Structure and function of the histone chaperone FACT–Resolving FACTual issues K Gurova, HW Chang, ME Valieva, P Sandlesh, VM Studitsky Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (9), 892-904, 2018 | 98 | 2018 |
Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models JKT Dermawan, M Hitomi, DJ Silver, Q Wu, P Sandlesh, AE Sloan, ... Cancer research 76 (8), 2432-2442, 2016 | 72 | 2016 |
TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ... Elife 7, e30842, 2018 | 42 | 2018 |
TIGIT and PD-1 immune checkpoint pathways are associated with patient outcome and anti-tumor immunity in glioblastoma I Raphael, R Kumar, LH McCarl, K Shoger, L Wang, P Sandlesh, ... Frontiers in immunology 12, 637146, 2021 | 40 | 2021 |
Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene P Sandlesh, T Juang, A Safina, MJ Higgins, KV Gurova PLoS One 13 (6), e0199785, 2018 | 33 | 2018 |
Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles N Ludwig, A Rao, P Sandlesh, SS Yerneni, AD Swain, KM Bullock, ... Neuro-oncology 24 (2), 197-209, 2022 | 25 | 2022 |
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution JR Leistico, P Saini, CR Futtner, M Hejna, Y Omura, PN Soni, P Sandlesh, ... Cell reports 34 (13), 2021 | 13 | 2021 |
Prevention of chromatin destabilization by FACT is crucial for malignant transformation P Sandlesh, A Safina, I Goswami, L Prendergast, S Rosario, EC Gomez, ... Iscience 23 (6), 2020 | 13 | 2020 |
Machine learning identification of immunotherapy targets in low-grade glioma using RNA sequencing expression data P Agarwal, OM Beale, X Zhang, P Sandlesh, E Jaman, N Amankulor World Neurosurgery 163, e349-e362, 2022 | 6 | 2022 |
FACT maintains nucleosomes during transcription and stem cell viability in adult mice I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ... EMBO reports 23 (4), e53684, 2022 | 6 | 2022 |
History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas E Jaman, X Zhang, P Sandlesh, A Habib, J Allen, RG Saraiya, ... Journal of Neuro-Oncology 155, 133-141, 2021 | 4 | 2021 |
In vivo efficacy of decitabine as a natural killer cell–mediated immunotherapy against isocitrate dehydrogenase mutant gliomas X Zhang, WJ Kim, AV Rao, E Jaman, CP Deibert, P Sandlesh, K Krueger, ... Neurosurgical Focus 52 (2), E3, 2022 | 3 | 2022 |
FACT-mediated maintenance of chromatin integrity during transcription is essential for viability of mammalian stem cells I Goswami State University of New York at Buffalo, 2021 | 1 | 2021 |
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis A Rao, X Zhang, A Cillo, JH Sussman, P Sandlesh, AC Tarbay, ... bioRxiv, 2024.04. 09.588752, 2024 | | 2024 |
FACT-mediated maintenance of chromatin integrity during transcription is essential for mammalian stem cell viability I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ... bioRxiv, 2021.06. 21.449309, 2021 | | 2021 |
Understanding the role of histone chaperone FACT in mammalian cells using a conditional FACT knockout mouse model I Goswami, P Sandlesh, A Safina, K Gurova TRANSGENIC RESEARCH 29 (SUPPL 1), 14-14, 2020 | | 2020 |
Induction of nucleosome disassembly with small molecules as a novel anti-cancer approach A Safina, P Sandlesh, J Wang, KV Gurova Cancer Research 80 (16_Supplement), 1747-1747, 2020 | | 2020 |
Conditional knockout of histone chaperone FACT in mice: Consequences for normal tissues MA Ito, P Sandlesh, I Goswami, LA Prendergast, K Gurova Cancer Research 79 (13_Supplement), 5193-5193, 2019 | | 2019 |
Generation of a Conditional Knockout of FACT Subunit SSRP1 Mouse Model to Study the Consequences of FACT Inactivation P Sandlesh State University of New York at Buffalo, 2018 | | 2018 |