| The translation inhibitor rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA S Iwasaki, W Iwasaki, M Takahashi, A Sakamoto, C Watanabe, Y Shichino, ... Molecular cell 73 (4), 738-748. e9, 2019 | 155 | 2019 |
| Tunneling spectroscopy of superconducting S Kashiwaya, T Ito, K Oka, S Ueno, H Takashima, M Koyanagi, Y Tanaka, ... Physical Review B 57 (14), 8680, 1998 | 151 | 1998 |
| Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis M Kato, T Ito, G Wagner, CC Richardson, T Ellenberger Molecular cell 11 (5), 1349-1360, 2003 | 125 | 2003 |
| Crystal structure of eukaryotic translation initiation factor 2B K Kashiwagi, M Takahashi, M Nishimoto, TB Hiyama, T Higo, T Umehara, ... Nature 531 (7592), 122-125, 2016 | 120 | 2016 |
| ISRIB blunts the integrated stress response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B AF Zyryanova, K Kashiwagi, C Rato, HP Harding, A Crespillo-Casado, ... Molecular cell 81 (1), 88-103. e6, 2021 | 110 | 2021 |
| Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation S Goto-Ito, T Ito, M Kuratani, Y Bessho, S Yokoyama Nature structural & molecular biology 16 (10), 1109-1115, 2009 | 110 | 2009 |
| Structural basis for eIF2B inhibition in integrated stress response K Kashiwagi, T Yokoyama, M Nishimoto, M Takahashi, A Sakamoto, ... Science 364 (6439), 495-499, 2019 | 109 | 2019 |
| Solution structure of human initiation factor eIF2α reveals homology to the elongation factor eEF1B T Ito, A Marintchev, G Wagner Structure 12 (9), 1693-1704, 2004 | 97 | 2004 |
| Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma. K Fujikawa, K Shiraki, K Sugimoto, T Ito, T Yamanaka, K Takase, ... Anticancer research 20 (3B), 1927-1932, 2000 | 86 | 2000 |
| Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms K Hanawa-Suetsugu, M Kukimoto-Niino, C Mishima-Tsumagari, ... Proceedings of the National Academy of Sciences 109 (9), 3305-3310, 2012 | 76 | 2012 |
| Methyl transfer by substrate signaling from a knotted protein fold T Christian, R Sakaguchi, AP Perlinska, G Lahoud, T Ito, EA Taylor, ... Nature structural & molecular biology 23 (10), 941-948, 2016 | 75 | 2016 |
| Crystal structure of archaeal tRNA(m1G37)methyltransferase aTrm5 S Goto‐Ito, T Ito, R Ishii, Y Muto, Y Bessho, S Yokoyama Proteins: Structure, Function, and Bioinformatics 72 (4), 1274-1289, 2008 | 73 | 2008 |
| Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions T Ito, S Yokoyama Nature 467 (7315), 612-616, 2010 | 67 | 2010 |
| Compression mechanism and amorphization of portlandite, Ca(OH)2: structural refinement under pressure T Nagai, T Ito, T Hattori, T Yamanaka Physics and Chemistry of Minerals 27, 462-466, 2000 | 59 | 2000 |
| Structural basis for methyl-donor–dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD T Ito, I Masuda, K Yoshida, S Goto-Ito, S Sekine, SW Suh, YM Hou, ... Proceedings of the National Academy of Sciences 112 (31), E4197-E4205, 2015 | 58 | 2015 |
| Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis S Goto-Ito, R Ishii, T Ito, R Shibata, E Fusatomi, S Sekine, Y Bessho, ... Acta Crystallographica Section D: Biological Crystallography 63 (10), 1059-1068, 2007 | 57 | 2007 |
| Solution structures of the first and second RNA‐binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF65) T Ito, Y Muto, MR Green, S Yokoyama The EMBO journal, 1999 | 51 | 1999 |
| HCV IRES captures an actively translating 80S ribosome T Yokoyama, K Machida, W Iwasaki, T Shigeta, M Nishimoto, ... Molecular cell 74 (6), 1205-1214. e8, 2019 | 48 | 2019 |
| Demonstration by reverse transcription-polymerase chain reaction of multiple cytokine mRNA expression in bovine alveolar macrophages and peripheral blood mononuclear cells T Ito, M Kodama Research in veterinary science 60 (1), 94-96, 1996 | 48 | 1996 |
| Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance V Gelev, H Aktas, A Marintchev, T Ito, D Frueh, M Hemond, D Rovnyak, ... Journal of molecular biology 364 (3), 352-363, 2006 | 47 | 2006 |
