| The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance A Villagra, F Cheng, HW Wang, I Suarez, M Glozak, M Maurin, D Nguyen, ... Nature immunology 10 (1), 92-100, 2009 | 502 | 2009 |
| HDAC inhibition upregulates PD-1 ligands in melanoma and augments immunotherapy with PD-1 blockade DM Woods, AL Sodré, A Villagra, A Sarnaik, EM Sotomayor, J Weber Cancer immunology research 3 (12), 1375-1385, 2015 | 410 | 2015 |
| Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer JI Youn, V Kumar, M Collazo, Y Nefedova, T Condamine, P Cheng, ... Nature immunology 14 (3), 211-220, 2013 | 373 | 2013 |
| Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity J Sierra, A Villagra, R Paredes, F Cruzat, S Gutierrez, A Javed, ... Molecular and cellular biology 23 (9), 3339-3351, 2003 | 241 | 2003 |
| Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth JA Bergman, K Woan, P Perez-Villarroel, A Villagra, EM Sotomayor, ... Journal of medicinal chemistry 55 (22), 9891-9899, 2012 | 236 | 2012 |
| Histone deacetylases and the immunological network: implications in cancer and inflammation A Villagra, EM Sotomayor, E Seto Oncogene 29 (2), 157-173, 2010 | 230 | 2010 |
| Epigenetic therapy for ovarian cancer: promise and progress S Moufarrij, M Dandapani, E Arthofer, S Gomez, A Srivastava, ... Clinical epigenetics 11, 1-11, 2019 | 217 | 2019 |
| Bone-Specific Transcription Factor Runx2 Interacts with the 1α,25-Dihydroxyvitamin D3 Receptor To Up-Regulate Rat Osteocalcin Gene Expression in Osteoblastic … R Paredes, G Arriagada, F Cruzat, A Villagra, J Olate, K Zaidi, ... Molecular and cellular biology 24 (20), 8847-8861, 2004 | 153 | 2004 |
| Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of … T Knox, E Sahakian, D Banik, M Hadley, E Palmer, S Noonepalle, J Kim, ... Scientific reports 9 (1), 6136, 2019 | 145 | 2019 |
| Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation KV Woan, M Lienlaf, P Perez-Villaroel, C Lee, F Cheng, T Knox, ... Molecular oncology 9 (7), 1447-1457, 2015 | 145 | 2015 |
| Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells F Cheng, M Lienlaf, P Perez-Villarroel, HW Wang, C Lee, K Woan, ... Molecular immunology 60 (1), 44-53, 2014 | 144 | 2014 |
| Essential role of HDAC6 in the regulation of PD-L1 in melanoma M Lienlaf, P Perez-Villarroel, T Knox, M Pabon, E Sahakian, J Powers, ... Molecular oncology 10 (5), 735-750, 2016 | 142 | 2016 |
| The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions Z Yuan, A Villagra, L Peng, D Coppola, M Glozak, EM Sotomayor, J Chen, ... Molecular and cellular biology 30 (12), 3004-3015, 2010 | 136 | 2010 |
| The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity DM Woods, K Woan, F Cheng, H Wang, P Perez-Villarroel, C Lee, ... Melanoma research 23 (5), 341-348, 2013 | 130 | 2013 |
| Reduced CpG methylation is associated with transcriptional activation of the bone‐specific rat osteocalcin gene in osteoblasts A Villagra, J Gutiérrez, R Paredes, J Sierra, M Puchi, M Imschenetzky, ... Journal of cellular biochemistry 85 (1), 112-122, 2002 | 125 | 2002 |
| Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function E Sahakian, JJ Powers, J Chen, SL Deng, F Cheng, A Distler, DM Woods, ... Molecular immunology 63 (2), 579-585, 2015 | 123 | 2015 |
| Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation H Lee, N Sengupta, A Villagra, N Rezai-Zadeh, E Seto Molecular and cellular biology 26 (14), 5259-5269, 2006 | 119 | 2006 |
| Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma DN Yarde, V Oliveira, L Mathews, X Wang, A Villagra, D Boulware, ... Cancer research 69 (24), 9367-9375, 2009 | 118 | 2009 |
| A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs F Cheng, M Lienlaf, HW Wang, P Perez-Villarroel, C Lee, K Woan, ... The Journal of Immunology 193 (6), 2850-2862, 2014 | 110 | 2014 |
| Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy–mediated metastatic melanoma phenotype KHT Paraiso, MD Thakur, B Fang, JM Koomen, IV Fedorenko, JK John, ... Cancer discovery 5 (3), 264-273, 2015 | 108 | 2015 |
Eva Sahakian, Ph.DSenior Research Scientist Moffitt cancer center; Assistant Professor USF Morsani School of MedicineVerified email at moffitt.org
