| A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target A Debnath, D Parsonage, RM Andrade, C He, ER Cobo, K Hirata, S Chen, ... Nature medicine 18 (6), 956-960, 2012 | 332 | 2012 |
| Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs Z Qian, T Liu, YY Liu, R Briesewitz, AM Barrios, SM Jhiang, D Pei ACS chemical biology 8 (2), 423-431, 2013 | 206 | 2013 |
| Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery Z Qian, JR LaRochelle, B Jiang, W Lian, RL Hard, NG Selner, ... Biochemistry 53 (24), 4034-4046, 2014 | 190 | 2014 |
| Interaction of urea with a hydroxide-bridged dinuclear nickel center: an alternative model for the mechanism of urease AM Barrios, SJ Lippard Journal of the American Chemical Society 122 (38), 9172-9177, 2000 | 179 | 2000 |
| Identification of cystathionine β‐synthase inhibitors using a hydrogen sulfide selective probe MK Thorson, T Majtan, JP Kraus, AM Barrios Angewandte Chemie International Edition 52 (17), 4641-4644, 2013 | 163 | 2013 |
| Gold (I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study D Krishnamurthy, MR Karver, E Fiorillo, V Orru, SM Stanford, N Bottini, ... Journal of medicinal chemistry 51 (15), 4790-4795, 2008 | 146 | 2008 |
| Amide hydrolysis effected by a hydroxo-bridged dinickel (II) complex: Insights into the mechanism of urease AM Barrios, SJ Lippard Journal of the American Chemical Society 121 (50), 11751-11757, 1999 | 123 | 1999 |
| Modeling the diiron centers of non-heme iron enzymes. Preparation of sterically hindered diiron (II) tetracarboxylate complexes and their reactions with dioxygen DD LeCloux, AM Barrios, TJ Mizoguchi, SJ Lippard Journal of the American Chemical Society 120 (35), 9001-9014, 1998 | 103 | 1998 |
| Inhibition of lysosomal cysteine proteases by a series of Au (I) complexes: a detailed mechanistic investigation SS Gunatilleke, AM Barrios Journal of medicinal chemistry 49 (13), 3933-3937, 2006 | 101 | 2006 |
| Decomposition of alkyl-substituted urea molecules at a hydroxide-bridged dinickel center AM Barrios, SJ Lippard Inorganic Chemistry 40 (6), 1250-1255, 2001 | 80 | 2001 |
| Identifying potent, selective protein tyrosine phosphatase inhibitors from a library of Au (I) complexes MR Karver, D Krishnamurthy, RA Kulkarni, N Bottini, AM Barrios Journal of medicinal chemistry 52 (21), 6912-6918, 2009 | 79 | 2009 |
| Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au (I) A Chircorian, AM Barrios Bioorganic & medicinal chemistry letters 14 (20), 5113-5116, 2004 | 76 | 2004 |
| Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells SM Stanford, D Krishnamurthy, MD Falk, R Messina, B Debnath, S Li, ... Journal of medicinal chemistry 54 (6), 1640-1654, 2011 | 67 | 2011 |
| A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases Y He, S Liu, A Menon, S Stanford, E Oppong, AM Gunawan, L Wu, DJ Wu, ... Journal of medicinal chemistry 56 (12), 4990-5008, 2013 | 61 | 2013 |
| Auranofin Is an Apoptosis-Simulating Agent with in Vitro and in Vivo Anti-leishmanial Activity ER Sharlow, S Leimgruber, S Murray, A Lira, RJ Sciotti, M Hickman, ... ACS chemical biology 9 (3), 663-672, 2014 | 58 | 2014 |
| Phthalazine-based dinucleating ligands afford dinuclear centers often encountered in metalloenzyme active sites AM Barrios, SJ Lippard Inorganic Chemistry 40 (5), 1060-1064, 2001 | 56 | 2001 |
| Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine S Mitra, AM Barrios Bioorganic & medicinal chemistry letters 15 (23), 5142-5145, 2005 | 55 | 2005 |
| Diiron complexes of 1, 8-naphthyridine-based dinucleating ligands as models for hemerythrin C He, AM Barrios, D Lee, J Kuzelka, RM Davydov, SJ Lippard Journal of the American Chemical Society 122 (51), 12683-12690, 2000 | 55 | 2000 |
| A luminogenic lanthanide-based probe for the highly selective detection of nanomolar sulfide levels in aqueous samples ML Aulsebrook, S Biswas, FM Leaver, MR Grace, B Graham, AM Barrios, ... Chemical communications 53 (36), 4911-4914, 2017 | 53 | 2017 |
| Inhibition of cathepsin B by Au (I) complexes: a kinetic and computational study SS Gunatilleke, CAF De Oliveira, JA McCammon, AM Barrios JBIC Journal of Biological Inorganic Chemistry 13, 555-561, 2008 | 50 | 2008 |
