Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins. G Levkowitz, LN Klapper, E Tzahar, A Freywald, M Sela, Y Yarden Oncogene 12 (5), 1117-1125, 1996 | 226 | 1996 |
Ephrin stimulation modulates T cell chemotaxis N Sharfe, A Freywald, A Toro, H Dadi, C Roifman European journal of immunology 32 (12), 3745-3755, 2002 | 142 | 2002 |
The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1 A Freywald, N Sharfe, CM Roifman Journal of Biological Chemistry 277 (6), 3823-3828, 2002 | 129 | 2002 |
The EphB6 receptor cooperates with c-Cbl to regulate the behavior of breast cancer cells L Truitt, T Freywald, J DeCoteau, N Sharfe, A Freywald Cancer research 70 (3), 1141-1153, 2010 | 99 | 2010 |
EphA and ephrin-A proteins regulate integrin-mediated T lymphocyte interactions N Sharfe, M Nikolic, L Cimpeon, A Van De Kratts, A Freywald, ... Molecular immunology 45 (5), 1208-1220, 2008 | 95 | 2008 |
The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses A Freywald, N Sharfe, C Rashotte, T Grunberger, CM Roifman Journal of Biological Chemistry 278 (12), 10150-10156, 2003 | 88 | 2003 |
Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells N Sharfe, A Freywald, A Toro, CM Roifman The Journal of Immunology 170 (12), 6024-6032, 2003 | 79 | 2003 |
Dancing with the dead: Eph receptors and their kinase-null partners L Truitt, A Freywald Biochemistry and Cell Biology 89 (2), 115-129, 2011 | 75 | 2011 |
Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK … X Tan, A Xu, T Zhao, Q Zhao, J Zhang, C Fan, Y Deng, A Freywald, ... Scientific reports 8 (1), 3769, 2018 | 67 | 2018 |
EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes A Maddigan, L Truitt, R Arsenault, T Freywald, O Allonby, J Dean, ... The Journal of Immunology 187 (11), 5983-5994, 2011 | 51 | 2011 |
Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF‐κB‐Regulated Anti‐Apoptosis and p53/PCNA‐and ATM/ATR‐Chk1/2‐Controlled DNA‐Damage … T Zhao, X Tang, CS Umeshappa, H Ma, H Gao, Y Deng, A Freywald, ... Journal of cellular biochemistry 117 (9), 2138-2148, 2016 | 49 | 2016 |
EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes A Freywald, N Sharfe, CDE Miller, C Rashotte, CM Roifman The Journal of Immunology 176 (7), 4066-4074, 2006 | 46 | 2006 |
TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis A Xu, L Zhang, J Yuan, F Babikr, A Freywald, R Chibbar, M Moser, ... Cellular & Molecular Immunology 16 (10), 820-832, 2019 | 44 | 2019 |
Protein tyrosine kinases: their roles and their targeting in leukemia K K. Bhanumathy, A Balagopal, FS Vizeacoumar, FJ Vizeacoumar, ... Cancers 13 (2), 184, 2021 | 43 | 2021 |
An integrated computational and experimental study uncovers FUT 9 as a metabolic driver of colorectal cancer N Auslander, CE Cunningham, BM Toosi, EJ McEwen, K Yizhak, ... Molecular Systems Biology 13 (12), 956, 2017 | 43 | 2017 |
Building high-resolution synthetic lethal networks: a ‘Google map’of the cancer cell JM Paul, SD Templeton, A Baharani, A Freywald, FJ Vizeacoumar Trends in molecular medicine 20 (12), 704-715, 2014 | 40 | 2014 |
EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours BM Toosi, A El Zawily, L Truitt, M Shannon, O Allonby, M Babu, ... Oncogene 37 (30), 4073-4093, 2018 | 38 | 2018 |
Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway R Wang, A Xu, X Zhang, J Wu, A Freywald, J Xu, J Xiang Cellular & Molecular Immunology 14 (6), 529-545, 2017 | 38 | 2017 |
A novel T cell-based vaccine capable of stimulating long-term functional CTL memory against B16 melanoma via CD40L signaling Y Xie, L Wang, A Freywald, M Qureshi, Y Chen, J Xiang Cellular & molecular immunology 10 (1), 72-77, 2013 | 38 | 2013 |
CD4+ Th2 cells function alike effector Tr1 and Th1 cells through the deletion of a single cytokine IL-6 and IL-10 gene MA Munegowda, S Xu, A Freywald, J Xiang Molecular Immunology 51 (2), 143-149, 2012 | 35 | 2012 |