander, J Garcia, JM Pinski, RK Merrill, ... Science signaling 6 (301), ra99-ra99, 2013 | 52 | 2013 |
| Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic Ras-dependent anchorage-independent growth KW Fisher, B Das, RL Kortum, OV Chaika, RE Lewis Molecular and cellular biology, 2011 | 52 | 2011 |
| Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling L Balagopalan, VA Barr, RL Kortum, AK Park, LE Samelson The Journal of Immunology 190 (8), 3849-3853, 2013 | 48 | 2013 |
| Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation E Sheffels, NE Sealover, C Wang, DH Kim, IA Vazirani, E Lee, E M. Terrell, ... Science signaling 11 (546), eaar8371, 2018 | 43 | 2018 |
| LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation AK Rouquette-Jazdanian, CL Sommers, RL Kortum, DK Morrison, ... Molecular cell 48 (2), 298-312, 2012 | 38 | 2012 |
| The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid–liquid phase separation I Owen, D Yee, H Wyne, TM Perdikari, V Johnson, J Smyth, R Kortum, ... Journal of cell science 134 (17), jcs258578, 2021 | 37 | 2021 |
